This audio program presents diagnostic and treatment aspects of disruptive mood dysregulation disorder, predictors of long-term outcome in youths with bipolar disorder, reading ability and elements of impulsivity related to aggression in schizophrenia, a global health review of a woman in Uganda with HIV and major depression, and the connection between schizophrenia and maternal levels of C-reactive protein. Articles can be viewed online at www.ajp.psychiatryonline.org.