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Define GFR
Define creatinine clearance test
Discuss intrinsic and extrinsic markers for assessing GFR
Describe the indications, preparation and procedure,
precaution and interpretation of creatinine clearance test
Describe the procedure of 24 Hour urine sample collection
Write down the formula for assessing creatinine clearance
GFR
• The rate of blood flow filtered by the kidney's glomerulus into
Bowman's capsule per unit of time is the glomerular filtration rate, or
GFR.
11/26/2018
Serum creatinine conc. inversely related
to GFR
16 Serum Creatinine
Relationship between
Concentration and Creatinine Clearance
800
Serum Creatinine (µmol/L)
700
600
500
400
300
200
100
0
0 25 50 75 100 125
Creatinine Clearance (ml/min)