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Hematopoiesis: overview
Medullary
Origin of blood cells and sequential sites of normal blood production within the bone marrow
Extramedullary
About three months of life, see platelets About five months of life, see leukocytes
Storage Pools
Granulocytes and platelets also exist in two pools
Circulating Marginal
Osteoblasts
Responsible for the formation, calcification and maintenance of the bone structure Large irregularly shaped cells in the bone marrow that may be confused with plasmacytes or malignant cells
Osteoclasts
Responsible for absorption of bone Assist in degradation of bone Giant multinucleated, irregularly shaped phagocytic cells in the bone marrow that may be confused with megakaryocytes
Osteoblast
Osteoclast
References
Harmening, D. M. (2009). Clinical Hematology and Fundamentals of hemostasis (5th ed.). Philadelphia, PA: F.A. Davis Company. McKenzie, S. B. (2010). Clinical Laboratory Hematology (2nd ed.). Upper Saddle River, NJ: Pearson Education, Inc..