PowerPoint Lecture Slides prepared by Vince Austin, University of Kentucky

Cells: The Living Units

Part C

Human Anatomy & Physiology, Sixth Edition

Elaine N. Marieb
Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Golgi Apparatus

Stacked and flattened membranous sacs

Functions in modification, concentration, and
packaging of proteins
Transport vessels from the ER fuse with the cis face
of the Golgi apparatus
Proteins then pass through the Golgi apparatus to the
trans face
Secretory vesicles leave the trans face of the Golgi
stack and move to designated parts of the cell
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Golgi Apparatus

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Figure 3.20a

Role of the Golgi Apparatus

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Figure 3.21

Lysosomes

Spherical membranous bags containing digestive

enzymes
Digest ingested bacteria, viruses, and toxins
Degrade nonfunctional organelles
Breakdown glycogen and release thyroid hormone
Breakdown nonuseful tissue
Breakdown bone to release Ca2+
Secretory lysosomes are found in white blood cells,
immune cells, and melanocytes
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Endomembrane System

System of organelles that function to:

Produce, store, and export biological molecules
Degrade potentially harmful substances

System includes:
Nuclear envelope, smooth and rough ER,
lysosomes, vacuoles, transport vesicles, Golgi
apparatus, and the plasma membrane
PLAY

Endomembrane System

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Endomembrane System

Figure 3.23
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Peroxisomes

Membranous sacs containing oxidases and catalases

Detoxify harmful or toxic substances
Neutralize dangerous free radicals
Free radicals highly reactive chemicals with
unpaired electrons (i.e., O2)

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Cytoskeleton

The skeleton of the cell

Dynamic, elaborate series of rods running through
the cytosol
Consists of microtubules, microfilaments, and
intermediate filaments

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Cytoskeleton

Figure 3.24
Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Microtubules

Dynamic, hollow tubes made of the spherical protein

tubulin
Determine the overall shape of the cell and
distribution of organelles

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Microfilaments

Dynamic strands of the protein actin

Attached to the cytoplasmic side of the plasma
membrane
Braces and strengthens the cell surface
Attach to CAMs and function in endocytosis and
exocytosis

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Intermediate Filaments

Tough, insoluble protein fibers with high tensile

strength
Resist pulling forces on the cell and help form
desmosomes

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Motor Molecules

Protein complexes that function in motility

Powered by ATP
Attach to receptors on organelles

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Motor Molecules

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Figure 3.25a

Motor Molecules

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Figure 3.25b

Centrioles

Small barrel-shaped organelles located in the

centrosome near the nucleus
Pinwheel array of nine triplets of microtubules
Organize mitotic spindle during mitosis
Form the bases of cilia and flagella

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Centrioles

Figure 3.26a, b
Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Cilia

Whiplike, motile cellular extensions on exposed

surfaces of certain cells
Move substances in one direction across cell
surfaces

PLAY

Cilia and Flagella

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Cilia

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Figure 3.27a

Cilia

Figure 3.27b
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Cilia

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Figure 3.27c

Nucleus

Contains nuclear envelope, nucleoli, chromatin, and

distinct compartments rich in specific protein sets
Gene-containing control center of the cell
Contains the genetic library with blueprints for
nearly all cellular proteins
Dictates the kinds and amounts of proteins to be
synthesized
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Nucleus

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Figure 3.28a

Nuclear Envelope

Selectively permeable double membrane barrier

containing pores
Encloses jellylike nucleoplasm, which contains
essential solutes
Outer membrane is continuous with the rough ER
and is studded with ribosomes
Inner membrane is lined with the nuclear lamina,
which maintains the shape of the nucleus
Pore complex regulates transport of large molecules
into and out of the nucleus
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Nucleoli

Dark-staining spherical bodies within the nucleus

Site of ribosome production

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Chromatin

Threadlike strands
of DNA and
histones
Arranged in
fundamental units
called nucleosomes
Form condensed,
barlike bodies of
chromosomes when
the nucleus starts to
divide
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Figure 3.29

Cell Cycle

Interphase
Growth (G1),
synthesis (S),
growth (G2)

Mitotic phase
Mitosis and
cytokinesis
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Figure 3.30

Interphase

G1 (gap 1) metabolic activity and vigorous growth

G0 cells that permanently cease dividing
S (synthetic) DNA replication
G2 (gap 2) preparation for division

PLAY

Late Interphase

Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings