METABOLISME SEL

1. KATABOLISME (Penguraian)
2. ANABOLISME (Penyusunan)
 KATABOLISME

• RESPIRASI AEROB (OKSIDASI)

• RESPIRASI ANAEROB (FERMENTASI)

RESPIRASI AEROB (OKSIDASI)
4 TAHAP RESPIRASI AEROB

• GLIKOLISIS
• DO (DEKARBOKSILASI OKSIDATIF)
• SIKLUS KREBS
• TRANSPOR ELEKTRON
GLIKOLISIS Glukosa (C6)
Heksokinase
Glukosa 6 phospat
Phosphoglukoisomerase
Fruktosa 6 phospat
Phosphofruktokinase
Fruktosa 1,6 Diphospat
Aldolase / Isomerase
2 mol PGAL
Triosephosphatdehidrogenase
2 mol 1,3 bipospogliserat
Phosphogliserokinase
2 mol 3 pospogliserat
Phosphogliseromutase
2 mol 2 pospogliserat
Enolase
2 mol pospoenolpiruvat
Piruvatkinase
2 mol asam piruvat (C3)
G
L
I
K
O
L
I
S
I
S
Dekarboksilasi Oksidatif
Dekarboksilasi Oksidatif masuk ke Siklus Krebs
S
I
K
L
U
S

K
R
E
B
S
T
R
A
N
S
P
O
R

E
L
E
K
T
R
O
N
Hasil Akhir Respirasi Aerob
 2 e– + 2 H+
2 e– + H+
NAD+ NADH

H Dehydrogenase
O O
H H
Reduction of NAD+
C NH2 + 2[H] C NH2 +
(from food)
Oxidation of NADH
N+ N
Nicotinamide Nicotinamide
CH2 (oxidized form) (reduced form)
O O
O P O–

O H H

O P O– HO OH
NH2
HO
CH2
O N
N
H
N H
N
O

H H

HO OH Figure 9.4
 Oksidasi Protein, Karbohidrat dan Lemak
Proteins Carbohydrates Fats

Amino Sugars Glycerol Fatty

acids acids

Glycolysis
Glucose

Glyceraldehyde-3- P

NH3 Pyruvate

Acetyl CoA

Citric
acid
cycle

Oxidative
Figure 9.19 phosphorylation
 Fermentasi Alkohol dan Asam Laktat
2 ADP + 2 P1 2 ATP O–
C O
C O
Glucose Glycolysis
CH3
2 Pyruvate

2 NAD+ 2 NADH 2 CO2

H H
H C OH C O
CH3 CH3
2 Ethanol 2 Acetaldehyde
(a) Alcohol fermentation

2 ADP + 2 P1 2 ATP

Glucose Glycolysis O–
C O
C O
2 NAD+ 2 NADH
O CH3
C O
H C OH
CH3
2 Lactate
Figure 9.17
(b) Lactic acid fermentation
 Glucose

CYTOSOL

Pyruvate

No O2 present O2 present
Fermentation Cellular respiration

MITOCHONDRION

Ethanol Acetyl CoA

or
lactate
Citric
acid
cycle

Figure 9.18
 Anabolisme

1. Fotosintesis
(Reaksi Terang dan Reaksi Gelap)
2. Kemosintesis
Kloroplas
Contoh Kemosintesis