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A N EM IA D EFIS IEN S I FE
D A N PA LLO R
Pallor or pale
Is a change of skin color to become pale
is a reduced amount of oxyhaemoglobin
Possible causes
Anemia
Shock, cardiogenic shock or
hemorrhagic shock
Migraine attack or headache
Hypoglycemia
Frostbite
Hypothyroidism
Emotional responses
Exam ination
Exam ination
Anem ia
Anemia is most often recognized by abnormal
petechiae.
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suggest an underlying
lymphoproliferative disease
while petechiae suggest platelet
dysfunction
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Specifi
c blood test for anem ia
II. Iron supply studies
A. Serum iron
B. Total iron-binding capacity
C. Serum ferritin
Iron defi
ciency anem ia
Iron is a critical element in the function of all
120 days. Thus, 0.81.0% of red cells turn over each day.
At the end of its life span, the red cell is recognized as
senescent by the cells of the reticuloendothelial (RE)
system, and the cell undergoes phagocytosis.
Once within the RE cell, the hemoglobin from the
ingested red cell is broken down, the globin and other
proteins are returned to the amino acid pool, and the iron
is shuttled back to the surface of the RE cell, where it is
presented to circulating transferrin.
It is the efficient and highly conserved recycling of iron
from senescent red cells that supports steady state (and
even mildly accelerated) erythropoiesis
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Normal smear
D iff
erentialdiagnosis ofanem ia m ikrositik
D iff
erentialdiagnosis anem ia hipoproliferatif
Iron-D efi
ciency Anem ia:Treatm ent
The severity and cause of iron-deficiency anemia
Red CellTransfusion
Transfusion therapy is reserved for
O ralIron Therapy
iron replacement therapy, up to 300 mg of
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