Documente Academic
Documente Profesional
Documente Cultură
Nurpudji Astuti
Nutrition Department
School of Medicine
2003
Eating Disorders
Anorexia Nervosa
Bulimia Nervosa
Objectives
To understand the differences between
various eating disorders e.g. anorexia and
bulimia nervosa.
To consider causative factor presenting
features, at risk groups, medical
complications, prevention and treatment.
Eating Behaviors
Why do we eat?
Internal hunger
Energy external pleasure, social,
personality, environment
What is abnormal eating behavior?
Abnormal eating behavior = eating
disorder?
Eating behaviors
Why do we stop eating ?
We stop eating when we are satisfied?
Eating is a behavior Not necessarily
related to hunger or fullness
Introduction
Mr. Dukes daughter in S. Mary Axe, in the year 1684
and the eighteenth year of her age, In the month of July
fell into a total suppression of her monthly courses from
a multitude of cares and passions of her mind but
without any symptoms of the green-sickness following
upon itI do not remember that I did ever in my practice
see one, that was conversant with the living so much
wasted with the greatest degree of consumption ( like a
skeleton clad only in skin ) yet there was no feveronly
her appetite was diminishedshe was after three month
taken with a fainting-fit, and died
Hill et al.
41% of 9 year old girls choose a preferred body
shape thinner than their current shape (18%
chose broader)
41% of boys choose a broader shape and 28%
choose a thinner ideal shape
In ranked studies, the overweight was below the
child in a wheelchair or with facial disfigurement
Girls are less accepting of overweight same sex
peers than are boys
Anorexia Nervosa
3rd most common chronic illness
in girls 15-19 yrs
Prevalence of 0.5%
Increasing number of young patients 8-14 yrs
Average duration of 4 years
Long term mortality of 20-25%
Suicide rate ~ 5%
50% relapse rate in 1 year
Bulimia
Patients can be underweight, normal weight or
overweight
Often keep binge eating + purging secret
Pre-occupied with weight, appearance, body
image
Misuse insulin or thyroid medication
Laxative of abuse more common
Occurs on a continuum from a few
times/month to several times a day
Definition of
Anorexia Nervosa
Criteria :
a. Refusal to maintain bodyweight at or above a
minimally normal weight for age and height
b. Intense fear of gaining weight or becoming fat
c. Undue influence of body weight on selfevaluation denial of seriousness of current low
body weight
d. Amenorrhea absence of consecutive
menstrual cycles
Types : Restricting, Binge eating
Definition of
Bulimia Nervosa
Criteria :
a. Eating in discrete period of time (e.g. within any 2-hr
period) and amount of food that is definitely larger than
most people would eat OR a sense of lack of control
over eating during the episode (feeling one cant stop
eating)
b. To prevent weight gain : self induced vomiting, misuse
of laxative, diuretics, enemas, fasting
c. binge eating or vomiting/laxatives etc at least twice a
week for three months
d. Self evaluation unduly influenced by body shape
Differential Diagnosis
IDDM
Thyrotoxicosis
Malignancy
Mal-absorption
HIV
depression
At Risk
Female adolescent
Young children
Children with mother who have eating
disorders
Athletes dancers, gymnastics
Older women
Patients with a history of sexual abuse
Victims of rape
Male Anorexia
One in ten patients with an eating
disorders is male
Increasing incidence of eating disorders in
male homosexuals
High incidence of substance abuse
Part of impulse control problem where
alcohol, drugs and food are misused
Increasing in sports such as wrestling,
body building, jockeys
Emaciation
Bradycardia
Hypotension
Pallor
Acrocyanosis
Ankle edema
Breast atrophy
Growth stunting ( pre-pubertal )
Etiology
Genetic monozygotic twins, 55% concordance
dizygotic twins, 7% concordance
But may be mediated by :
- growth rate in childhood
- Predisposition to obesity
- Personality type
- Predisposition to psychiatric illness
Etiology
1694 Morton : destruction of tone of nerves
Early 1900s : pituitary dysfunction
Mid 1980s : peptides i.e. CCK, NPY, substance
P
1990s :
1. imbalance in serotonin mechanisms
2. common end-point of stress, depression
and anxiety
Serotonin
Serotonin (5HT) is responsible for
suppression of food intake
Serotonin acts to induce satiety
Serotonin regulates body weight via
thermo genesis and nutrient selection
Serotonin function is different in men &
women BUT may be a secondary
condition related to starvation
SEVERITY TEATMENT
CARE PROVIDER
Key Points
The aims of treatment of anorexia nervosa
is to establish healthy eating habits and
normal weight through the consumption of
regular meals and snacks building up to
2000 kcal/day, and to address factors to
result in relapse