TANIN

Created by :
Anindia Jembar Fauzani
Inesya Yesita Cendana
 TANIN

Tannins are polyphenolic secondary metabolites of higher plants, They comprise oligomeric and polymeric
proanthocyanidins and can possess different interflavanyl coupling and substitution patterns (condensed
tannins) or (gallotannins, ellagitannins and complex tannins)

The hydrolysable tannins are gallotannins and elagitannins (Figure 14.1-6). They are polyesters of glucose and
can be hydrolysed by acids or enzymes such as tannase. They release sugar upon hydrolysis. Gallotannins are
the simplest hydrolysable tannins, containing a polyphenolic and a polyol residue (mostly derived from D-glucos

Gallotannins are the simplest hydrolysable tannins, containing a

polyphenolic and a polyol residue (mostly derived from D-glucose)

Tannic acid is a polymer of about eight monomers of gallic acid and

glucose.

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 Ellagitanins

Ellagitannins are formed from the gallotannins by the

oxidative coupling of at least two galloyl units, yielding an
axially chiral hexahydroxydiphenoyl (HHDP) unit.
Ellagitannins are unstable and hydrolysed over time with
formation of free ellagic acid and decrease of their
solubility.
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 Clasification of tanin

Condensed Tanins
Condensed tannins are not very stable;
they can be oxidized into soluble
phlobaphens, which have no tanning The hydrolysis type Tanin
properties anymore Condensed and
The hydrolysable-type tannins (they contain
hydrolysable tannins can be
gallic and ellagic acids) produce blue color
distinguished with ferric chloride reaction
with ferric-(III)-chloride and the condensed-
butthis reaction is not specific, every
type tannins (catechins) green (greenish-
compound containing phenolic OH-
blue), respectively. This reaction is
groups gives this reaction. The structure
accomplished in neutral or mildly acidic
of the complex can be seen in The color
medium. The Fe3+-ions can produce chelate
of the complex depends on the number
complexes with phenolic, electron donor
and the position of the phenolic OH- The Power of PowerPoint | thepopp.com 4
OH-groups located in ortho positions.

Were Traditionally
Tannins were traditionally used for
“tanning”, converting animal hides
to leather. This refers to one of their
leading properties, the ability to
interact with proteins and precipitate
them. Tannin-containing drugs have
been used traditionally as styptics
Function Of Tanin
Internally
Internally they can be used for
the protection of inflamed
surfaces of mouth and throat.
They have antidiarroeal effect,
and they have been applied as
antidotes in heavy metal and
alkaloid poisoning.
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The internal absorption of
concomitantly administerd
medicines may be delayed by tannin
containing-drugs. For this reason,
the product should be taken 1 hour
or more before or after intake of
other medicinal products
5
 Tanin Use

patients susceptible to allergic reactions

should use tannin-containing drugs
carefully or not use them at all.
1 2 during pregnancy and lactation not
set

children under the age of 18 has

not been established,
3 4 its use is contraindicated in inflammatory
bowel disease and constipation tooLong-term
use of tannin-containing drugs may be
hepatotoxic.

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 Ratanhiae radix

Uses
PLANT
Krameria triandra Ruiz et Pavon (syn: Krameria It is traditionally used asadstringent, against stomatis,
lappacea Burdet et Simpson) – Peruvian bleeding of the gums, gingivitis (inflammation of the

rhatany(Krameriaceae) gums), and pharyngitis (especially as a tincture).

However, the scientific documentation of these effects is
The plant is native to the mountain slopes of Peru and
Drug
Bolivia.
sparse.
Dosage
The tincture produced from Rhatany root contains Adult and elderly daily dose: If rhatany root is used internally,
not less than 1% m/m of tannins, expressed as the single dose is 0.5-1.5 g, and the maximum daily dose is
1.5-4.5 g, but it should be used internally only for a short
pyrogallol.
period of time. For external use, a 2% extract should be
prepared with 5 minutes of boiling.
Constituen
Grand layer
It contains 5-15% of catechin tannins,
phlobaphenes („rhatania-red”) and neolignans. Sed eius inimicus an, ei duis tincidunt
consetetur mea. Movet maluisset sadipscing.

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 Plants Contains Tanin

Rhatanie Rhadix Tanaman Empedu

01 04

Empedu Kulit pohon ek

02 05

Daun Hamamelis Cuercus Cortex

03 06

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Derivatives of gallic acid and
ellagic acid.
Derivatives of
catechin.

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 Arcturus
Free PowerPoint Template

Jun Akizaki
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Introduction
 Before Starting

An mea mundi soleat, ne falli tacimates eum. Summo discere adversarium per te, ad
usu nullam prompta blandit, id cum quot facilis vulputate.

Nam mutat mazim legere ut, cu summo essent recteque vis, eu impetus viderer
platonem est. Eos verear antiopam intellegat ex.

Omnium malorum adversarium eam ad, usu in tollit singulis conceptam, eam agam
constituam temporibus ea.

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 Presentation Topic

At vero quidam civibus cum, vim

ex vidisse tibique dissentias

An mea mundi soleat, ne falli tacimates eum. Summo discere adversarium per te, ad usu nullam prompta blandit, id
cum quot facilis vulputate. Nam mutat mazim legere ut, cu summo essent recteque vis, eu impetus viderer platonem
est. Eos verear antiopam intellegat ex.

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 THANKS
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QUESTION