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(Down Syndrome)
BY: CHRISTABELLE INTONG
A Brief History
Down Syndrome is a genetic disorder that is caused
by abnormal cell division which results when there
is extra genetic material from chromosome 21. It is
the most common genetic chromosomal disorder.
Down Syndrome was named after a physician, John
Langdon Down. He was the first person to identify it
in 1866. In 1959, a French pediatrician, Jerome
Lejeune found out that those who have Down
syndrome have an extra chromosome.
The term that was first used for Down syndrome
was Mongolism because the features of the
children look like the people from Mongolia. The
Asians complained that the name was offensive.
Later on Americans changed it to Down Syndrome.
People today in the United Kingdom still call it
Downs
John Langdon Down
How?
Chromosomes
are made up of DNA and protein.
Human cells normally have 46 chromosomes and can be arranged in 23 pairs. Pairs 22 and
During conception a baby receives genetic data (DNA) from the parents and comes in the
form of 46 chromosomes. The baby inherits 23 chromosomes from each of the father and
the mother.
Human Cells divide into two different ways: Mitosis and Meiosis.
Mitosis is when one cell becomes two cells and have the same type/number as the parent
cell.
Meiosis is when one cell splits into two and contains half of the amount of chromosomes as
Down Syndrome is not fatal but it can link to many health problems.
Down Syndrome can lead to other problems:
Hearing loss
Ear infections
Eye diseases
Heart Defects
Leukemia
Infectious
Facts/ Statistics