A SEMINAR

ON
Nanotechnology in
medicine BY
UNDER THE GUIDANCE OF, B.SHARATH CHANDRA
Mrs. KABITA BANIK 16171R0061
BPHARM-IVth Year

Department of Pharmacy
BHARAT INSTITUTE OF TECHNOLOGY
Ibrahimpatnam (M),R.R District,TS-501510
Nanotechnology in
medicine
CONTENTS
•INTRODUCTION
•TECHNIQUES
•NANO-TECHNOLOGY
INTRODUCTION
• Simply they are Extremly small particles.
• A particle of any shape with a dimension ranging form 1nm to 100nm
can be identify as nano-particles.
• According to the international union of pure and applied chemistry
(IUPAC).
• A particle of any shape with the dimension in the range of 1nm to
100nm can be identified as nano-particle.
So Why Are Nano-Particles
Important ?
Mechanical
Optical properties Electrical properties
properties

Magnetic properties Catalytic properties

SIZE & SHAPE MATTER AT
NANO-SCALE
• Different size & shape of nano-particles of the same material its show
different physical & chemical properties.
• Due to these different properties nano-particles are used in almost all
fields of science.
• Usage of nano-particles increased drastically during last few decades.
TECHNIQUES
Hot Homogenization Technique:
• In this method the drug along with
liquid lipid is dispersed under steady
stirring by a high shear device in the
aqueous surfactant solution of same
temperature.
• The pre-emulsion obtained is
homogenized by utilizing a piston gap
homogeniser and the hot
nanoemulsion is chilled off to
roomtemperature where the lipid
recrystallises and prompts to
formation of nanoparticles
Cold Homogenization Technique:
• Cold homogenization is done with the
solid lipid containing drug.
• The initial step of both the cold and
hot homogenization techniques is the
same.
• IN final step melt containing drug is
cooled quickly with ice (or) liquid
nitrogen for circulation of lipid matrix
as appered in figure.
• Cold homogenization technique
minimises the thermal exposure of
the sample.
NANO-TECHNOLOGY
• Nano-technology allows Reserchers to build new
tools that are actually smaller than cells.
• Based on computer chip technology diagnostic
devices such as nano-assays are thousands.
• Ingestible Capsules are containing sensors,
cameras and alredy changing the face of
medicine.
APPLICATION OF NANO-TECHNOLOGY IN
MEDICAL FIELD
Drug Delivery

Surgery

Medical Robotics

Therapeutic Applications

Cell Repair
 NANOTECHNOLOGY IN IMPLANTS
• Two types of implants : Passive and active
• Passive implants include bone, dental, knee-joint
• Active implants include cochlear, retinal and neural implants as well
as pacemakers.
 SMART PILLS
(Improve drug adherence and patient outcomes)

PILL CAM VIBRANT DOSE TRACKING PILLS ATMO GAS CAPSULE MIT’s SMART
CAPSULE SENSOR CAPSULE
PILLS CAM
• In 2001 the ingestible camera became the first (FDA)
Approved smart pills.
• By 2008 pill cams had been used in more than 2
Million procedures.
VIBRANT CAPSULE
• Vibrant capsule promote muscle contraction to
jumpstart digestion.
• Effectively treats constipation without laxatives (or)
any major side effects.
DOSE TRACKING PILLS
• Each pill contains a senor which relays data through a patch worn by
the patient.
• App tracks drug dosage and time log can be shared with doctors and
others.
• Treatment non adherence cost up to $290B in the U.S alone.
ATOM GAS CAPSULE
• A permeable membrane allows gases to enter the capsule.
• Sensor detect leves of oxygen, hydrogen, and co2.
• Oxygen levels allow researchers to pinpoint the capsule’s location.
• Hydrogen and co2 offer scientists valuable data about the gut’s
microbiome.
MIT’s SMART SENSOR CAPSULES
• Capsules unfold into a Y- Shaped lodging in the stomach for about a
month.
• Sensor track vital signs for diagnosis and treatment monitoring.
• Bluetooth connection limited to an arm’s length for better security.
• Preloaded compartments can be customized to release medications.
NANO BOTS
• This are used for magnetic micro surgery like,
• Preforming Eye Surgeries.
• Clearing Blocked Arteries.
• Collecting Biopsies.
 Advantages
• Efficient Drug Delivery
• Repairing Body Cells Becomes Easy
• Replacing Abnormal Genes
CONCLUSION
Challenges
• Cost and Manufacturing.
• Consumer perceptions.

Islamic input
• Seek the knowledge.
• Don’t do damage on earth.
• Human can’t be immortal
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THANK YOU.