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LYMPHOMA CANCER

Lymphoma Cancer Treatment India Lymphoma is a cancer that originates


in lymph nodes and appears as an enlargement of the node (a tumor).
Lymphoid leukemias, which also originate in lymphocytes typically
involve only circulating blood and the bone marrow ,where blood cells are
generated in a process termed haematopoesis. Lymphomas are a part of a
broad group of diseases called hematological neoplasms.

The lymphatic system is part of the bodys immune defence system. Its job
is to help fight diseases and infection. Lymphatic vessels carry lymph, a
colorless watery fluid that contains infection-fighting cells called
lymphocytes. Along this network of vessels are groups of small, bean-
shaped organs called lymph nodes. Clusters of lymphnodes are found in
the underarms, groin, neck, chest, and abdomen

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What are the common symptoms of Lymphoma?
There are a number of common signs and symptoms that are associated with Lymphoma
however it must be pointed out that these symptoms can also be caused by numerous, less
severe conditions and so anyone suffering with any of the following symptoms should not
self-diagnose Lymphoma.
The common symptoms include : -
Swollen lymph glands - although these often develop in the neck, armpit and groin areas they can
also develop in the chest and these lymph glands can not be felt externally. This means that they
can be swollen for some time without causing any external swelling that can be felt with the
fingers.
Fever and night sweats - because Cancerous cells are present in the body the immune system
launches an attack and this causes the body's internal temperature to rise, which is felt as a fever.
Unexplained weight loss - Lymphoma can affect any system within the body and occasionally it
affects the digestive system which then fails to function at its best. This means that food is not
absorbed properly and the body begins to lose weight.
Tiredness and fatigue - again this can occur when the digestive system is affected and the
impaired food absorption leaves the body with little energy. It also occurs because the body is
constantly trying to fight the spread and development of Cancerous cells.
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What are the types of Lymphoma?
There are two types of lymphoma: Hodgkin lymphoma (HL, also called Hodgkin's
disease) and non-Hodgkin lymphoma (NHL). Both HL and NHL can occur in the same
places and have similar symptoms. Their differences are visible at a microscopic
level. Hodgkin lymphoma develops from a specific abnormal lineage of B cells. There are
five subtypes of HL. NHL may derive from either abnormal B or T cells, and its 30
subtypes are distinguished by unique genetic markers.

Hodgkin Lymphoma (HL) -


Hodgkin lymphoma can arise anywhere in the body where lymphocytes are found. HL
has characteristics that differentiate it from all of the other types of lymphoma, most
notably the presence of a cell called the Reed-Sternberg cell. A Reed-Sternberg cell is a
large, abnormal cell that does not protect the body from infection. When it abnormally
multiplies, it often forms a tumor within a lymph node and attracts inflammatory cells
around it. While the cause is unknown, certain factors have been shown to increase the
risk of developing Hodgkin lymphoma. Treatment for Hodgkin lymphoma may include
chemotherapy and/or radiation therapy. In certain cases, bone marrow or stem cell
transplant may be recommended, especially if the disease does not respond to initial
treatment or if it returns despite an initial response to treatment.
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Non - Hodgkin Lymphomas (NHL)


Non - Hodgkin's lymphoma is a general term for a large group
of lymphatic cancers that comprise approximately 90% of all diagnosed
lymphomas. Hodgkin's disease contain specific cells called Reed-Sternberg
cells that are not found in patients with non-Hodgkin's lymphoma.
Approximately 85% of all non-Hodgkin's lymphomas originate in B-
lymphocytes and are sometimes referred to as B-cell lymphomas. Non-
Hodgkin lymphoma begins when a lymphocyte (usually a B cell) becomes
abnormal. The abnormal cell divides to make copies of itself. The new cells
divide again and again, making more and more abnormal cells. The abnormal
cells don't die when they should. They don't protect the body from infections or
other diseases. The buildup of extra cells often forms a mass of tissue called a
growth or tumor. In general, the risk factors for non-Hodgkin lymphoma
include the following: Weakened immune system Certain infections like Human
immunodeficiency virus, Epstein-Barr virus (EBV), Helicobacter pylori,
Human T-cell leukemia/lymphoma virus type 1 (HTLV-1) and Hepatitis C.

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Diagnosis of Lymphoma

blood tests, including complete blood count (CBC).


blood chemistry, including tests of liver and kidney function.
bone marrow biopsy or aspiration.
lumbar puncture (spinal tap) to check for Cancer spread to the central nervous system
(brain and spinal cord).
ultrasound.
computed tomography (CT) of the chest and abdomen or sometimes X-rays.
magnetic resonance imaging (MRI).
bone scan or gallium scan (when a radioactive material is injected into the bloodstream
to look for evidence of inflammation or bone tumors).
gallium scan to look for tumor or inflammatory cells.
Positron emission tomography (PET) scan to look for abnormal cells.

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Treatment of Lymphoma at World Top Hospitals in India

There are several factors that you will need to take into account when deciding on
your treatment. They include patients age, stage of lymphoma, likely progression
of lymphoma, sub-type of lymphoma and possible side effects of the treatments.

Chemotherapy
Chemotherapy is a widely used treatment for lymphoma, often combined with
radiotherapy. The type of chemotherapy you receive will depend on the type and
stage of your lymphoma. If it is thought that your lymphoma is curable you will
normally receive an aggressive treatment regime designed to kill all of the
cancerous cells in your body. However, if a cure is unlikely, then a more moderate
treatment regime may be used which can often provide long-term relief from
symptoms. An aggressive chemotherapy regime will involve you receiving
injections of chemotherapy (intravenous chemotherapy) while a more moderate
regime will involve you taking chemotherapy tablets (oral chemotherapy).

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Radiotherapy

Radiotherapy is often used to treat stage 1 and 2 lymphomas, when the


cancerous cells are located in only one part of the body. Treatment is normally
given daily, over the space of 2-6 weeks. The radiographer will need to first
carefully plan your treatment. This may involve one or several appointments,
where the radiographer uses a machine to 'map' out the lymphoma and decide
what parts of your body the radiotherapy should be directed at. This may
involve making small marks on your skin with a kind of marker pen.
Radiotherapy itself is painless, but it does have a number of common side
effects. These can vary, depending on which part of your body is being
treated. For example, if the affected lymph nodes are in your throat
radiotherapy can lead to a sore throat, while treatment to the head can lead to
hair loss.

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Monoclonal Antibody Therapy


Monoclonal antibodies are drugs that can recognize and find specific cells in the
body. These drugs can be designed to find a particular type of cancer cell in the body.
The monoclonal antibodies attach themselves to the cancer cells and destroy them.
There are different types of monoclonal antibody treatment. They can be used alone,
with radiotherapy or with chemotherapy. A monoclonal antibody treatment is available
for certain types of lymphoma. The treatment may be used as part of initial treatment
or if the disease recurs. In lymphoma, monoclonal antibody treatment can be given in
different ways.

Transplants
Sometimes high doses of chemotherapy destroy the lymphoma cells and your bone
marrow. To help your bone marrow make new healthy blood cells, some stem cells
may be taken with a special machine before chemotherapy is given. These cells are
then transplanted into the body. These transplanted cells will then find their way to the
bone marrow and restore it, so that it can build healthy new blood cells.

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FAQ Lymphoma Cancer Treatment in India


Is Lymphoma inherited?
No. There is little to no evidence that these diseases are inherited. There are genetic components
to the diseases and often there are alterations in the DNA but the cause of these changes is
unknown and occurs later in life.
Is it safe to get Lymphoma Treatment in India?
The medical fraternity in India is famed for excellence, and leads in Cancer surgeries. Thousands
of cancer operations are performed in India each year with maximum success rate, making the
safety obvious.
How to find the Best Lymphoma Treatment and Surgery in India?
As there are many top class surgeons in India, finding the best can be tricky. Send us your
medical report and we will choose from among the best surgeons most suitable for your
condition.
What are the Benefits of getting Lymphoma Treatment in India?
Cancer Hospitals in India are equipped with the most advanced medical treatment. They have the
most extensive neuro-diagnostic and imaging facilities including Asias most advanced MRI and
CT technology. Personalized care and attention is provided with value added services besides
results of world class standard at a very low cost affordable to all sections of society.
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