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What is a Virus?
A virus is a noncellular particle made up of
genetic material and protein that can
invade living cells
Structure
Core of nucleic acid surrounded by a protein
coat called a capsid
Capsid can be DNA or RNA, but not both
Core can be several to several hundred genes
Bacteriophage
Bacteriophages are viruses that infect
bacteria
Bacteriophage
Head capsid and DNA
Tail with fibers to attach to bacteria
T group
Most commonly studied are T group T1,
T2, T3, T4 etc...
T4 has a DNA core within a protein coat,
and tail with tail fibers to attach to bacteria.
Viral shapes
Variety of shapes
Rod
Tadpole
Many sided, helical or cubelike
VIRUS SHAPES
Round
Rod-shaped
Many sided
(icosohedral)
T4 Bacteriophage
Head
DNA
Influenza
Virus
RNA
Capsid
proteins
Capsid
RNA
Tail
sheath
Tail
fiber
Surface
proteins
Membrane
envelope
ROUND VIRUSES
Herpes virus
There are
two types:
Genital
oral
ROD-SHAPED
Tobacco
mosaic
virus
MANY SIDED
bacteriophage
E coli bacteria
Virus Size
Size 20 to 400 nanometers (one
nanometer is one billionth of a meter)
Specificity usually infect specific
organisms
Cannot infect animals if it infects plants
Some can infect wider variety
Rabies all mammals, some birds
Lytic Infection
Bacteriophage DNA
Bacterial
chromosome
Bacteriophage attaches to
bacteriums cell wall
Bacteriophage enzyme lyses the
bacteriums cell wall, releasing
new bacteriophage particles that
can attack other cells.
Lytic Cycle
Bacteriophage injects DNA
into bacterium
Bacteriophage
Bacteriophage DNA
Bacteriophage protein
Retroviruses
RNA viruses
When they infect a cell, they produce DNA copies
of their RNA genes.
Retroviruses have their genetic information copied
backwards. RNA DNA
One retrovirus is HIV. Others cause cancer in
animals and humans.
The theory is that viruses were not the first living
things. They are dependent on living things to
survive.
EUBACTERIA AND
ARCHAEBACTERIA:
The two bacterial
kingdoms
Bacteria on a pin head
Eubacteria
True bacteria
largest Kindgom of prokaryotes
generally surrounded by cell wall composed of
complex carbohydrates
have a cell membrane (some have 2 cell membranes)
Some have flagella for movement
Found everywhere
Some produce disease
Some photosynthetic
some very useful cheese is just one example
PROKARYOTIC CELLS
Prokaryote what does that mean?
Classification of Prokaryotes
All prokaryotes were in kingdom Monera.
Now 2 kingdoms
Eubacteria and archaebacteria
Archaebacteria
Archaebacteria includes organisms that
live in very harsh environments
Methanogens live in oxygen free
environments mud, digestive tracts of
animals
Extremely salty environments
Hot springs
Identifying Bacteria
Cell Shape
Rod bacilli
Sphere cocci
Spiral spirilla
Bacterial Shapes
Round
Rod
Spiral
Arrangement
2 cocci diplococci
long chains streptococci
clumps, clusters staphylococci
Cell Wall
Chemical nature Gram staining
Hans Christian Gram
2 dyes crystal violet (purple) and safranine (red)
bacteria either take one or the other
If only one thick layer of carbohydrate and protein
molecules outside the cell membrane picked up
crystal violet appeared purple GRAM POSITIVE
If cell had 2nd, outer layer of lipid and carbohydrate
picked up safranine appeared red GRAM NEGATIVE
Bacterial movement
propelled by flagella
lash, snake, or spiral forward
no movement
Bacterial Respiration
Obligate aerobes require oxygen
Obligate anaerobes must live in
absence of oxygen
example is Clostridium botulinum
Reproduction
Some can reproduce every 20 minutes
Held in check by food and production of wastes
Types:
Binary Fission
Replication of DNA and division in half
Asexual
Conjugation
Sexual involves the exchange of genetic material
Long bridge of protein forms between the cells
Donor genetic information transferred to recipient through
bridge
Recipient cell has different genes at the end than it did to
begin with
Importance of Bacteria
Symbiotic Relationships
(mutuallism)
E. coli in humans help us digest food
make vitamins we cant, we give them a
home, food, and transportation
Bacteria in the intestines of cattle allow
them to break down cellulose (in grass
and hay)
Sewage decomposition
Sewage treatment bacteria is added
directly to the raw sewage
How does a septic tank work?
Nitrogen Fixation
All organisms are TOTALLY dependent on
monerans for Nitrogen
All Plants need nitrogen to make amino acids (NH2)
Because animals eat plants, they get their
proteins from plants
What percentage of the air is Nitrogen?
Plants, and most other organisms cannot use
this directly
Need Nitrogen to be FIXED chemically as
ammonia
Nitrogen Fixation
Scientists can make synthetic nitrogen containing
fertilizers by mixing Nitrogen and Hydrogen gases,
heating to 500 degrees C and compressing it to 300 X
normal atmospheric pressure dangerous, expensive,
time consuming
Many cyanobacteria can take nitrogen from the air and
convert it to a useable form this is called Nitrogen
Fixation
Bacteria are the only organisms that can do this.
Some plants have a symbiotic relationship with nitrogen
fixing bacteria
soybean Rhizobium grows in nodules around roots
Small Pox
Polio
Measles
AIDS
Mumps
Influenza
Yellow Fever
Rabies
Common Cold
Ebola etc
Vaccine
The bodys own defenses must be used
Vaccine dead or weakened viruses that
stimulate the bodies defense system
Symptoms can be treated sometimes, but
once someone is infected by a virus, there
is not much science can do