APPLICATION OF SPSS

Rajat Kumar, M.Pharm (Pceutics)

NIET Gtr. Noida

INTRODUCTION

SPSS is a software package used for conducting statistical analysis,

manipulating data, and generating table and graphs that summarize data.

SPSS performs statistical analysis range from basic descriptive statistics,

such as average and prevalence, to advanced inferential statistical, such
as regression model, analysis of variance (ANOVA), factor analysis etc.

SPSS also contains several tools for manipulating data, including functions
for recording data, macros programming on visual basic editor, merging
data, and aggregating complex data sets.

FEATURES AND BENEFITS

For Small And Medium Enterprises (SME)

Resources & best practices.

Techniques for cleaning data.

Access Data in Relational Databases.

For Large Scale Enterprises (LSE)

Real time processing and online mapping.

Online Database connectivity different networks.

Data import & export data from different medium like SAS, Statistica.

Compliances and Validations.

What are the options?

Many commercial products available

SAS, Statistica, Minitab, and others

Excel

Widely available (part of MS Office Suite)

Not a statistical software spreadsheet

Finance, math, and statistics applications

SPSS

Robust software for sophisticated statistical applications

Upgrade with add-ins

WHY SPSS?

Strengths

Very robust statistical software

Many complex statistical tests available

Good stats coach help with interpreting results

Easily and quickly displays data tables

Can be expanded

Using the syntax feature

Purchasing add-ins

Limitations

Can be expensive

Not intuitive to use

Typically requires additional training to maximize features (at a cost)

Graphing feature not as simple as Excel

RESEARCH & DEVELOPMENT

SPSS given the technique of specialize in design, development, and
implementation
of
corporate
analytical
and
data
mining
solution integrated with the existing data acquisition and storage
of systems. Its continuously given the solution in Pharmaceutical and
Medical research.

Quality and Manufacturing.

Compliance and Validation..

Empower Researcher with Tools.

Regulatory Safety Testing.

Clinical Trails.

Data Mining in Drug Discovery.

QUALITY AND MANUFACTURING

SPSS can provide a single, standardized quality control and
improvement solution that can be easily validated that cover the whole
range of manufacturing statistics, including simple descriptive
statistics and graphics, QC charting, capability analyses for normal
and Non-normal distributions, design of experiment (DOE) much
more.

Online and offline SPC (Statistical Process Control)

Process Capability Analysis.

Measurement System Analysis.

Design of Experiment

Process Validation.

COMPLIANCE AND VALIDATION

SPSS offers a pre-validation core platform with fully secure user
administration and configuration control, audit trails on system
configuration changes, data manipulation, analysis results and
integrated data modules.
Together these features can radically change the way of your
organization works and remove the need for extensive manual
documentation of analytical processes.

Validation of Software.

Analysis of Audit Trails.

Computer Systems Validation

EMPOWER RESEARCHER WITH TOOLS

Even small improvement in research and development process directly
affect an organizations bottom line and many pharmaceuticals research
organizations have experienced the positive impact of deploying SPSS.
Offering a choice of desktop (stand-alone), networks, and server based
analytical platforms.
Statistician has provided analytical tools that are easy to use, relevant and
integrated with their data sources.

Comprehensive Statistical Test & Graphical Tools.

Efficient use of limited Statistician & Training Resources.

Integrated with Existing System & Data Sources.

Rapid return on investment.

REGULATORY SAFETY TESTING

From simple bioassay and dose-response experiments to long-term
survival and carcinogenicity studies, SPSS has the tools to handle
your data. Where the standard study designed are used.
SPSS tools provides the most efficient mechanism for automating and
validating routine analysis report.

Power and Sample Size Calculation.

Predictive Data Mining.

Forecasting and Report Generation.

Analysis of Complex Drugs Assay.

CLINICAL TRIALS
Ethical considerations and at least in Phase I and Phase II Studies small
sample sizes make it imperative that the most power statistical
methods be used in ordered to established efficacy and detect side
effects.
SPSS is unique in providing a fully document management system
along with complete analytical toolkit. With ability to directly query
standard database platforms and to import a wide range of data file
format (including SAS files).

Generalized Linear and Non-Linear Model

Variance Component Estimations (ANOVA).

DATA MINING IN DRUG DISCOVERY

With the advent of new technologies that allow very large amounts of
data to be captured and stored automatically many new challenges
are presented.
In application of classical statistical methods many were developed
specially to extract the maximum amount of information from minimal
data sets.
According to the FDA Critical Path Initiative the use of data mining
technology and methodology is central to improvement discovery, preclinical and clinical research. SPSS perform a excellent crunch the
complex data sets.

Handle Huge Data Sets with Ease.

Exploratory Data Mining Techniques.

Comprehensive Data Mining Toolkit.

SUMMARY

Industry standard process

Open system

Easy to use graphic interface

Flexibility

Productivity