Documente Academic
Documente Profesional
Documente Cultură
Subjects HUMANS
Conditon HEALTHY PATHOLOGY
Type of -psycho- -pain -psycho- -pain
measure physics behaviors physics behaviors
magnitude estimation
tolerance
VAS
0
X 10
no pain worst pain
imaginable
Ethics?
Critiques?
? OUCH!!!
? Heart rate; blood pressure
? Pupil dilation, sweating
? Moaning
? Grimaces
? Postures
0
X 10
no pain worst pain
imaginable
BUT: consider
Ethics?
Critiques?
Grunau RV, Craig KD. Pain expression in neonates: facial action and cry. Pain. 1987;28:395-410.
HEAL LANCE
ENDOMETRIOSIS IN WOMEN
Netter FN.
Reproductive
System, Ciba,
West Caulfield
NJ, 1965.
ENDOMETRIOSIS IN RATS
Autotransplants of pieces of uterine horn in the abdomen
(For sham surgery, piece of fat are autotransplanted.)
ENDOMETRIOSIS shamENDOMETRIOSIS
100 100
Escape Response (%) Pre Pre
Post 80 Post
80
60 60
PROESTRUS 40 *
**
40
20
* 20
**
0 0
0.01 0.1 0.25 0.35 0.5 0.65 0.8 0.95 0.01 0.1 0.2 0.35 0.45 0.6 0.75 0.85
100 100
Escape Response (%)
80 80
60 60
ESTRUS 40 40
20 20
0 0
0.01 0.1 0.25 0.35 0.5 0.65 0.8 0.95 0.01 0.1 0.2 0.35 0.45 0.6 0.75 0.85
100 100
Escape Response (%)
80 80
60 60
METESTRUS 40 40
20 20
0 0
0.01 0.1 0.25 0.35 0.5 0.65 0.8 0.95 0.01 0.1 0.2 0.35 0.45 0.6 0.75 0.85
100 100
Escape Response (%)
80 80
DIESTRUS 60 60
40 40
20 20
0 0
0.01 0.1 0.25 0.35 0.5 0.65 0.8 0.95 0.01 0.1 0.2 0.35 0.45 0.6 0.75 0.85
Distention Volume (ml) Distention Volume (ml)
Hard to study.
How do you know if your dog or a newborn is in pain?
Most work so far has been done in animals the context of a
known pathophysiological condition.
Little has been done in neonates or other non-verbal humans.
[Example: Terstegen C, Koot HM, de Boer JB, Tibboel D. Measuring pain in children with cognitive impairment: pain
response to surgical procedures. Pain. 2003 May;103(1-2):187-98.]
Class demonstration:
BAT DETECTOR
Pain Seminar, Class # 2, MEASURES, p. 14
Situation #6, #8: HEALTH/PATHOLOGY
ANIMALS --pain behaviors--
..but shamENDO
surgery decreases
them!!
SILENT STONES