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Ferawati
BACKGROUND
BACKGROUND
BACKGROUND
BACKGROUND
BACKGROUND
The greatest predictable risk factors for progression of
BPH are:
Age older than 50,
Moderate prostate symptoms (IPSS 8), and
Prostate volume greater than 30 cc (or PSA 1,5
ng/mL, where PSA is a surrogate marker for prostate
volume)
BACKGROUND
The following parameters are signs of BPH progression:
Change in symptoms score (IPSS),
Increase in postvoid residual (PVR) urine volume,
Recurrent urinary tract infection,
Hematuria,
Renal failure,
Onset of urinary retention
The need for surgery
MANAGEMENT OF BPH
LIFESTYLE MODIFICATION
LIFESTYLE MODIFICATION
LIFESTYLE MODIFICATION
ALPHA BLOCKERS
ALPHA BLOCKERS
ALPHA BLOCKERS
These drug relieve LUTS through three proposed
mechanisms:
Relaxation of the smooth muscle tone in the prostate
stroma and bladder neck
Relaxation of bladder smooth muscle
Action on the central nervous system
In the most men, treatment with alpha blocker
provides fairly fast symptoms relieve (48 hours to 1
weeks), 30-50% improvement in symptoms compared
to plasebo
ALPHA BLOCKERS
COMBINATION THERAPY
COMBINATION THERAPY
COMBINATION THERAPY
COMBINATION THERAPY
COMBINATION THERAPY
COMBINATION THERAPY
COMBINATION THERAPY
COMBINATION THERAPY
COMBINATION THERAPY
COMBINATION THERAPY
CONCLUSION
CONCLUSION