This podcast was made in conjunction with PedsCases and the Canadian Paediatrics Society (CPS) to summarize the recently published 2017 CPS Practice Point: Management of Infants born to Mothers who have used Opioids during pregnancy.  In this episode, listeners will learn about the presentation of Neonatal Abstinence Syndrome (NAS) and its differential, the assessment of an infant with NAS, and the treatment and discharge planning of an infant and their family. The podcast was developed by Dr. Maya Dhahan, a second-year Paediatrics Resident, in collaboration with Dr. Thierry Lacaze, staff Neonatologist and Section Chief for the Department of Neonatology at the University of Calgary, and the lead author of the CPS statement.