Liposome Production

Liposomes are considered as the most common and

well-investigated drug carriers with significant clinical
implications for the delivery of anti-tumor,
antimicrobial, and anti-inflammatory drugs. Having
advanced preparation technologies for various
liposomes, Creative Biostructure established
multifunctional liposome platforms to support all types
of research in drug development.
Liposomal drug delivery systems have been shown
beneficial for stabilizing therapeutic compounds,
improving biodistribution at target sites, prolonging
circulation time, and minimizing systemic toxicity. Their
flexible properties and functions can be manipulated to
address different delivery considerations by modifying
liposome formulations. Our liposome production
platforms tailor the design and preparation of various
liposomes to meet delivery demands across different
applications:
Non-PEGylated Liposome (NPL) Production

Using phospholipids from natural and synthetic sources, we manufacture high

quality NPL immunoliposomes. Our NPL technology provides an alternative
carrier with lower toxicity allowing for a higher accumulative dose.

Multivesicular Liposome Production

Multivesicular liposomes encapsulate drugs with greater efficiency, ensure a

better controlled and prolonged drug release. We can also customize
multivesicular liposomes to support the further study requires frequent multiple
administrations.
Lysolipid Thermally Sensitive Liposomes
Thermally sensitive liposomes deliver drugs to the targeted region and release
them when local hyperthermia is applied. Therefore, it is a promising tool for
site-specific chemotherapy. We offer production services for thermally sensitive
liposomes to facilitate precise treatment both in intravascular and extravascular
regions.

Photo-Activated Liposome Production

Targeted drug release by photo-activated liposomes is induced by exposure to
light with a specific wavelength. The technology is suitable for sustained and on
demand drug delivery capability. We can manufacture various kinds of photo-
activated liposomes, such as light-induced oxidation liposomes and
photocleavable liposomes.
Transferosome Production
Compared to other liposomes, transferosomes are mainly used in transdermal
drug delivery system due to its higher lipid bilayer flexibility and permeability,
which facilitate liposomes to deform and pass through narrow constriction to
underlying viable skins. Our expertise supports transferosome production for
non-invasive therapeutic uses.

Ethosome Production
Ethosomes is one of the approaches for increasing skin penetrating by high
ethanol contents which facilitate drug encapsulated ethosomes to permeate
easily inside the deep skin layers. We produce ethosomes to meet applications
in pharmaceuticals, veterinary, and cosmetic fields.
Pharmacosome Production
Pharmacosomes are amphiphilic phospholipids complexes of drugs bearing
active hydrogens and bound to phospholipids via hydrogen bonds. They are
suitable for delivery of poorly soluble drugs with minimized degradation and
increased bioavailability. We provide pharmacosome production to enhance the
solubility for both hydrophilic and lipophilic drugs.

Cyclodextrin-based Liposome Production

Cyclodextrin-based liposomes can deliver volatile and hydrophobic drugs with
better therapeutic effects. We provide this double-loading technique to provide
an access to explore their applications in pharmaceutical, cosmetic and food
industry.
Nano-Liposomes Formulation Production
Nanoliposomes refer to nanoscale lipid vesicles which possesses the same
physical, structural, thermodynamic properties as normal liposomes. We
manufacture nano-sized liposomes with advanced biocompatibility and
biodegradability to support potential applications in nanotherapy, food industry,
cosmetics, and agriculture.

Asymmetric Liposome Production

In contrast to conventional symmetric liposomes mentioned above, asymmetric
liposomes mimic the natural membranes characterized with different lipid
composition in inner and outer leaflets. This good bio-similarity enhances the
use of asymmetric liposomes as drug carriers, especially for anti-tumor therapy.
Unilamellar vesicular liposomes with incorporated lipophilic drugs.
Features of our services
•Liposome preparation: Using our incomparable liposome technologies,
we produce customized liposomes with specific properties in demand.
•Efficiency analysis: Based on our professional knowledge in liposome
analysis and characterization, we can offer precise assays for liposomes.
Parameter characterizations include visual appearance, size distribution,
stability, Zeta potential, lamellarity, entrapment efficiency, and release
rate.
Creative Biostructure is your reliable partner in studying of novel drug
delivery systems. We will support you with superb expertise, advanced
equipment, and satisfactory customer service.
Thank you !
Excerpt from:
https://www.creative-biostructure.com/Liposome-
Production-546.htm