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Lanjutan hal. 3
112 patients a first-time diagnosis of mania
or hypomania
42% diagnosed with bipolar I disorder,
13% diagnosed with bipolar II disorder
45% there were not sufficient data to
distinguish between the two types.
2/112 cases
diagnosis was acquired from a foreign
colleague after admittance to a psychiatric
hospital abroad
was based on a diagnosis by a GP (ICPC)
combined with an accurate description of the
episode followed by referral and treatment.
(Fig. 2)
Urbanization
The incidence of bipolar disorder was not different in
urban compared to non-urban areas,
0.74/10000 PY in the urban areas
(95% CI: 0.560.95) and
0.65/10000 PY in the non-urban areas
(95% CI: 0.420.97)
The difference between the two urbanization
categories was not statistically significant when
bipolar I and II disorder were considered separately
(Fig. 3).
Deprivation
The overall incidence of (hypo)mania was
statistically significant higher (p = 0.0012) in
deprived areas
[1.52/10000 PY (95% CI: 0.852.51)] (Fig. 4A)
compared to non-deprived areas
[0.64/10000 PY (95% CI: 0.520.78)],
which was mainly due to a higher incidence of
bipolar I disorder in deprived areas (Fig. 4B).
Discussion
The present study shows that the IR of bipolar
disorder in the general population of the
Netherlands is 0.7/10000 PY,
with a peak incidence in early adulthood (ages
1524 years) and a larger peak at ages 4554
years.
The results also suggest that the IR of bipolar I
disorder is higher in deprived areas compared
to non-deprived areas.