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1. DNA is transcribed into RNA through the process of transcription.
2. Transcription initiation requires transcription factors and RNA polymerase to access DNA and begin RNA synthesis.
3. Newly synthesized RNA transcripts then undergo processing where introns are removed and 5' caps and 3' poly-A tails are added. Mature mRNA is then exported from the nucleus through nuclear pores.
1. DNA is transcribed into RNA through the process of transcription.
2. Transcription initiation requires transcription factors and RNA polymerase to access DNA and begin RNA synthesis.
3. Newly synthesized RNA transcripts then undergo processing where introns are removed and 5' caps and 3' poly-A tails are added. Mature mRNA is then exported from the nucleus through nuclear pores.
1. DNA is transcribed into RNA through the process of transcription.
2. Transcription initiation requires transcription factors and RNA polymerase to access DNA and begin RNA synthesis.
3. Newly synthesized RNA transcripts then undergo processing where introns are removed and 5' caps and 3' poly-A tails are added. Mature mRNA is then exported from the nucleus through nuclear pores.
DNA Replication Initiation DNA Elongation Transcription Processing Degradation Export RNA Translation Initiation Degradation Elongation Protein Processing Targeting Chapter 6 • Transcription • Sections • From DNA to RNA – The start of the chapter to the end of “Mature eucaryotic mRNAs are selectively exported from the nucleus” RNA structure
RNA is single stranded polymer of C, G, A, U
Can have secondary structure but typically not a
double helix (Fig. 6-6) RNA structure
many types of RNA made:
•mRNA: encodes proteins,
•snRNA: RNA processing
•snoRNA: rRNA processing
•tRNA: translation
•rRNA: translation Transcription initiation
DNA acts as a template for RNA synthesis (Fig 6-
9) Transcription initiation
DNA acts as a template for RNA synthesis
Synthesis by RNA polymerase -RNA Pol
RNA Pol I makes tRNA and rRNA
RNA Poly II makes mRNA in nucleus
Control of transcription
Transcription initiation by RNA Pol II requires
general transcription factors (Fig 6-16) Control of transcription (Fig. 6-16)