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Water is used extensively for making the dialysate of dialysis fluid it is mixed with of special electrolytes.
The quality of water used is therefore critical to the preparation of a dialysis fluid that is free of contamination which have harmful effects on the health of the Haemodialysis patients.
INTRODUCTION
Water has the unique property of being an excellent solvent, high heat capacity and surface tension and hence it is very susceptible to be contaminated to the point where it becomes a health hazard.
The contaminants which may be present in water includes suspended solids, dissolved organics and inorganics, heavy metals & trace minerals and micro organisms.
1. Suspended Solids
Sand Silica
2. Dissolved Inorganics
Calcium Sodium Magnesium Nitrates Sulphates
3. Dissolved Organics
Chloramines Pesticides
5. Micro organisms
Bacteria Pyrogen Algae
6. Endotoxin
Aluminium
Dialysis encelopathy Bone diseases Microcytic anaemia
Calcium / Magnesium
Hypercalcaemia / Hypermagnesaemia Nausea Vomiting Muscle weakness
Chloramine
Haemolyisis Anaemia
Fluoride
Osteomalacia Osteoporosis
Sodium
Hypertension Pulmonary oedema Tachycardia Vomiting Headache
Zinc
Anaemia Nausea Vomiting
pH
Heparin inactivation Itchiness Nausea Vomiting
Microbial
Pyrexial reaction
Sulphate
Nausea Vomiting Metabolic acidosis
To prevent damage to the hydraulic parts in the machine To facilitate production of dialysate of correct electrolyte content To prevent long term side effects of untreated water
ACCEPATABLE WATER
Calcium & Magnesium should be < 0.5 ppm Free from chlorine Free from ions Bacteria count < 200 cfu / ml (AAMI std) Endotoxin level < 2 EU / ml (AAMI std) Meets AAMI standards
*cfu = colony forming unit * AAMI = Association of the Advancement of Medical Instrumentations
Deionizer
Replace all cations & anions with hydrogen & hydroxide ions which in turn, combine to form water molecules. There is the separate column type or the mixed resin column type commonly used in home hemodialysis.
Utilises semipermeable membrane & high pressure to separate water from the contaminants present in the adequately treated water. The RO actively repels ions & organic contaminants while allowing pure water to pass through the microporous membrane surfaces.
Diagram
55% Rejected Water HD Station
45%
Ultraviolet
Guard Filter
Carbon Filter
Water Softener
Sediment Filter
Daily recording of the various parameters as required by the manufacturer which includes:
-
Pump pressures Temperature Conductivity Flow rates Some others as per log sheet
Regular sampling 6 monthly of: - raw water - pre-treated water - treated water
Regular preventive maintenance which include cleaning of membrane and changing filters
Replace membranes when output is below 60% of original output or when TDS is too high.