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LYMPH NODE
Berkaitan dengan:
Formation of lymph
Fluid leaves capillaries by diffusion and filtration Escaped proteins If lymph flow blocked = tissue swelling or edema Specialized lymphatic capillaries in vili of small intestine transport lipids - they are called lacteals, and the fluid is called chyle.
Lymphatic Vessels
Begin as closed ended lymph capillaries in tissue
spaces between cells NOT A CIRCULATING FLUID Interstitial fluid drains into lymphatic capillaries, forming lymph. Lymph capillaries merge to form lymphatic vessels Lymphatic vessels carry lymph into and out of lymph nodes and finally back to the vascular system.
Lymphatic vessels
Resemble veins (same 3 layers) Found throughout body except:
Avascular tissues Central nervous system Splenic pulp Bone marrow
COMPOSITION
LYMPHATIC CAPILLARIES
ICF
ICF
ECF
ICF
ECF
ICF
ECF
ICF
ECF
Ingestion of 1L of water
Dehydration
Thirst
Liver
Angiotensin II
Blood vessels
Adrenal cortex
Brain
Vasoconstrictor
Aldosteron secre.
ADH secretion
Thirst
Sodium reabs.
H2O reabsorption
Water intake
Direct effect on adrenal cortex Increased aldosterone secretion Increased plasma aldosterone
Increase luminal membrane permiablility to Na+ and K+ & Increase basolateral membrane Na+/K+-ATPase activity in collecting duct principal cells.
Starling Hypothesis
The balance of hydrostatic and oncotic pressures across the capillary endothelium
Mean capillary hydrostatic pressure (Pc): 25 mmHg (40 10) Interstitial fluid hydrostatic pressure (PIF): 0 mmHg Capillary oncotic pressure (c): 28 mmHg
Definition of Edema:
An increase in the interstitial compartement of extracellular fluid volume (Harrisons).