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인제대힉교 부산백병원
산부인과학 교실
R1 서 영진
The maternal organism responds passively to
signals emanating from embronic-fetal and
extraembryonic tissues
The conceptus is the dynamic force in the
pregnancy
Essential for successful pregnancy
-implantation, maternal recognition of
pregnancy, immunological acceptance,
endocrine function, nutrition, parturition
Determination of gestational age(1)
Embryo
(the 3rd weeks after fertilization)
-most pregnant test: hCG (+)
-embryonic disc: well defined
-chorionic sac: 1 cm
·The end of the 4th week
-embryo: 4~5 mm
-chorionic sac: 2~3 cm
-primitive heart (the middle oh the 4th week)
-arm & leg buds
-amnion is beginning
Morphological growth(3)
Fetus
(occur 8th weeks after fertilization)
-the embryo-fetus: nearly 4 cm
-the major portion of lung
Length of fetus
-crown-rump height: the variability in the length of
the legs and the difficulty of maintaining them in
extension
Molding
-the bones of the cranium are normally connected
only by a thin layer of fibrous tissue which allows
considerable shifting or sliding of each bone to
accommodate the size and shape of the maternal
pelvis
Fetal brain
-myelination of the ventral roots of the cerebrospinal
nerves and brain stem: begins at 6 months
Mechanism of transfer
-molecular weight is clearly important in determining
the rate of transfer by diffusion
-the smaller, the more rapid
Proteins
-Ig G: Fc receptor on trophoblast, cross the placenta
same concentration in cord & maternal area
-Ig M: increase-fetal infection (immune system)
Nutrition of the fetus(6)
Ions and trace metals
-iodide transport across the placenta
carrier mediated, energy-requiring avtive process