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fever
Emma Ximena Crdova Guerrero
Nancy Isabel Guerra Nieva
Scarlet fever (Scarlet fever)
*Contagious bacterial infection.
- Chills
- Headaches
- Nausea
- Vomiting
Streptococcus pyogenes
Gram-positive
cocci
Peptidoglycan
, lipoteichoic
acid, M and F
protein in its
cell wall.
They contain
the antigen
from group A.
It produces
large areas of
-hemolysis.
Transmission from:
Asymptomatic
carriers
Convalescent
people
By direct contact
Virulence factors
They are determined by:
Frequently they
Pathogenesis
Portal of entry: Oropharynx by airborne
droplets.
Penetrate through damage skins or mucous
membranes
Presented three lines of pathogenesis: toxic,
septic and allergic
Could not attach to host tissues and this is
would removed by salivary and mucous
fluid and by this mechanism and exfoliation
of the epithelium.
Specific adhesion allows competition
between normal flora and GABH.
The adhesion involves group A
streptococcal adhesins.
Adherence: This confers tissue specificity .
This induce localized cytokine production
and inflammatory responses
- The M protein attachment
to keratinocytes in skin
infections Keratinocytes.
- In the skin bind to the C
repeat region of M protein
When the C1 and C2 repeats were deleted, the M
protein was decreased in its ability to bind keratinocyte
Membrane cofactor protein (CD46) has been
demonstrated to be a receptor on keratinocytes for the
streptococcal M protein.
The hyaluronic acid capsule is required for resistance
to phagocytosis
Diagnosis
Bacterioscopic study
- Clindamycin
- Azithromycin
- Clarithromycin
- The following measures are
recommended:
Repose
Thermal control
Complete and balanced diet
Evading drying household
powders
- It is widely distributed in
most body fluids and bones
- It is absorbed 60% orally,
its binding to proteins is
high and 56% is
metabolized in the liver.
Complications
In most cases, the rash and other symptoms of
scarlet fever will be gone in about two weeks.
However, when its left untreated, scarlet fever can
Rheumatic
cause serious fever
complications. These can include:
Kidney disease
Ear infections
Skin infections
Throat abscesses
Pneumonia
BIBLIOGRAPHY
http://www.austincc.edu/microbio/2993v/sp.pdf
https://www2c.cdc.gov/podcasts/media/pdf/Scarl
et%20Fever.pdf
http://emedicine.medscape.com/article/1053253-
overview
http://phpa.dhmh.maryland.gov/IDEHASharedDocu
ments/scarlet_fever.pdf