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HUMAN CELL
All living things are composed of cells.
Cells carry out thousands of biochemical reactions each
minute and reproduce new cells that perpetuate life.
Cells vary considerably in size.
red blood cells measure 0.00076 mm (0.00003 in) to
liver cells that may be ten times larger.
The human body, consists of an estimated 20 to 30
trillion cells.
displays a remarkable ability to join, communicate, and
coordinate with other cells.
the shape is typically tailored to the cell's job
pack tightly into a layer that protects the underlying tissues from
invasion by bacteria.
cells
Tissues
Connective tissue (tendons and bones)
Epithelial tissue (skin and mucous membranes)
Organs
Heart, Stomach, Brain, lungs
systems
Circulatory system
Digestive system
Nervous system
Respiratory system
Proteins
nucleic acids
Carbohydrates
lipids
Types of cells
unicellular,
meaning they consist of a single cell.
bacteria and protozoa,
multicellular
Eukaryotic cells
Multicellular
which make up plants, animals, fungi, and all other life forms,
contain numerous compartments, or organelles, within each cell.
The DNA in eukaryotic cells is enclosed in a special organelle
called the nucleus, which serves as the cell's command center
and information library.
eukaryote means true nucleus.
Cell Membrane
Structure
The Nucleus
The Nucleus
The nucleus is the largest, most
prominent organelle in eukaryotic cells;
it is a round or oval body that is
surrounded by the nuclear envelope and
contains the genetic information
necessary for control of cell structure and
function
Nucleolus
a small dark area inside the nucleus.
This dark area is called the
NUCLEOLUS.
The nucleolus is made up of protein and
RNA with very little DNA.
Chromatin
Francis Crick. He worked with Watson and Wilkins on figuring out the structure
of DNA.
He was born in England and then worked at Cambridge University. For his
work, he won a Nobel Prize in 1962.
The big deal about coming up with the structure was that scientists could figure
out how DNA duplicates.
Crick helped discover that DNA uses something called codons (sets of three
nucleic acids) when it duplicates and when it helps make proteins.
The Nucleotide
Conservative
Semi-conservative
dispersive.
The semi-conservative
model was proved to be
the correct one.
DNA polymerase
catalyzes the
synthesis of DNA
using a DNA strand
as a template.
B. Smooth Endoplasmic
reticulum (SER)
lacks ribosomes and has
an even surface.
Within the winding
channels of the smooth
endoplasmic reticulum are
the enzymes needed for
the construction of
molecules such as
carbohydrates and lipids.
The smooth endoplasmic
reticulum is prominent in
liver cells, where it also
serves to detoxify
substances such as
alcohol, drugs, and other
poisons.
Ribosomes
cells that produce many proteins for export,
white blood cells of the immune system,
which produce and secrete antibodies.
Ribosomes are the protein builders of the cell.
Ribosomes are found either floating around in
the CYTOPLASM or attached to the
Endoplasmic Reticulum (ER).
The ribosomes attached to the ER make
proteins that will be used inside the cell AND
sent outside the cell.
Ribosomes
The Lysosomes
These organelles also create something called ENZYMES
Enzymes are molecules that speed up chemical reactions.
Enzymes are the molecules used to break down large molecules.
Lysosomes combine with the food taken in by the cell.
The enzymes in the lysosome bond to the food and start to digest it.
Smaller molecules are released and they are absorbed by the
mitochondria.
Lysosomes also break down old organelles and cells.
When an organelle no longer works, the lysosome attaches and
breaks it down like food (kind of like a cannibal).
Lysosomes can also destroy the cell if it breaks open accidentally.
The Mitochondria
The Mitochondria
The POWERHOUSE of the cell
Mitochondria are very tiny organelles.
There can be several thousand
mitochondria in one cell, depending on
what the cell's job is.
That folding of the membrane
increases the SURFACE AREA.
The Mitochondria
Exocytosis
is the movement of
materials out of a cell
via membranous
vesicles.
A. Movement
Many unicellular organisms swim, glide, thrash,
or crawl to search for food and escape enemies.
Flagellum
the sperm cell uses a flagellum to swim toward the
female egg for fertilization
Cilia,
short, hairlike proteins built by centrioles, which are
barrel-shaped structures located in the cytoplasm that
assemble and break down protein filaments.
In cells that do not move, cilia are used for other
purposes.
In the respiratory tract of humans
ciliated cells prevent inhaled dust, smog, and microorganisms
from entering the lungs by sweeping them up on a current of
mucus into the throat, where they are swallowed.
B. Nutrition
C. Energy
Cells require energy for a variety of
functions, including moving, building up
and breaking down molecules, and
transporting substances across the
plasma membrane.
Nutrients contains energy, but cells must
convert the energy locked in nutrients to
another formspecifically, the ATP
molecule, the cell's energy battery
before it is useful.
D. Protein Synthesis
A typical cell must have on hand about
30,000 proteins at any one time.
Many of these proteins are enzymes needed
to construct the major molecules used by
cells
carbohydrates,
lipids,
proteins, and
nucleic acids
E. Cell Division
Most cells divide at some time during their life cycle, and some
divide dozens of times before they die.
Organisms rely on cell division for reproduction, growth, and
repair and replacement of damaged or worn out cells.
Three types of cell division occur:
binary fission,
mitosis, and
meiosis.
Binary fission
the method used by prokaryotes
produces two identical cells
from one cell.
MITOSIS
produces two genetically identical cells from a single cell
is used by many unicellular eukaryotic organisms for
reproduction.
Multicellular organisms use mitosis for growth, cell repair,
and cell replacement.
In the human body
Meiosis
The type of cell division required for sexual
reproduction.
Meiosis differs from mitosis in that cell division
begins with a cell that has a full complement of
chromosomes and ends with gamete cells, such
as sperm and eggs, that have only half the
complement of chromosomes.
When a sperm and egg unite during fertilization,
the cell resulting from the union, called a zygote,
contains the full number of chromosomes.
Mitosis
Meiosis
Mitosis
is division involved in development of
an adult organism from a single
fertilized egg,
in growth and repair of tissues, in
regeneration of body parts,
and in asexual reproduction.
the parent cell produces two "daughter
cells" that are genetically identical.
(The term "daughter cell" is
conventional, but does not indicate the
sex of the offspring cell.)
can occur in both diploid (2n) and
haploid (n) cells;
Meiosis
diploid parent cells divide and
produce the gametes or spores
that give rise to new individuals.
The parent cell produces four
haploid daughter cells.
cytoplasm
Prior to both mitosis and meiosis, the
chromosomes in the nucleus are
replicated.
The nucleus then divides.
Nuclear division is usually followed by
division of the cytoplasm.
In mitosis, there is one such division.
Meiosis consists of two divisions; since
the chromosomes have replicated only
once, the four daughter cells have half as
many chromosomes as the parent cell.
cell cycle
the orderly sequence of events that occurs
from the time a cell divides to form two
daughter cells to the time those daughter
cells divide again.
The phases of the cell cycle occur in
meiosis as well as mitosis
The length of time of the cell cycle varies
among organisms and among cell types..
INTERPHASE
Most of the cell cycle is spent
the cell is growing and metabolic activity
is very high.
Toward the end of interphase, new DNA is
synthesized and the chromosomes are
replicated.
Each chromosome of the homologous pair
is then composed of two sister chromatids.