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Ch 13.
Computed Tomography 13.1 Explain basic principles 13.2 Explain geometry and historical development 13.3 Understand detectors and detector arrays 13.4 Explain slice thickness, pitch 13.5 Explain tomographic reconstruction process 13.6 Understand digital image display 13.9 Explain artifacts
What to expect?
- CT Techniques - Clinical CT applications: head and neck - CT in Cardiology - Dual Energy CT - CT in Archeology
- CT Techniques - Clinical CT applications: chest and abdomen - Radiation dose - Cone Beam CT - CT in Forensics (CSI-Groningen)
What to expect?
- CT Techniques - Clinical CT applications: head and neck - CT in Cardiology - Dual Energy CT - CT in Archeology
- CT Techniques - Clinical CT applications: chest and abdomen - Radiation dose - Cone Beam CT - CT in Forensics (CSI-Groningen)
Toshiba AquilionONE
Philips
Brilliance iCT
G.E.
CT750 HD
Straton X-ray tube diagram (Sensation 64 and Definition) Cooling rate 5 MHU/min
Double z-Sampling:
CT technique
Configuration detector system Sensation 64 and Definition (A-tube) Thin collimation plates Ceramic scintillationmaterial (solide state detector) Very short after glowing time (gadolinium oxi-sulfide) < 0,00043 sec! Photodiode-array
CT technique
Collimation: principle
eff. slice-thickness
Pitch en Table Feed Table feed: per rotation Pitch: table feed per rotation / total width of collimated beam E.g. table feed 12 mm, collimation 16 x 0.75 > beam pitch 1 E.g. table feed 9.6 mm/rotation, collimation 64 X 0.6 (32 x 0.6=19.2 mm) > pitch 0.5
Effective mAs mA.s produkt remains equal. E.g. Increasing pitch > shorter scantime > more mA. E.g. Decreasing rotationtime > longer total scantime > less mA.
Pitch
Is there any influence of the pitch on the spatial resolution? Effective mAs (radiationdose) stays equal. Bushberg, page 345 - 346
What to expect?
- CT Techniques - Clinical CT applications: head and neck - CT in Cardiology - Dual Energy CT - CT in Archeology
- CT Techniques - Clinical CT applications: chest and abdomen - Radiation dose - Cone Beam CT - CT in Forensics (CSI-Groningen)
CT-scan Brain
Protocol CT-scan Brain Indications Standard Trauma Tumor or abces (MRI preferred) Metastases (MRI preferred) Stereolithography Navigation (stereotaxie)
Guidelines for radiology report Increased brain pressure? Brain shifting? Bleeding? Differences in density? Abnormalities: localisation, size and number? Fractures? Bone destruction?
OM
Z: 5 mm/index 5 mm
Z: 3 mm/index 1.5 mm
Bushberg, page 371 - 372
Most common question: Bleeding or no-bleeding? No-bleeding > start - Anti-thrombolytic drugs - Antiplatelet medicine like Aspirin 3D
Abces
MRI-T1
MRI-FLAIR
MRI-T2
MRI-T1 + gado
MPR
Transversal Coronal
MPR Transversal
MPR Coronal
Bushberg, page 359 - 360
MPR
B-cell lymphoma
Coronal
Radiation-dose 0.3 mSv
Axial
Coronal
Coronal
Coronal
Bushberg, page 359 - 360
Axial (transversal)
Anatomy
Golden standard
Scan in 10 15 sec.
Entrance
Entrance
CTA VRT
CTA MIP
Day 3
Day 30
Perfusion-CT
Traumatology
Traumatology
Trauma capitis
SSD
?
VRT
Bushberg, page 360-362
Traumatology
(same patient)
Take Home Message: always start with looking at source images (first reconstruction)
Bushberg, page 360-362
Traumatology
Traumatology
Traumatology
Movement artefacts
Traumatology
Gunshot
Protocol CT-scan Neck Indications Standard Oncology Trauma CTA (Hernia to MRI)
Radiation-dose 1.1 mSv
Guidelines for radiology report Soft tissue evaluation. Pathology? Nodules, glands? CTA: stenosis? CTA: aneurysm? Fractures? Bone destruction?
Maligne lymfoma with necrotic lymph gland. Future: Iterative reconstruction, less artefacts and lower dose!
MPR 1 mm
MPR 3 mm
MPR 5 mm
MPR coronal direction: 1, 3 - 5 mm slice thickness Partial Volume effect: sharp versus unsharp, noisy versus a better S/N ratio
Bushberg, page 371-372
Traumatology
Wear, (slijtage)
Traumatology
Traumatology
Traumatology
Traumatology
Same patient
Break
What to expect?
- CT Techniques - Clinical CT applications: head and neck - CT in Cardiology - Dual Energy CT - CT in Archeology
- CT Techniques - Clinical CT applications: chest and abdomen - Radiation dose - Cone Beam CT - CT in Forensics (CSI-Groningen)
Cardiology
2002 Sensation-16!
Cardiology
Two possibilities: decrease scantime or the heart rate (> 70 bpm beta-blockers) Faster scanning = higher temporal (time) resolution - Rotationtime of 500, 420, 370 up to 270 ms (limitation by G-forces) - Half-scan reconstruction (180 degrees): 250, 210, 185 up to 135 ms
Cardiology
Cardiology
z - Position
Image data
Reco n
Reco n
Delay
Reco n
Reco n
Half scan segment
Time
Cardiology
Siemens
z - Position
Reco n
Dela y
Half scan segment
Reco n
Time
Very low heartrate or table feed (pitch) to high: gaps!
Reco n
Reco n
Cardiology
Gaps in a 16-slice CT
Cardiology
Cardiology
Single Source CT 180 degrees recon Technical challenge with high heart rates
60 bpm 100 bpm
Cardiology
Comparison between Single Source and Dual Source CT Cardio-imaging: high temporal- and spatial resolution
Cardiology
Dual Source CT: principle Normaly only 1 tube (Source) is used for scanning (A-tube, Single Source)
Cardiology
Cardiology
Cardiology
Cardiology
- Sometimes steps between slices - Higher heartrate: bigger and more steps - Use betablockers to decrease heartrate and steps
Cardiology
- Sometimes steps between slices - Higher heartrate: bigger and more steps - Use betablockers to decrease heartrate and steps
Cardiology
Timing of contrast
Test bolus
Standardised automatic Bolus Tracking - place of ROI: Descending Aorta Threshold 100 HU Advantage: less movement, less artefacts compared to Ascending Aorta, operator independent manual
Cardiology
Contrast: Iomeron 400 Injector: MedRad Stellant, Sensation-16 and Sensation-64 Contrast ml/sec Cardiac spiral and sequential Biphasic Cardiac-bypass Extra series 3 5 4 3 5 Saline (NaCl) ml/sec ml
ml 3 80 20 3 60
ml 3 65 80(30-70%) 3 60
4 4
50 30
4 4
30 30
Cardiology
5% 10 % 15 % 20 % 25 % 30 % 35 % 40 % 45 % Start phase 50 % 55 % 60 % 65 % 70 % Manual or automatic (best phase) 75 % 80 % 85 bpm > 65-70% 85 % 90 % 85 bpm < 30-35% 95 % 100 %
65 %
70 %
75 %
80 %
Cardiology
Case
> 50% stenosis & complete occlusion RCA
Male, 57 y Chest-Pain on ER Dual Source CT > CAG > PTA Retrospective spiral CTA with ECG-Pulsing 30-80% full dose, rest 20% dose Start phase reconstruction 70%
No significant stenosis
Cardiology
Systolic phase
Cardiology
Case
Wall thickness ES Wall thickness ED
Wall thickening
Wall motion
Cardiology
Aorta Valves
Recommanded: - 20 Phase recon, 1 mm, index 1 mm (512 matrix) - Kernel medium/sharp - No ECG-pulsing (3-6 mSv)
What to expect?
- CT Techniques - Clinical CT applications: head and neck - CT in Cardiology - Dual Energy CT - CT in Archeology
- CT Techniques - Clinical CT applications: chest and abdomen - Radiation dose - Cone Beam CT - CT in Forensics (CSI-Groningen)
Dual Energy
Dual Energy CT
Dual Energy is based on the unique energy dependant attenuation profiles of different sorts of tissue like fat, soft tissue, bone and contrast.
Dual Energy
Dual Energy is based on the unique energy dependant attenuation profiles of different sorts of tissue like fat, soft tissue, bone and contrast.
Thomas Flohr, First performance evaluation of a DSCT; Eur Radiology (2006)
Dual Energy
Dual Energy
Dual Energy
Bone Subtraction
Dual Energy
Ischemia
Dual Energy
Dual Energy:
Possible applications - differentiation in composite of kidneystones - simply removing of bony structures and calcification by way of subtraction - virtuel reconstruction of a native series - differentiation between benign and malign nodules, cysts and other abnormalities - differentiation between cartilage, tendons and ligaments (traumatology) - detection of inflammation, e.g. in softplaques
What to expect?
- CT Techniques - Clinical CT applications: head and neck - CT in Cardiology - Dual Energy CT - CT in Archeology
- CT Techniques - Clinical CT applications: chest and abdomen - Radiation dose - Cone Beam CT - CT in Forensics (CSI-Groningen)
Archeology
AZG 1973
Archeology
Archeology
hart
Archeology
Unit of Art in Medicine, Manchester; Facial reconstruction made by Denise Smith and Caroline Wilkinson.
Archeology
Unit of Art in Medicine, Manchester; Facial reconstruction made by Denise Smith and Caroline Wilkinson.
Archeology
1 juni 1999 disclosure of the reconstructed head by the acting representative Egyptian ambassador, mr. Ashraf Elkholy.
Archeology
1 juni 1999 disclosure of the reconstructed head by the acting representative Egyptian ambassador, mr. Ashraf Elkholy.
Archeology
Archeology
But is it reliable?
Tarbot
END
What to expect?
- CT Techniques - Clinical CT applications: head and neck - CT in Cardiology - Dual Energy CT - CT in Archeology
- CT Techniques - Clinical CT applications: chest and abdomen - Radiation dose - Cone Beam CT - CT in Forensics (CSI-Groningen)
Image Reconstruction: Backprojection Each individual projection gives a contribution to the eventual picture advancement (beeldopbouw).
Voxels en pixels. In practise we look more to the pixels then to voxels. Realise that a pixel is always an addition of a volume. In an other way: a pixel is a 2-dimensional display of a 3-dimensionale measurement.
CT Chest
level window
40 400
level window
40 400
level window
40 800
Matrix
CT technique Bushberg, page 356
CT technique
CT technique
Spatial resolution
CT technique
contrast resolution
(chicken)
(chop)
CT technique
spatial resolution
CT technique
CT technique
Spatial resolution smal details - interstitial lungtissue - Inner Ear structures - Temporal Mandibulair Joint
method thin slices higher kV lower radiationdose sharp kernel wide window
method - thicker slices - lower kV - relative higher dose (Alara) - soft kernel - small window
What to expect?
- CT Techniques - Clinical CT applications: head and neck - CT in Cardiology - Dual Energy CT - CT in Archeology
- CT Techniques - Clinical CT applications: chest and abdomen - Radiation dose - Cone Beam CT - CT in Forensics (CSI-Groningen)
CT Chest
Scoutview A.P.
Bushberg, page 330
CT Chest
Ascending Aorta
Descending Aorta
Pleural Effusion
Bushberg, page 358
CT Chest
Window-level: lung-setting
CT Chest
Lung Metastasis
CT Chest
CT Chest
CT Chest
Atherosclerosis
CT Chest
CT Chest
CT Chest
CT Chest
Virtual Scopy
CT Chest
CT Chest
CT Abdomen
Stomach Pancreas
Gallstones
Liver
Kidney
Abdominal anatomy
CT Abdomen
CT Abdomen
CT Abdomen
CT Abdomen
Abnormality?
CT Abdomen
CT Trauma
Polytrauma
CT Trauma
CT Trauma
Ultra-sound of the abdomen - fluid in the chest - fluid around spleen and liver CT or Operation Room? -> CT!
CT Trauma
*) Artificial respirating
CT Trauma
CT Abdomen (arterial phase) - Rupture of the spleen - Active arterial bleeding - Fluid round the organs Operation Room? No!
CT Trauma
Groin; liesstreek
CT trauma
CT Trauma
Collateral damage
- Clavicula #
CT Trauma
# Cervical 2
Collateral damage
Break
What to expect?
- CT Techniques - Clinical CT applications: head and neck - CT in Cardiology - Dual Energy CT - CT in Archeology
- CT Techniques - Clinical CT applications: chest and abdomen - Radiation dose - Cone Beam CT - CT in Forensics (CSI-Groningen)
S/N
165 mAs
165 mAs
20 mAs
CT fysics
20 mAs
110 mAs
CT fysics
Object attenuation
CT fysics
standard scan
with AEC
CT fysics
Care Dose 4D
Sensation 64, Dual Source Real-time tube current adaption: up to 66 % dose reduction compared to fixed mA!
CT fysics
140mAs 55mAs
110mAs
CT fysics
Equivalent dose: biological effects in relation to the sort of ionising radiation (mSv) X-rays = factor 1 (protons = 5, neutrons = 5-20, = 20)
Effects: stochastic > no borderline, proportional to dose > tumorinduction and genetic damage
CT fysics
Step one: calculating absorbed dose in mGray CTDI = Computer Tomography Dose Index
CT fysics
A measurement for radiation absorption is CTDIw (mGray). CTDIweighted = 1/3 x CTDIcenter + 2/3 CTDIskin.
D.L.P.
The Dose Length Product says more about the total amount of absorbed dose. DLP = CTDIw x st x n (multiply) st = slicethickness, beamwidth in Z-axis n = number of adjusted slices or rotations
CT fysics
CT fysics
Definition organdose: average absorbed energy per organ (mGray). E = total organdose (mSievert)
E = WT x HT
WT = Organ weighted factor (ICRP 60*) HT = Absorbed organdose x quality factor (1)
CT fysics
Japan: Hiroshima
Total number of Deaths Immediately: 78.000 End 1945: 140.000 2004: 237.062
CT fysics
Organ sensitivity after the A-bom radiation, Hiroshima (RERF, Radiation Effects Research Foundation)
Table. Numbers of cancer deaths by cancer type and strength of evidence for a radiation effect.
____________________________________________________________________ Total Estimated Evidence for Site Total Estimated Evidence for Deaths Excess Effect Deaths Excess Effect ____________________________________________________________________ Stomach Lung Liver Uterus Colon Rectum Pancreas Esophagus 2529 939 753 476 347 298 297 234 65 67 30 9 23 7 3 14 12 strong strong strong moderate strong weak weak strong moderate F. Breast Ovary Bladder Prostate Bone 211 120 118 80 32 37 10 10 2 3 47 1 6 strong strong strong weak moderate strong weak strong Site
Gallbladder 228
CT fysics
Absorbed dose (mGy) > organdose (mSv) Weight factors: ICRP-norm Weightfactors for calculation of the effective (organ) dose.
(ICRP #26, 1977) (ICRP #60, 1990) Gonads Bone Marrow Colon Lung Stomach Bladder Breast Liver Oesophagus Thyroid Skin Skeleton Remainder Sum 0,25 0,12 0,12 0,15 0,03 0,03 0,30 1,00 0,20 0,12 0,12 0,12 0,12 0,05 0,05 0,05 0,05 0,05 0,01 0,01 0,05 1,00
What to expect?
- CT Techniques - Clinical CT applications: head and neck - CT in Cardiology - Dual Energy CT - CT in Archeology
- CT Techniques - Clinical CT applications: chest and abdomen - Radiation dose - Cone Beam CT - CT in Forensics (CSI-Groningen)
Cone Beam CT
Disadvantages 3D to 2D
2006
NewTom 3G DVT
Cone Beam CT
Cone Beam CT
Cone Beam CT
LA Feldkamp, LC Davis, JW Kress: Practical cone-beam algorithm J. Opt. Soc. Am. (1984), 612-619
Cone Beam CT
Cone Beam CT
Panoramic Images
Cone Beam CT
Made by a Cone-Beam CT
Cone Beam CT
Effective dose
Illuma 137 S
NewTomVG 75 S
Ewoo 70 S
Kavo/Icat 68 S
NewTom 36 S
Galileos 29 S
Cone Beam CT
Planmeca ProMax 3D
2010
What to expect?
- CT Techniques - Clinical CT applications: head and neck - CT in Cardiology - Dual Energy CT - CT in Archeology
- CT Techniques - Clinical CT applications: chest and abdomen - Radiation dose - Cone Beam CT - CT in Forensics (CSI-Groningen)
Forensic Radiology
Forensic Radiology
Forensic Radiology
Forensic Radiology
Dental identification
UMCG
Forensic Radiology
Dental identification
We had a match!
UMCG
Forensic Radiology
http://www.fbi.gov
Forensic Radiology
www.fbi.gov
www.marylandmissing.com
www.missingpersons.org
Forensic Radiology
Forensic Radiology
Forensic Radiology
Forensic Radiology
Rochelle
Rowena
Forensic Radiology
Forensic Radiology
Mouse !!!