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What is Colon Cancer?

Colon Cancer also known as Colorectal Cancer or Large Bowel Cancer


includes cancerous growths in the colon, rectum and appendix. Screening
for Colon cancer should begin at the age of 40 in healthy adults. 70 to 80
percent of colorectal cancer cases occur in adults without specific risk
factors. Colon cancer may affect any racial or ethnic group; however, some
studies suggest that Americans of northern European heritage have a
higher-than-average risk of colon cancer.

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What are Types of Colon Cancer?

Adenocarcinomas: These are the most common type of Colon Cancer and
originate in glands. They account for about 90-95 percent of all colorectal
Cancers and have two subtypes, Mucinous and signet ring cell. The Mucinous
subtype comprises about 10-15 percent of Adenocarcinomas while the signet ring
cell subtype comprises less than 0.1 percent of Adenocarcinomas.

Leiomyosarcomas: This type of Colon Cancer occurs in the smooth muscle of


the Colon. Leiomyosarcomas account for less than two percent of colorectal
Cancers and have a fairly high chance of metastasizing.

Lymphomas: These are the rare and are more likely to start in the rectum than in
the Colon. However, lymphomas that start somewhere else in the body are more
likely to spread to the Colon than to the rectum.

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Melanomas: This type of Colon cancer is rare. Usually, it results from a


melanoma that started somewhere else and then spread to the Colon or rectum.
Melanomas account for less than 2% of colorectal Cancers.

Neuroendocrine Tumors: This tumor is divided into two main categories:


aggressive and indolent.

Colorectal cancer, also called colon cancer or large bowel cancer, includes
cancerous growths in the colon, rectum and appendix. Colorectal cancers arise
from adenomatous polyps in the colon. These mushroom-shaped growths are
usually benign, but some develop into cancer over time. Localized colon cancer
is usually diagnosed through colonoscopy.

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Symptoms of Colon Cancer


Leaking of bowel contents into the pelvis can cause inflammation and infection.
Change in frequency or character of stool.
Small-caliber or ribbon-like stools.
Sensation of incomplete evacuation after a bowel movement.
Rectal bleeding may be hidden and chronic and may show up as an iron deficiency
anemia.

Causes of Colon Cancer


A family history of colorectal cancer and polyps.
The presence of polyps in the large intestine.
Chronic ulcerative colitis.

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How is for Colon Cancer diagnosed?

Colonoscopy: An endoscope is inserted into the rectum and advanced through the
colon, through this the doctor can examine the entire colon.

Diagnosis is confirmed with a colon biopsy - Stage of disease is confirmed by


pathologists and imaging tests, such as computerized tomography (CT or CAT) scans.

Endoscopic ultrasound and magnetic resonance imaging (MRI) may also be used to
stage rectal cancer.

Sigmoidoscopy: In this an endoscope is interested in the rectum and moved through


the left side of the colon. It cannot be used to view the middle and right sides of the
colon.

Fecal occult blood test (FOBT) along with Complete blood count (CBC to check for
anemia and CT, MRI or PET scans of the abdomen, pelvic area.

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Stages of Colon Cancer

The staging of colon cancer helps doctors determine a course of treatment. Staging is
done on a scale from 0 to 4, with the higher stages indicating a cancer than has spread
more throughout the body.
Stage 0: In this stage, the cancer hasnt grown beyond the inner layer of the colon or
rectum.
Stage I: The cancer has spread through the colons inner lining, but hasnt spread
beyond the colon wall or rectum.
Stage II: The cancer has grown through the colon or rectal wall, but hasnt spread to
nearby lymph nodes.
Stage III: The cancer has invaded nearby lymph nodes but isnt affecting other parts of
the body.
Stage IV: The cancer has metastasized throughout the body to sites such as the liver,
lung, ovaries or the lining of the abdominal cavity.

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Colon Cancer Treatment and Surgery in India
Surgery
Surgery is the mainstay of treatment and involves in block removal of diseased segment with
adequate margins, surrounding tissue and lymph nodes. The names given to such resections are
right hemicolectomy, transverse colectomy, left hemicolectomy, sigmoid colectomy, and subtotal
colectomy.
Polypectomy: If the cancer is found in a polyp (a small piece of bulging tissue), the polyp is often
removed during a colonoscopy.
Local excision: If the cancer is found on the inside surface of the rectum and has not spread into
the wall of the rectum, the cancer and a small amount of surrounding healthy tissue is removed .
Resection: If the cancer has spread into the wall of the rectum, the section of the rectum with
cancer and nearby healthy tissue is removed. Sometimes the tissue between the rectum and the
abdominal wall is also removed. The lymph nodes near the rectum are removed and checked under
a microscope for signs of cancer.
Pelvic exenteration: If the cancer has spread to other organs near the rectum, the lower colon,
rectum, and bladder are removed. In women, the cervix, vagina, ovaries, and nearby lymph nodes
may be removed. In men, the prostate may be removed. Artificial openings (stoma) are made for
urine and stool to flow from the body to a collection bag .
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Radiation therapy
Radiation therapy is a cancer treatment that uses high-energy beams or other types
of radiation to kill cancer cells. There are two types of radiation therapy. External
radiation therapy uses linear accelerators outside the body to send radiation
toward the cancer. Internal radiation therapy (Brachytherapy) uses a radioactive
substance sealed in needles, seeds, wires, or catheters that are placed directly into
or near the cancer. The way the radiation therapy is given depends on the type and
stage of the cancer being treated.

Chemotherapy
Chemotherapy is a cancer treatment that uses drugs to stop the growth of cancer
cells, either by killing the cells or by stopping the cells from dividing. When
chemotherapy is taken by mouth or injected into a vein or muscle, the drugs enter
the bloodstream and can reach cancer cells throughout the body (systemic
chemotherapy). When chemotherapy is placed directly in the cerebrospinal fluid,
an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer
cells in those areas (regional chemotherapy). The way the chemotherapy is given
depends on the type and stage of the cancer being treated.

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Other Types of Treatment

Targeted therapy
Targeted therapy is a type of treatment that uses drugs or other substances to
identify and attack specific cancer cells without harming normal cells.
Monoclonal antibody therapy is a type of targeted therapy being studied in the
treatment of rectal cancer.
Monoclonal antibody therapy uses antibodies made in the laboratory from a
single type of immune system cell. These antibodies can identify substances
on cancer cells or normal substances that may help cancer cells grow. The
antibodies attach to the substances and kill the cancer cells, block their
growth, or keep them from spreading. Monoclonal antibodies are given by
infusion. They may be used alone or to carry drugs, toxins, or radioactive
material directly to cancer cells.

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Most Advanced Minimally Invasive or Laparoscopic Colon


Cancer Surgery in India

Advantages of Minimally Invasive Laparoscopic Colon Cancer


Surgery

Less surgical trauma, shorter hospitalization, Improved cosmetic


results.
Reduced post operative pain, faster recovery and return to daily
activities and
normal diet.
Less postoperative pain killer requirement.

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FAQ - Colon Cancer Treatment in India

How will doctor know if I have Colon Cancer?


The doctor may perform a number of procedures, including one or more of the following
to confirm the cancer.
Why should I have a colonoscopy?
Colonoscopy is used to prevent colorectal cancer from developing. The test can find
inflamed tissue, ulcers, and polyps which may lead to colorectal cancer. Screening tests
find cancer early.
Which is the Best Hospital in India for treatment of Colon Cancer?
India has not one but many better than the best hospitals for cancer treatment. Mail us
your medical report and we will find the hospital most suitable to treat your medical
condition.
Is it safe to get Colon Cancer Treatment and Surgery in India?
The medical fraternity in India is famed for excellence, and leads in Cancer surgeries.
Thousands of cancer operations are performed in India each year with maximum success
rate, making the safety obvious.
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