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Is charcterised by
spontaneous bleeding
extensive bleeding after minimal trauma
Platelets Disorder
Clinical features
petechiae
ecchymoses
mucose membranes bleeding
menorrhagia
rare internal, intracranial bleeding
Diagnosis
platelet count <100G/l
bleeding time - usually normal
peripheral blood smear - large platelets
bone marrow examination - normal or increased number of
megakariocytes
antibodies against Gp IIb/IIIa
shortened platelet survival
Treatment of ITP