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Aging process is really a disease

1. The genetic Mt-DNA vs the c-DNA


• 2. The target organ :
• a. nutrition given cell ( 22.p.72 and
• 22.p.92 genes) vs the endothelial
• response
• b. fibroprotein & collagen vs GAG
• c. Auto-immune Ag formation.
• d. Metabolic syndrome&Organ dysfunction
• 3. Ecosystem’s influenced variables ( oxydant,
• foetal & inheritance program, nutrition,
• life style / corpus amygdale )

• PROBLEM OF AGING PROCESS

• 1. DEFICIT POWER FOR SUPPORTING ENDOTHERMIC


• BIOCHEMISTRY OF LIFE
• 2. DECREASING OF GENERAL ENDOTHERMIC
• BIOCHEMISTRY
• 3 REGRESSION PROCESS OF LIFE LEADING TO
• GENERAL DEGENERATION AND ATROPHY
• 4. EACH SYSTEM HAS ITS EACH OWN TYPE OF
• REGRESSION
Exothermic biochemistry BIO.MOLE-
CULAR OF
1. oxidant
Mt-DNA 2. Energy THE CELL
150.000

Endothermic
biochemistry C-DNA
No repairy
Mt-DNA

Decreasing energy
nucleus
1. Aging process 17.p.23
2. Mets
3. Auto-immune disease
4. Functional disbalancing
5. Dissynchronizing condition
6. Apoptosis
Cavert by the capsule
(AFTER FUSION WITHIN
r-RNA TO BE h-RNA)
(AFTER FUSION WITHIN
R-RNA TO BE h-RNA)
Producen of energy

Side effect of producing oxidant

Mt-DNA 1.Oxydized NADH + Reduced obequinon


3.Redox Obequionon + C cytochrome

Redox C cytochrome (Q ten enzyme)

4.Q ten + 0-2 ATP ase ( AMP to


be ATP )
2.Succinat Obequinon

DNA Endonuclease material for promoting :


DNA polymerase 1. Specific amino acid
DNA ligase Arginin, asparatic acid, cystein, alanin
glutamic acid, glycine, histidin, proline,
serine,l-thyrosine
Preventing the
2. large amount glycine
16 destroyers+ anti-
oxidants
Destroyer variables of the Mt-DNA
4.
(alkaline and negative charge) which has no protector and
repair mechanism
1. Too much to be used 9. Sulfonyl-ureas
2. Antibiotics 10.immunosupressant
3. Phospholipase enzyme 11. Antilipidaemia
4. DNA endonuclease enz . 12. Antiviral drug
5. Glycinolysis enzyme 13. Antitumorca, calmodulin.
6. ATP ase enzyme cytosolid ca
14. Anaesthesia
7. Ischemics 15. K porus opn
8. Ionizing Radiation 16. Toxin
EMBRYONAL STEM CELL
STADIUM MORULA,
BLASTULA, GAS 1. OMNIPOTENT
TRULA
STEM – CELL /
TOTIPOTENT
STEM-CELL STEM - CELL
MEMAKAI
FACTS
2. PLURIPOTENT
STEM-CELL
ADULT STEM-CELL
1:10.000 MEDULLA OSSEUM ALA 0SSIS
PUBIS, STERNUM, UMBILICUS,
1:100.000 ORGANON, BLOOD

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