knowing about 9/19/2014 sanshray13.blogspot.com 1 Presentation Upper gi bleeding : Above the ligament of treitz or above the duodenojejunal flexure Manifested in the form of hematemesis or malena Lower gi bleeding Below the ligament of treitz Manifested in the form of hematochezia 9/19/2014 sanshray13.blogspot.com 2 Ligament of treitz 9/19/2014 sanshray13.blogspot.com 3 Common causes of upper gi bleeding Peptic ulcer Bleeding oesophageal varices Gastroduodenal erosions Erosive oesophagitis Mallory Weiss tear Malignancy Vascular ectasias No cause found 9/19/2014 sanshray13.blogspot.com 4 Vomiting due to GI bleeding or due to some other causes ? It is important to differentiate whether the bleeding is due to GI bleeding or some other causes like hemoptysis or epistaxis. Ask if the patient had bleeding from the nose before vomiting of blood. Ask for cough preceding the vomiting of blood. 9/19/2014 sanshray13.blogspot.com 5 How to differentiate the different causes of gi bleeding Peptic ulcer The patient gives a history of burning or gnawing abdominal pain which is worsened by intake of food or which awakens the patient at night. There is history of nausea,belching and unintentional weight loss Bleeding oesophageal varices May present with other signs of decompensated cirrhosis such as ascites , hepatic encephalopathy , jaundice 9/19/2014 sanshray13.blogspot.com 6 Erosive oesophagitis : There may be history of burning sensation in the chest overlying oesophagus There may be h/o dysphagia ( difficulty in swallowing ) Mallory Weiss tear Typical h/o retching before vomiting 9/19/2014 sanshray13.blogspot.com 7 Management of upper gi bleeding The first and foremost thing is resuscitation Fluid resuscitation by ringer lactate or normal saline through a wide bore cannula (16 G) Insertion of nasogastric tube to decompress the stomach Aspirate the blood to know the probable site of bleeding Insertion of Foley's catheter to monitor the urine output Send the blood for hemoglobin , hematocrit ,Rh typing , blood grouping and cross matching If the hemoglobin or hematocrit comes out to be very low prepare for blood transfusion with packed RBC. In the mean time we can access the blood loss which can be done as follows 15-20 % = no symptoms 20-40 % = tachycardia and hypotension >40 % = shock
9/19/2014 sanshray13.blogspot.com 8 Management continued Send for LFT (liver function test) in patients who are suspected to have cirrhosis
Start the patient on PPI Pantoprazole 80 mg bolus followed by 8mg/hr for 48-72 hours Do an endoscopy to locate the site of bleeding If the bleeding is from a peptic ulcer and is profusely bleeding Sclerotherapy with adrenaline (1:10000) can be given endoscopically Use a hemostat clip to stop the bleeding endoscopically If the ulcer is due to H.pylori then start the patient on anti H.pylori triple therapy regimen .
9/19/2014 sanshray13.blogspot.com 9 Management continued. If the bleeding is due to bleeding varices then : rubber band ligation of the varices can be done Sclerotherapy can also be done Octreotide 50 g iv bolus followed by 50 g/h can be given if above measures fail to control the bleeding then TIPS ( Transjugular Intrahepatic Portosystemic Shunting ) should be considered In cases where the endoscopic procedure is not available compression of varices with Sengstaken Blackmore tube can be done although it is not a primary choice of procedure.
9/19/2014 sanshray13.blogspot.com 10 Case A 4o years old gentleman with significant alcohol intake history was brought to the emergency dept. with H/o vomiting of blood. What are the common causes of hematemesis? How will you manage this patient ? 9/19/2014 sanshray13.blogspot.com 11