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3. The Effects of Microcirculatory
Ischemic Hypoxia
1) Compensation :
Precapillary arteriole
sphincter
postarteriole
后微动脉
③ heart function ↑.
noradrenaline and
adrenaline ↑
Vasoconstriction of Central
rate of heart ↑ kidney and skin↑ sweat gland nerve
myocardial secretion system
excitation
contractility ↑ ↑
Peripheral resistance
Skin
↑ Renal
Ischemia Ischemia
dysphoria
Precapillary
sphincter arteriole
后微动脉
postarteriole
features :
Precapillary resistance(vasodilation) less than
postcapillary resistance (vasoconstriction)
opening capillary↑
more perfusion and less flow
2. The Mechanism of Microcirculatory Stasis
hydrogen ion↑
Precapillary resistance(vasodilation) <
Histamine↑
postcapillary resistance (vasoconstriction)
Kinin ↑
and so on Blood stagnation
Fluid ooze↑
Venous return↓
↑
cardiac output↓↓
Hypotension hypoxia
3.The Effects of Microcirculatory
Stasis
1)Decompensation:
① Return heart blood volume↓( Aut-blood-transfusion
Peripheral
resistance↓ Return heart blood
volume ↓
Precapillary
sphincter arteriole
后微动脉
postarteriole
features :
Microcirculatory vessele paralysis dilation
Microthrombosis
mechanisms :
Ischemia
Barrier function Endotoxin enter blood
Stasis
endotoxemia
hepatic detoxification↓
5. The Changs of Brain Function