5.5 Regulacin.

The immune-adrenal axis

5.6 Fisiologa del sistema. Renina angiotensina

Angiotensin II (half-life, 1 min).

Renina 10 to 20 min

Angiotensin II influences sodium homeostasis

changes renal blood flow maintain a constant glomerular filtration rate.

changing the filtration fraction of sodium . release aldosterone.

5.7 Glucocorticoides.

5.7.1 Accin.
METABOLISM

1. the blood glucose :

-antagonizing the secretion and actions of insulin.

-gluconeogenesis. 2. Protein: -mainly catabolic

METABOLISM

3. Liver:

-stimulate the synthesis of certain enzymes

4. regulate fatty acid mobilization by enhancing the activation of cellular lipase

Leukocytosis.
depletion of circulating eosinophils.

inhibit the production and action of the mediators of inflammation:lymphokines and prostaglandins.
inhibit the production and action of interferon by T lymphocytes and the production of IL-1 and IL-6 by macrophages

inhibit the production of T cell growth factor (IL-2) by T lymphocytes. Reverse macrophage activation and antagonize the action of migration-inhibiting factor (MIF). Reduce prostaglandin and leukotriene production by inhibiting the activity of phospholipase A2.

inhibit the production and inflammatory effects of bradykinin, platelet-activating factor, and serotonin

Josef Straka (1864-1946)

5.8 Mineralcorticoides.

5.8.1 Efectos en epitelio

5.8.2 Efectos sobre clulas no epiteliales

1. They do not modify sodium-potassium homeostasis. 2. Aldosterone modifies the expression of several collagen genes and/or genes controlling tissue growth factors. 3. Some effects on nonepithelial cells may be via nongenomic mechanisms. 4. Some of these tissuesthe myocardium and vasculaturemay also produce aldosterone, although this theory is controversial.

5.9 Andrgenos.

Baja intensidad dbil de la cortisolemia.

> 60% PAM de la cortisolemia tanto mayor cuanto mayor es la intensidad del trabajo. Mayor de la cortisolemia cuanto mas depleccionado est el glucgeno.

Lesin con dolor agudo de la cortisolemia.

de la cortisolemia tanto en ejercicios estticos como dinmicos.

6. PANCREAS ENDOCRINO

6.1 Anabolismo y catabolismo de la glucosa.

6.2 Insulina.
6.2.1 Sntesis. Molcula Insulina.

LANGERHANS, Paul (1847-1888)

6.2.2 Secrecin.

6.2.2 Secrecin.

6.3 Glucagn.
6.3.1 Sntesis. Molcula Glucagn

6.4 Acciones Insulina y Glucagn.

Ejercicio a 30 Insulina.

Ejercicio nmero de receptores y la sensibilidad a la insulina.

http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=end ocrin -