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Midterm Exam 1
Date: Monday April 30 Time: 5:00-6:50 PM Topics: Molecular Structure: Introduction and Review Carbohydrates Location: last name A-H in Franz 1178 last name I-Sh in Haines 39 last name Si-Z in PAB 1425 Question and Answer Session Lecture time, Monday April 30 Submit questions to harding@chem.ucla.edu Label as Question for Q&A Deadline for possible inclusion: noon Sunday April 29 Extra Office Hours (Steve J): Sunday 2-4 PM, Young Hall 3077F
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Bending (H-O-H) Motion not along bond axis Less important than stretching
Molecular Vibrations
Vibration energy vibration energy average bond length
add energy
Molecular Vibrations
Vibration energy Vibrational energy is quantized (only certain energy values are possible) Vibrational state energy
For bond vibrations: DE = dependent on bond = ~5 kcal mol-1 = lower energy than red light photons = infrared photons
Y d-
Bond dipole ~ (magnitude of electronegativity difference) x (bond length) DEN dipole bond length dipole bond dipole absorption In practical terms: Highly polar bond strong peak Symmetrical (nonpolar) or nearly symmetrical bond peak weak or absent
Examples:
H3C CH3
H3C
CH3
CH3
H
Caution! Weak peaks not always discernable Be careful when excluding symmetrical functional groups base on absence of peak
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Stretching frequency =
1 2c
Fingerprint region
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Aryl* or vinyl** sp2 C-H Alkyl sp3 C-H Aldehyde C-H Carboxylic acid O-H
2260-2000 cm-1
2260-2220 cm-1 Zone 4: 1850-1650 cm-1
1725-1700 cm-1
1690-1650 cm-1
strong
strong
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Complete table: Thinkbook, inside front cover What do I have to know? Functional groups in each zone Learn by working lots of problems Do not memorize stretching frequencies; table given on exam
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C-C
CH2CH2CH2CH3
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H H C H C CH2CH2CH2CH3
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broad
C-O
CH2CH2CH2CH2CH2CH3
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very strong
1718 cm-1
O C H3C CH2CH3
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20
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very strong
1718 cm-1
O C H3C CH2CH3
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very strong
1718 cm-1
O C H CH2CH2CH2CH2CH3
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1720 cm-1
O C H3C C H H C H
1743 cm-1
O C CH3O CH2CH2CH2CH2CH3
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1711 cm-1
O H O C CH2CH2CH2CH2CH3
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H3C
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1700 cm-1
Step 1: Calculate DBE DBE = C - (H/2) + (N/2) + 1 = 6 - (12/2) + (0/2) +1 =1 One ring or one pi bond
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1700 cm-1
Step 2: Analyze IR Spectrum Zone 1 (3700-3200 cm-1) Alcohol O-H: Present N-H: Absent - no N in formula C-H: Absent - not enough DBE
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1700 cm-1
Zone 2 (3200-2700 cm-1) Aryl/vinyl sp2 C-H: Alkyl sp3 C-H: Aldehyde C-H: Carboxylic acid O-H:
Probably not (not enough DBE) Present Absent - no 2700 cm-1 Absent - not broad enough
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1700 cm-1
Zone 3 (2300-2000 cm-1) Alkyne CC: Absent - no peaks; not enough DBE Nitrile CN: Absent - no peaks; not enough DBE
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1700 cm-1
Zone 4 (1850-1650 cm-1) C=O: Present @ 1700 cm-1 Possibilities: ketone ester - not enough oxygens aldehyde - no 2700 cm-1 peak carboxylic acid - zone 2 not broad amide - no nitrogen
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1700 cm-1
Zone 5 (1680-1450 cm-1) Benzene ring: Absent - no peak ~1600 cm-1; not enough DBE Alkene C=C: Absent - no peak ~1600 cm-1; not enough DBE
O OH
Actual structure:
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Step 1: Calculate DBE DBE = C - (H/2) + (N/2) + 1 = 8 - (7/2) + (1/2) +1 =6 Six rings and/or pi bonds Possible benzene ring
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Step 2: Analyze IR Spectrum Zone 1 (3700-3200 cm-1) Alcohol O-H: Absent - no oxygen in formula N-H: Absent - peaks too small C-H: Absent - peaks too small
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Zone 2 (3200-2700 cm-1) Aryl/vinyl sp2 C-H: Alkyl sp3 C-H: Aldehyde C-H: Carboxylic acid O-H:
Present - peaks > 3000 cm-1 Present - peaks < 3000 cm-1 Absent - no 2700 cm-1; no C=O in zone 4 Absent - not broad enough; C=O in zone 4
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Zone 5 (1680-1450 cm-1) Benzene ring: Present - peaks ~1600 cm-1 and ~1500 cm-1 Alkene C=C: Absent - not enough DBE for alkene plus benzene plus triple bond Actual structure:
CH2C N
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