Madness has always intrigued artists, and medieval paintings sometimes presented this malady's treatment via the surgical removal of cranial stone. What was the stone of madness? Was it mere fantasy, metaphor or an actual medical condition? In this classic episode of Stuff to Blow Your Mind, Robert and Joe collect their trepanation tools and investigate. (Originally published Jan 7, 2016) Learn more about your ad-choices at https://news.iheart.com/podcast-advertisers