KRITIS STROKE Nurpudji A Taslim Nutrition Department School of Medicine Hasanuddin University @2008 STROKE KEMAMPUAN MAKAN + MASALAH : - PENDERITA - KELUARGA ? N U T R I S I F I S I O T E R A P I M E D I K A A M E N T O S A T I N D A K A N PENDAHULUAN TUJUAN PENGELOLAAN NUTRISI
Mempertahankan fungsi neurologi Fasilitasi pengembalian fungsi-fungsi tubuh secara optimal
ADA 3 HAL PENTING PADA KASUS CRITICAL ILL Hipermetabolisme Hiperkatabolisme Immunosupressan KAPAN NUTRISI ENTERAL DIBERIKAN Pemberian nutrisi enteral direkomendasikan setelah kondisi hemodinamik stabil Memasuki fase flow PEMBERIAN KALORI BERDASARKAN Antropometri Timbang berat badan (BB) Kasus BB normal dan cenderung malnutrisi BB actual ( Brocca) Orang dewasa dengan obesitas menggunakan perhitungan BB Ideal (BBI)
PENILAIAN STATUS NUTRISI Penilaian perubahan body composition akibat berkurangnya pergerakan badan Pemeriksaan biokimia laboratorium Pasca perawatan malnutrisi dukungan nutrisi yang adekuat PENGELOLAAN NUTRISI Stroke akut hipermetabolik Pasca stroke Penilaian status nutrisi Pemeriksaan dan penghitungan kebutuhan nutrien Penentuan jenis, bentuk, cara dan jalur pemberian nutrien Pemantauan dan evaluasi penyesuaian EBB PHASE RESPONSE FLOW PHASE Acute response Adaptive response Hypovolemic Shock +Tissue perfussion + metabolic rate +Oxygen Consump. +Blood pressure +Body temperature Catabolism predominates Glucocorticoid Glucagon Cathecolamine, Release of cytokines, lipid mediators, Production of acute phase protein Excretion of nitrogen Metabolic rate Oxygen consumption Impaired utilization of fuel
Anabolism predominates
Hormone response gradually diminish +Hypermetabolic rate Associated with recovery Potential for restoration of body protein Wound healing depends in part on nutrient intake CHARACTERISTIC OF METABOLIC PHASE OCCURRING AFTER SEVERE INJURY Source: Krauses FOOD,NUTRITION & DIET THERAPY, 2004 Changes in metabolic rate with various type of physiiologic stress. Normal ranges are indicaed by shaded areas. 0 30 60 90 120 150 180 0 10 20 30 40 50 60 70 Days R e s t i n g
M e t a b o l i s m
( %
n o r m a l ) Major burn Peritonitis Fracture Partial Starvation Total Starvation SOURCE:HANDBOOK OF CLINICAL NUTRITION, 1997 NORMAL RANGE Changes in nitrogen excretion with various types of physiologic stress 0 4 8 12 16 20 24 28 0 10 20 30 40 Days N i t r o g e n
e x c r e t i o n
( g / d a y ) Major burn Skeletal trauma Severe sepsis Infection Elective op Partial Starvation Total Starvation SOURCE:HANDBOOK OF CLINICAL NUTRITION, 1997 NORMAL RANGE Hipoksia, Inflamasi, Nekrosis, Trauma Infeksi Respons: Lokal Sistemik PENILAIAN KEBUTUHAN KALORI Sangat sulit Basal Expenditure Energy (BEE) bisa meningkat Estimasi BEE: A. Indirect Calorimetri B. Harris Benedict Equation C. Resting Expenditure Energy (REE)
HARRIS BENEDICT EQUATION LAKI-LAKI
BEE = 66 + 13,7 W + 5 H 6.8 A
PEREMPUAN
BEE = 655 + 9.6 W + 1.7 H 4.7 A
ACTIVITY FACTORS 1,2 for pt confined in bed 1,3 for ambulatory pt 1.2 1,75 most normally active person 2,0 extremely active person
INJURY FACTORS 1,2 minor surgery 1,35 skeletal trauma 1,44 elective surgery 1,6 1,9 mayor sepsis 1,88 trauma plus steroid 2,1 2,5 severe thermal burn
PENILAIAN KEBUTUHAN LEMAK Menurunkan lemak total Menurunkan lemak jenuh dan kolesterol Menurunkan kalori apabila penderita overweight /obese MODEL DIET Diet langkah I Total lemak s 30% Lemak jenuh < 10% PUFA : sampai 10% MUFA : sampai 15% KH : > 55% Protein : 15% Kolesterol : < 300 mg/hari
Diet langkah II Total lemak s 30% Lemak jenuh < 7% PUFA : sampai 10% MUFA : sampai 15% KH : > 55% Protein : 15% Kolesterol : < 200 mg/hari
PENILAIAN KEBUTUHAN PROTEIN Ekskresi nitrogen Anjuran : 1.5 2.2 g/kgBB/hari secara bertahap Pemantauan : UUN dan kreatinin urin Monitor : fungsi ginjal (ureum & kreatinin) dan fungsi hepar Brain Chaned Amino Acid (BCAA) dapat dipertimbangan (pada pasien dengan hepatic encephalophaty) Serum albumin dipertahankan diatas 2.2 g/dL. CARA MENGHITUNG KEBUTUHAN NITROGEN 1. Berdasarkan sekresi urea pada urine [urinary urea nitrogen = UUN]. Untuk ini dibutuhkan urine tampung 24 jam. Langkah- langkah yang harus dilakukan: Ukur UUN 24 jam Hitung total UUN dengan menggunakan rumus:
Hitung asupan protein penderita/hari Hitung nitrogen balans dengan menggunakan rumus:
Keterangan : asupan protein yang dikonversi ke nitrogen = 6.25 UUN = 4 gr [rata-rata nitrogen yang dikeluarkan melalui urine]
100 ] . ][ [ Urine Vol UUN totalUUN = ] 4 [ 25 . 6 Pr sup ] / [ + = A UUN otein an A hari g N Contoh: Seorang penderita yang mempunyai asupan protein 62.5 g/hari sekresi urin 500 mg/dl UUN dalam 2000 ml urine
Maka: UUN = 500 x 2000/100 = 10.000 mg atau 10 gr
N [g/hari] = [62.5/6.25] [10 + 4] = 10 14 = - 4 (negatif nitrogen balance) 2. Berdasarkan kebutuhan energi penderita: tentukan kebutuhan energi penderita dalam sehari Perkirakan ratio energi dan nitrogen, hal ini bervariasi tergantung kondisi penderita. Dapat digunakan 1:150 untuk proses anabolisme dan atau 1:200 untuk maintenance Hitung kebutuhan nitrogen dengan menggunakan rumus:
Contoh: Diasumsikan kebutuhan energi penderita sehari=2250 kcal, dan ratio kcal nitrogen 1:150, maka kebutuhan nitrogen penderita tersebut adalah:
Dengan menggunakan hasil tersebut di atas dapat ditentukan kebutuhan protein: Pro[g] = Nitrogen [g] x 6.25 = 15 x 6.25 = 95.75 protein Nratio Kcal Kcal g KebutuhanN : ] [ = gNitrogen g N 15 150 2250 ] [ = = PENILAIAN KEBUTUHAN ELEKTROLIT
Monitor kadar elektrolit dalam darah : Na, K, Cl , HCO3, Ca Monitor Blood Gas
JALUR PEMBERIAN NUTRISI Nutrisi enteral Nutrisi parenteral (perifer atau sentral) Kombinasi enteral + parenteral Penilaian Nutrisi
Fungsi Saluran Pencernaan Ya Tidak Nutrisi Enteral Nutrisi Parenteral Fungsi Sal Cerna Jangka pendek Jangka panjang atau Pembatasan cairan
Fungsi saluran cerna membaik Jangka panjang Gastrostomi Jejunostomi Jangka pendek Nasogastrik Nasoduodenall Nasojejunal
Nutrisi Parenteral Perifer
Nutrisi Parenteral Total
INDIKASI NUTRISI ENTERAL DAN PARENTERAL Keputusan untuk memulai Dukungan Nutrisi Khusus Normal
Nutrisi Lengkap
Compromised
Formula Khusus
Mencukupi Berlanjut ke Makanan Oral Tidak mencukupi Nutrisi parenteral Sebagai suplemen Mencukupi Diet yg lebih Kompleks dan Makanan oral Sesuai dengan penerimaan Dilanjutkan ke nutrisi Enteral total Ya Tidak Nutrients Tolerance
Sumber: ASPEN Board of Directors Guidelines for the use of Parenteral and Enteral Nutrition in adult and pediatric Patients. JPEN 1993: 17.
KEUNTUNGAN NUTRISI ENTERAL Ekonomis Memacu sekresi hormon pencernaan Mencegah atrofi villi Menghambat pertumbuhan bakteri dan translokasi bakteri Tanpa resiko sepsis kateter dan flebitis. Heimburger, Douglas C. Handbook of Clinical Nutrition. Mosby, 1997. P 209 211. INDIKASI NUTRISI ENTERAL Diberikan secara oral perhatikan cita rasa
Bisa juga menggunakan cara : Nasogastric feeding Gastro tube feeding Jejunos INDIKASI NUTRISI PARENTERAL 1. post op 3-4 hari 2. peradangan usus 3. fistula enterokutaneus 4. short bowel sindrom 5. pankreatitis akuta, tambahan oral kebutuhan meningkat 6. hiperkatabolik akut renal failure 7. terapi tambahan kanker 8. luka bakar hebat, malformasi traktus gastrointestinal (TGI) pada neonatus 9. koma hepatik
PENGELOLAAN NUTRISI PADA PASCA STROKE Pantau sesering mungkin Modifikasi diet Modifikasi diet bila ada kesulitan mineral
KEBUTUHAN KALORI PASCA STROKE 23 28 kcal/kgBB/hari (parese) Pantau BB : hindari BB yang berlebihan Dekubitus tingkatkan kebutuhan protein EATING DISORDER Anorexia Nervosa Bulimia Nervosa Other Conditions CHAPTER OBJECTIVES 1. Contrast healthy attitudes toward uses of food with behavior pattern that could lead to unhealthy uses of food 2. Outline the causes of, effects of, typical persons affected by and treatment for anorexia nervosa. 3. Outline the causes of, effects of, typical persons affected by and treatment for anorexia bulimia 4. Describe still other forms of eating disorder; binge- eating disorder, night eating syndrome and the athlete triad 5. Relate the presence of eating disorders to current social trends 6. Describe methods to reduce the development of eating disorders, including the use of warning signs to identify early cases To understand the differences between various eating disorders e.g. anorexia and bulimia nervosa To consider causative factor presenting features, at risk groups, medical complications, prevention and treatment 1. Refresh your memory 2. From ordered to disordered eating habits 3. Anorexia Nervosa 4. Anorexia Bulimia 5. Prevention of eating disorders REFRESH YOUR MIND
YOU MAY REVIEW:
The effects of neurotransmitters on food intake The role of genetic risk in disease susceptibility Calculation of BMI The effects and treatment of osteoporosis The effects and treatment of iron deficiency anemia EATING BEHAVIORS
Why do we eat? Internal hunger Energy external pleasure, social, personality, environment What is abnormal eating behavior? Abnormal eating behavior = eating disorder? EATING BEHAVIORS Why do we stop eating ? We stop eating when we are satisfied?
Eating is a behavior, not necessarily related to hunger or fullness
MANY OF US, OCCASIONALLY EAT UNTIL WERE STUFFED AND UNCOMFORTABLE Problems controlling our food intake and body weight Progressive weight gain lead to medical problems Associated with simple overeating and too little physical activity Obesity chronic diseases most common eating disorder in our society Some people are more susceptible to these eating disorders than other people are for genetic, physiological and physical reasons Successful treatment must go beyond nutritional therapy Eating disorders any age in both female and male, not restricted to any socio-economic class or ethnicity
FROM ORDERED TO DISORDERED EATING HABITS Eating : completely instinctive behavior for animal extra ordinary number of physiological, social and culture purposes for humans Take a religion meanings Signify bonds within family and ethnic groups Provide a means to express hostility, affection, prestige or class values Within the family, supplying, preparing and distributing food may be a means of expressing love, hatred or even power IN FACT MEDIA, AUDIOVISUAL INFLUENCES Ultraslim body will bring : happiness Love ultimately success
Contradictory Much society becoming fatter/obese FOOD : MORE THAN JUST A SOURCE OF NUTRIENTS From birth adult; food link with personal and emotional experiences Food can be symbol of comfort Eating stimulate neurotransmitter (serotonin) and natural opiods (endorphins)---produce a sense of calm and euphoria in the human body Stress some people turn to food for a drug like, calming effect USING FOOD AS A BARGAINING Contributing to abnormal eating behavior Extreme lead to disordered eating Mild or short term change effect of stressful or illness or desire to modify the diet for variety of health and personal appearance reason Problems bad habit, a style eating adapted from friends or family members or an aspect of preparing for athlete competition Disordered eating: lead to weight loss or weight gain certain nutritional problems requires in depth professional attention. sustained, distressing professional intervention
ANOREXIA NERVOSA An eating disorder involving a physiological loss or denial of appetite Followed by self starvation Related in part to distorted body image and to various social pressure commonly associated with puberty BULIMIA NERVOSA An eating disorder in which large quantities of food are eaten at one time (binge eating) and then purged from the body by vomiting or misuse of laxative, diuretics or enemas
Alternate means to counteract the binge behavior are fasting and excessive exercise BINGE EATING DISORDER An eating disorder characterized by recurrent binge eating and feelings of loss of control over eating that have at least 6 months
Can be triggered by frustation, anger, depression, anxiety, permission to eat forbidden food and excessive hunger PROGRESSION FROM ORDERED TO DISORDERED EATING Anxiety to hunger and satiety signal; limitations of calorie intake to restore weight to healthful level
Some disordered eating habits begins as weight loss is attempted very restricted eating
Clinically evident eating disorder recognized MEDICAL COMPLICATIONS OF ANOREXIA NERVOSA AND BULIMIA NERVOSA Cardiovascular : arrhythmia, bradycardia, oedema cardiomyopathy, hypotension, peripheral cyanosis Dermatologic : callus formation on hands, carotene pigmentation, dry skin/nails, lanugo hair, thinning scalp hair, irritation at corners of mouth Endocrine : amenorrhoea, decreased triiodothyronine and thyroxine levels, increased cortisol and growth hormone levels Gastrointestinal : bloating, early satiety, constipation, dental caries, diarrhoea, oesophageal rupture Hematologic : mild anaemia, low white blood cell count Metabolic : hypokalemia, hyponatremia, hypokalemia Musculoskeletal : delayed bone maturation, reduced stature, osteoporosis, seizures TYPICAL CHARACTERISTIC OF ANOREXIA NERVOSA Loss weight >85% : BMI <17,5 False body perception Ritual involving food Maintain of rigid control in lifestyle Felling of panic after small weight gain Felling of purity, power and superiority Preoccupation of food Helplessness in the presence of food Lack of menstrual periods for at least 3 months Possible presence of bingeing and purging practices
TYPICAL CHARACTERISTICS OF BULIMIA NERVOSA Secretive binge eating (not in front of others) Eating when depressed or under stress Bingeing on a large of food followed by fasting, laxative or diuretic abuse, itself induce vomiting or excessive exercise Fluctuating weight Shame, embarrassment, deceit and depression, low self esteem and guilt Loss of control, fear of not being able to stop eating Perfectionism ; people pleaser Erosion of teeth, swollen glands Purchase of syrup of ipecac to induces vomiting PHYSICAL EFFECTS OF ANOREXIA NERVOSA Lower body temp Slowed metabolic rate from decreased synthesis of thyroid gland Decreased heart rate Iron deficiency anemia Rough, dry, scaly, and cold skin Low WBC Abnormal feeling of fullness or bloating Loss of hair Appearance of lanugo Constipation Low blood potassiumheart rhythm disturbancedeath Loss of menstrual periods Loss of teethacid erosion Muscle tears and stress fractures in athlete--- decreased bone and muscle mass
TREATMENT OF ANOREXIA NERVOSA Nutrition therapy Gain the persons cooperation and trust Gain weight 2-3 pounds/weeks Monitoring blood levels of mineral (K, PO4, Mg) Maintain adequate food intake Psychological and related therapy Emotional problems Use cognitive behavior therapy Family therapy Food is a drug of choice for anorexic patient
HEALTH PROBLEMS STEMMING FROM BULIMIA NERVOSA Demineralization of teeth as an impact of the acid in vomit Blood potassium drops significantly Salivary gland swollen Stomach ulcer and bleeding Constipation Ipecac syrup induced vomitingis toxic to the heart, liver and kidneys TREATMENT OF BULIMIA NERVOSA Decreased the amount of food consumed in binge session Psychotherapy improved self acceptance less concern about body weight Cognitive behavior Pharmacological therapy may be beneficial in conjunction with other therapy Nutrition counseling Correcting misconceptions about food Re-establishing regular eating habits