Documente Academic
Documente Profesional
Documente Cultură
Syakirah
Izzah
Rabi`atul
What is Digestion?
Digestion is a catabolic process in
which large complex molecules
(carbohydrates,
lipids,
proteins,
nucleic acids) are broken down into
simpler
monomers
(monosaccharides, glycerol and fatty
acids, amino acids, and nucleotides)
which can be absorbed by the body.
Function
Types of Digestion
Proses Pencernaan
4.
5.
6.
Chemical Digestion
Absorption
Defecation
Proses Pencernaan
Saliva:
Mixture of mucus and serous fluids
Helps to form a food bolus
Contains salivary amylase to begin starch
digestion
Dissolves chemicals so they can be tasted
Teeth (Ac)
Permanent teeth
Replace deciduous teeth
beginning between the ages
of 6 to 12
A full set is 32 teeth, but
some people do not have
wisdom teeth
Types of teeth:
Incisors - cutting
Canines - tearing
Premolars shearing,
shredding
Molars - grinding
Tooth Structure
Crown exposed part
Outer enamel
Dentin
Pulp cavity
Neck
Region in contact with
the gum
Connects crown to root
Root
Periodontal membrane
attached to the bone
Root canal carrying blood
vessels and nerves
Pharynx (Al)
Serves as a passageway
for air and food
Food is propelled to the
esophagus by two
muscle layers
Longitudinal inner layer
Circular outer layer
Food movement is by
alternating contractions
of the muscle layers
(peristalsis)
Esophagus (Al)
Runs from pharynx to stomach
through the diaphragm
Conducts food by peristalsis
(slow rhythmic squeezing)
Passageway for food only (respiratory
system branches off after the
pharynx)
Stomach
Stomach (Al)
Located on the left side of the abdominal cavity
Food enters at the cardioesophageal sphincter
Regions of the stomach
Function of Stomach
Acts as a storage
tank for food
Site of food
breakdown
Chemical
breakdown of
protein begins
Delivers chyme
(processed food) to
the small intestine
Pancreas (Ac)
Produces a wide spectrum of digestive
enzymes that break down all categories
of food
Enzymes are secreted into the
duodenum
Alkaline fluid introduced with enzymes
neutralizes acidic chyme
Endocrine products of pancreas
Insulin
Glucagon
Colon
Ascending
Transverse
Descending
S-shaped sigmoidal
Rectum
Anus external body
opening
DIGESTION OF NUTRIENT
WHAT IS NUTRIENT?
Substance in food that is used by the
body to promote normal
growth ,maintenance and repair.
Divide into 6 categories
major
nutrient:carbohydrate,lipids,water
and
protein
minor nutrient:vitamin and mineral
WHAT IS DIGESTION?
Process of breaking down ingested food
into small molecule
For example:
-In mouth,salivary amylase convert
starch to maltose,maltotriose and a-dextrin
-In stomach,pepsin convert protein to
peptide
-Lingual and gastric lipases convert
triglycerides into fatty acid,diglycerides
and monoglycerides
DIGESTION OF
CARBOHYDRATE
Salivary amylase keep continue in
stomach but then it was stop by acidic
pH. So, just a few starches are broken
down
Starches that not already broken down
into maltose,maltotriose and a-dextrins
are cleaved by pancreatic amylase
Although pancreatic amylase acts
both on glycogen and starches but it
doesnt effect cellulose
DIGESTION OF PROTEIN
Protein are fragmented into peptide by
action of pepsin
Enzyme in pancreatic juicetrypsin,chymotrypsin,carboxypeptid
ase and elastase-continue to break
down protein into peptide
Although all these enzyme convert whole
protein into peptide,their action differ
somewhere bcoz each split peptide
bonds between different amino acid
DIGESTION OF LIPIDS
The most abundant lipids in diet are
triglycerides,consist of molecule of glycerol
bonded to three fatty acid molecule
Enzyme that split triglycerides and
phospholipids are called lipase
Three type of lipases that can participate
in lipid digestion are lingual lipase,gastric
lipase and pancreatic lipase
DIGESTION OF NUCLEIC
ACID
Pancreatic juice contain two
nucleases:ribonuclease which digest
RNA and deoxyribonuclease which
digest DNA
Result of the action of this two nuclease
are further digested by nucleosidases
and phosphatase into
pentose,phosphates and nitrogenous base
These product are absorbed via active
tansport
ABSORPTION
WHAT IS ABSORPTION?
Passage of digested nutrients
from gastrointestinal tract
into the blood or lymph
ABSORPTION OF
MONOSACCHARIDES
The capacity of small intestine to
absorb monosaccharide is huge-an
estimated 120 grams per hour
As a result, all dietary carbohydrate
that are digested normally are
absorbed, leaving only indigestible
cellulose and fiber in feces.
Monosaccharides pass from the lumen
through the apical membrane via
facilitated diffusion or active transport.
ABSORPTION OF AMINO
ACIDS,DIPEPTIDES AND
TRIPEPTIDES
ABSORPTION OF LIPID
All dietary lipid are absorbed via simple
diffusion
Because of emulsification and digestion;
triglycerides are mainly broken down into
monoglycerides and fatty acid, which can be
short-chain fatty acid or long-chain fatty acid
Short-chain fatty acid are hydrophopic and
small in size. Thus, they can dissolve in the
watery instestinal chyme,pass through the
absorptive cells via simple diffusion
ABSORPTION OF
ELECTROLYTE
Electrolyte that are absorbed by the
small intestine come from
gastrointestinal secretions and some
are part of ingested foods and liquids
Recall that electrolyte are compound
that separate into ions in water and
conduct electricity
ABSORPTION OF VITAMINS
Fat soluble vitamin A,D,E and K are
included with digested dietary lipid
and absorbed via simple diffusion
Water-soluble vitamin such as B and
C also absorbed via simple diffusion.
However B12 combine with intrinsic
factor produced by the stomach and
combination is absorbed in the ileum
via an active transport mechanism
ABSORPTION OF WATER
the total volume of fluid that enter small
intestine each day about 9.3 liters-comes
from ingestion of liquid and from various
gastrointestinal secretion
The small intestine absorbs about 8.3 liters of
fluid; the remainder passes into the large
intestine, where most of the rest of it-about
0.9 liter
Only 0.1 liter of water is excreted in the feces
each day. Most is excreted via urinary sytem
METABOLISMA
Metabolisma
Tindak balas kimiayang berlaku
dalamselhidup yang membolehkan sel
membesar dan membiak dan mengekalkan
struktur mereka.
Dibahagikan kepada dua jenis :
1)Katabolisme: menghasilkan tenaga, seperti
pemecahan makanan dalamrepirasi sel.
1)Anabolisme : memenggunakan tenaga
untuk membentuk komponen sel
sepertiproteindanasid nukleik.
Laluan Metabolik
Metabolisma karbohidrat
Tdpt 3 jenis kmpln utama karbohidrat iaitu :
a) Monosakarida gula ringkas : glukosa
b) Disakarida gula kompleks : maltosa
c) Polisakarida gula kompleks y bsr : kanji,glikogen
Laluan ini melibatkanpemecahan molekul-molekul
karbohidratdi dalam organ hati, kerana hati menyimpan
glukos.
Glukosa merupakan monosakarida yang paling penting
dalam metabolisme tubuh.
Glukosa yang terkandung dalam nutrisi masuk ke dalam
sistem sirkulasi atau ke dalam darah untuk dipindah ke selsel tubuh yang memerlukannya atau diubah pada hati
menjadi molekul yang lain.
METABOLISMA LIPID
Lipid
METABOLISMA PROTEIN
Protein adalah molekul-molekul y bsr &
kompleks.
Monomer bgi protein adlh asid amino.
Selbadan akn mengeluarkanasid
aminodaripada
darahdanmenggunakannyauntuk membina
protein,untuk kegunaan sendiri(enzymes,
membranes, muscle protein) dan untuk
mengeksport(mucus,hormones).
ATPakan tbentuk jikaglukosadanlemaktidak
mencukupiatau jikakekurangan Asidamino.
Asid nukleik yang biasa termasuk asid deoksiribonukleik (DNA) dan asid
ribonukleik (RNA). Asid nukleik terdapat dalam semua benda hidup,
kerana mereka terkandung dalam segala sel. Asid nukleik juga terdapat di
dalam virus.
mekanisme,anabolikumumnyamelibatkantindak balas
kimiafosfat,gulapentose,danasasbernitrogen.
Pemusnahanasid nukleikadalah
prosedurkatabolikumumnyamelibatkantindak balasenzim.
Kumpulan Makanan
Asas
Fungsi
Kesan
berlebihan
Kesan
kekurangan
Karbohidrat
Membekalkan tenaga
lebihan berat
utama untuk keperluan badan
badan
Marasmus(ptumb
uhan tbantut)
Protein
membentuk dan
membaiki tisu,
membentuk enzim,
antibodi, hormon,
agen pengangkut
lemak mningkat,
paras kalsium drh
tjejas
penghasilan
antibodi menurun
& risiko jangkitan
meningkat.
Penyakit
Kwasyiokor
Lemak
membekalkan tenaga
& pengekalan suhu,
membekalkan asid
lemak perlu,
penyerapan vitamin
larut lemak
lebihan berat
badan
Kekurangan berat
badan
Garam Galian
Dibahagikan kpd 2 kumpulan :
- Makronutrien (dplukan dlm Kuantiti bsr)
- Mikronutrien (dplukan dlm kuantiti kecil)
Makronutri
en
sumber
fungsi
Kesan
kekurangan
Kalsium
susu, keju,
ikan bilis,
bijirin
riket,osteopor
osis,
pdarahan
bpnjangan.
Magnesium
Bijirin,syrn
hijau,susu,
daging
Otot lemah
Susu,
daging,
pisang,
sayuran
hijau
Ganguan dlm
sstm saraf
Fosforus
Susu,
daging,
bijirin, telur
Tulang rapuh,
kerosakan
gigi.
Natrium
Garam,
daging,
Kekejangan
otot
kalium
Mikronutrien
sumber
Fungsi
Kesan
kekurangan
Iodin
Udang, kerang,
makanan laut
Mbntk hormon
tiroksina
Goiter, kretinisme
pd knk-knk
Besi
Hati, bayam,
kacang, telur
kuning
Mbntk
hemoglobin
Anemia
Florin
Karies gigi
Vitamin
Kumpulan sebatian organik yang diperlukan dalam
kuantiti yang kecil untuk memelihara dan mengekalkan
kesihatan.
Dikelaskan kepada 2 kumpulan :
a) Larut lemak:
- tidak dapat dikumuh melalui air kencing tetapi
disimpan dalam badan
- vitamin A, D, E dan K.
a) Larut air:
- tidak dapat disimpan dalam badan dan sebarang
kuantiti berlebihan akan larut dalam air dan
dikumuhkan keluar melalui air kencing.
- Vitamin B kompleks dan vitamin C.
jenis
sumber
fungsi
Kesan
kekurangan
Vitamin
C
buah-buahan.
skurvi ( gusi
bdarah, kulit
lebam, sendi
bgkak)
Vitamin
D
Vitamin
E
sayuran
hijau,minyak kelapa
sawit.
kemorosotan
otot & saraf
Vitamin
K
hati,bayam dan
kubis.
bdarah secara
berlebihan
Vitamin
A
rabun malam,
kulit tidak
yang sihat
Air
Merupakan 70% drp berat bdn manusia.
Peranan :
a)Sbg pelarut
b)Medium tndk bls kimia dlm bdn.
c)Medium pengangkutan bhn mknn tcerna,
oksigen, bhn pkumuhan.
d)Pengawalaturan suhu bdn : Bila kekurangan air,
suhu tubuh akan menjadi panas dan naik.
Khdiran air akan mbntu mstabilkan suhu bdn.
e)Sbg pelincir : mngurangkan geseran tulang pd
sendi.
f) Pkumuhan : urea,asid urik & grm mineral
blebihan dsingkirkn melalui air kencing dan
peluh.
TENAGA
Pengukuran Tenaga
1. Kalori: Jumlah tenaga haba yang
diperlukan untuk menaikkan suhu satu gram
air sebanyak satu darjah celsius.
2. Kilokalori (Kcal)
Jumlah haba yang diperlukan untuk
meningkatkan suhu 1 kg. air sebanyak
sebanyak 1 darjah celsius.
3. Unit metrik yang digunakan ialah kilojoule(KJ)
1 Kilokalori (Kcal) = 4.184 KJ)
84
Contoh Pengiraan 1
Berapakah nilai tenaga yang dalam satu gelas susu
beratnya 244g ? Jika dalam susu 100g susu
mengandungi:
4.9g CHO; 3.5g protein; 3.7g lemak; 0.6 mineral dan
1.2g vitamin
CHO
=244/100 x 4.9g x 4kcal = 47.8 kcal
Protein =
244/100 x 3.5g x 4kcal = 34.2
kcal
Lemak = 244/100 x 3.7g x 9kcal = 81.3 kcal
Jumlah nilai tenaga
= 163.3 kcal
86
Contoh pengiraan 2
87
a.
Jumlah g protein
= 840 kcal
= 1080 kcal
= 280 kcal
70 g
38.2%
49.1%
12.7%
88
Soalan:
1. Potato crisps mengandungi 6.3 g protein, 35.9g lemak
89
90
Input Tenaga
Tenaga/kilokalori yang terdapat dalam makanan
Output Tenaga
Tenaga yang diperlukan @ digunakan
oleh tubuh untuk beberapa perkara:
Kadar Metabolisme Asas [Basal Energy
Rate]
Aktiviti Fizikal
Pertumbuhan
Tindakan Spesifik Dinamik Makanan
91
92
1. Menggunakan anggaran 1
kilokalori/minit
=
60 m/jam X 24jam/hari
=
1440 kilokalori/hari
96
3.
Lelaki
< 50 tahun
> 50 tahun
Wanita
< 50 tahun
> 50 tahun
Contoh:
Kira berapakah jumlah tenaga untuk KMA dalam
sehari bagi mereka yang berikut?
a. En. Adam berumur 45 tahun mempunyai berat
badan 65 kg
Keperluan tenaga KMA = 1 x 65 x 24 jam
= 1560 kcal
b. Cik Fatimah berumur 26 tahun mempunyai berat
badan 46 kg.
Keperluan tenaga KMA = 0.9 x 46 x 24 jam
= 993.6 kcal
99
Wanita
Berat dalam Kg x 0.95 kcal x 24 jam
Lelaki
Berat dalam Kg x 1.0 kcal x 24 jam
Contoh:
Aminah berumur 13 tahun dan berat badan 50 kg.
50kg x 0.95 kcal x 24 jam =
1140 Kcal
103
3-9
10-17
22.5w +
499
12.2w + 746
18-29
14.7w + 496
30-60
8.7w + 829
> 60
10.5w + 596
104
Latihan:
1. Aminah mempunyai berat badan 50 kg. , berumur 18
tahun . Kirakan keperluan tenaga Aminah dalam sehari
dengan menggunakan Formula REE ?
= 14.7 w + 496
= ( 14.7 x 50 ) + 496
= 735 + 496
= 1231 kcal/hari
2. Hamid mempunyai berat badan 78kg dan berumur 33
tahun. Kirakan keperluan tenaga dengan Formula
REE?
105
1. Komposisi tubuh
-
106
2.
3.
4.
5.
6.
7.
8.
9.
10. Umur:
Umur meningkat keperluan KMA menurun
11. Merokok: lebih 10 peratus daripada orang tidak merokok
108
Soalan:
Norzalina 25 tahun, tinggi 1.63 m dan berat badan
65 kg. Berikut adalah jumlah kalori yang dimakan iaitu
karbohidrat 190g; protein 120g dan lemak 93g mengikut
24-jam dietary recallnya.
a.
b.
109
(i)
a.
b.
c.
karbohidrat
protein
lemak
=
=
=
190 X 4 kcal
120 X 4 kcal
93 X 9 kcal
Jumlah
= 760 kcal
= 480kcal
= 837 kcal
= 2077kcal
karbohidrat
protein
lemak
=
=
=
760/2077 X 100
480/2077 X 100
837 /2077 X 100
= 36.6 %
= 23.1 %
= 40.3%
110
i.
[2077 1482]
112
Menu 3000-4000kcal
113
Menu 4000-5000kcal
114
Menu 5000-6000kcal
115
Slide
Digestive Homeostasis
Disorders
ULCERS erosion of the surface of
the alimentary canal generally
associated with some kind of
irritant
Digestive Homeostasis
Disorders
CONSTIPATION a
condition in which the
large intestine is
emptied with
difficulty.
Too much water is
reabsorbed
and the solid waste
hardens
Digestive Homeostasis
Disorders
DIARRHEA a gastrointestinal
disturbance characterized by
decreased water absorption
and increased peristaltic
activity of the large intestine.
This results in increased,
multiple, watery feces.
This condition may result in
severe dehydration,
especially in infants
Digestive Homeostasis
Disorders
APPENDICITIS an inflammation of
the appendix due to infection
Common treatment is removal of the
appendix via surgery
Digestive Homeostasis
Disorders
GALLSTONES an accumulation of
hardened cholesterol and/or
calcium deposits in the gallbladder
Can either be passed (OUCH!!)
or surgically removed
Digestive Homeostasis
Disorders
Digestive Homeostasis
Disorders
HEART BURN ACID from the
stomach backs up into the
esophagus.
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