FAT N EC R O S IS

TIM PPDS MATA FK UNUD

Widya Mahayani
Adhi surya
AA Istri Ratih
Eka Naryati
 Focal area kerusakan lemak, biasa
terjadi setelah trauma pankreas ,
atau pankreatitis akut
dihasilkan pengeluaran secara
patologis enzim pankreas ke
parenkim sekitarnya & cavum
peritonial
A C U TE PA N C R EATITIS

Trauma parenkim pankreas yg

reversibel yg berkaitan dgn
inflamasi
Insiden setiap tahun di negara
barat: 10-20 kasus 100,000 org
Kelainan di traktus biliary dan
alcoholism : penyebab dari 80%
kasus
Etiologic Factors in A cute Pancreatitis

METABOLIC
Alcoholism
Hyperlipoproteinemia
Hypercalcemia
Drugs (e.g., azathioprine)
GENETIC
Mutations in the cationic trypsinogen (PRSS1) and trypsin inhibitor (SPINK1)
genes
MECHANICAL
Gallstones
Trauma
Iatrogenic injury
Operative injury
Endoscopic procedures with dye injection
VASCULAR
Shock
Atheroembolism
Vasculitis
INFECTIOUS
Mumps
M EKAN ISM E
ClinicalFeatures

Abdominal pain the pain is

constant and intense and is
often referred to the upper back
and occasionally can be
associated with referred pain to
the left shoulder
Laboratory findings include
marked elevation of serum
amylase levels during the first
24 hours, followed within 72 to
Terima Kasih