What is Heterochromia Heterochromia is a condition that is mostly acquired from birth where the irises are different colors. Heterochromia normally comes in three different types. Most cases of heterochromia are mild and have little to no affect on health. This is caused by hyperpigmentation or hypopigmentation in the eyes. Eye color is determined mostly by the amount of melanin. This is also determined by chromosomes. The Three Types The most notable type of heterochromia is complete heterochromia. This is where one eye’s color is different without any other colors mixed in, than the other. Partial Heterochromia is when part of one eye is a different color than the rest of it. Central Heterochromia is when the inner ring of the iris is different color than the outer area of the iris. Heterochromia in infants Heterochromia acquired at birth is approximately 6 out 1000 but, most of the time it is hardly noticeable and unassociated with any other abnormality. It is usually caused by genetics and is associated with as congenital syndrome. Many causes that tend to follow heterochromia are Horner’s Syndrome, Sturge-Weber Syndrome, Piebaldism, and Bourneville disease. An infant with Heterochromia should be examined by an ophthalmologist and a pediatrician to check for other disorders or problems. Acquired means of Heterochromia The inflammation of the iritis or anterior uveitis of any cause, can be from tuberculosis and sarcoidosis. Pigment dispersion syndrome, which is a loss of pigment from the posterior surface of the iris. The pigment gets dispersed throughout the interior of the eye and deposited on different intraocular structures. This includes the anterior of the of the surface iris causing it to darken. This also cause pigmentary glaucoma. Trauma, either blunt force or penetrating may cause unilateral lightening of the iris. Ocular Melanosis, which is when increased pigmentation around the eye and surrounding tissue. Possible Treatment
If it is secondary to another underlying condition, then treatment will
be directed at that condition. In certain situations when major cosmetic impairment are present a tinted contact lens can be used to darken the lighter appearing eye or vice versa. Sometimes two contacts are given to find an average color for each eye. The overall prognosis is that there are little to no visual complaints. Most cases are extremely mild and unassociated with other eye diseases. Citations
Turbert, David. “Heterochromia.” American Academy of
Ophthalmology, American Academy of Optamology, 5 Jan. 2018, www.aao.org/eye-health/diseases/what-is-heterochromia. Dahl, Andrew A. “Heterochromia Iridis Causes, Types & Rarity.” MedicineNet, 27 Nov. 2017, www.medicinenet.com/heterochromia_iridis/article.htm. Penning, Christa. “Citelighter Is the Fast, Fun, and Easy Way to Do Research.” Citelighter, www.citelighter.com/science/health/knowledgecards/heterochro mia-iridum.