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DEFINITION
Static
leukomalacia)
remains a major problem reflect the
enhanced vulnerability of immature brain
to oxidative stress caused by ischemia
CLINICAL MANIFESTATION
CP
Classification of CP
Motor
Syndromes
Neuropathology
Major causes
Spastic diplegia
PVL
Prematurity
Ischemia
Infection
Endocrine/metabolics (e.g.
thyroid)
Spastic
quadriplegia
PVL
Multicystic
encephalomalacia
Malformations
Ischemia
Infection
Endocrine/metabolics (e.g.
thyroid)
Genetic/developmental
Classification of CP
Motor
Syndromes
Neuropathology
Major causes
Hemiplegia
Stroke: in utero or
neonatal
Trombophilic disorder
Infection
Genetic/developmental
Periventricular hemorhage
infarction
Asphyxia
Extrapyramidal
(athetoid,
dyskinetic)
Basal ganglia
Pathology: putamen,
globus pallidus,
thalamus
Kernicterus
Mitochondrial
Genetic/metabolic
CLINICAL MANIFESTATION
Spastic
hemiplegy:
CLINICAL MANIFESTATION
Spastic
diplegy:
CLINICAL MANIFESTATION
Spastic
quadriplegy:
CLINICAL MANIFESTATION
Athetoid
CP / Extrapiramidal CP:
DIAGNOSIS
A
TREATMENT
A