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ESSENTIALS OF
Anatomy &
Physiology
Tenth Edition
Cinnamon Vanputte
Jennifer Regan
Andrew Russo
© 2019 McGraw-Hill Education. All rights reserved. Authorized only for instructor use in the classroom. No reproduction or further distribution permitted without the prior written consent of McGraw-Hill Education.
2
Chapter 2
Basic Chemistry
Matter: anything that occupies space and has
mass (solid, liquid, or gas)
Mass: amount of matter in an object
Weight: gravitational force acting on object
Figure 2.2
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Subatomic Particles
Proton: positive charged particle located inside
the nucleus
Neutron: neutral charged particle located inside
the nucleus
Electron: negative charged particle located
outside the nucleus
Model of an Atom
Figure 2.1
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Chemical Bonds
Chemical bonds occur when outermost
electrons (valence shell electrons) are
transferred or shared between atoms
Types of chemical bonds
• Ionic
• Covalent
• Hydrogen
Ionic Bonding
Figure 2.3
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Covalent Bonding 1
Covalent Bonding 2
Figure 2.4
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Hydrogen Bonding 1
Figure 2.5
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Hydrogen Bonding 2
Hydrogen Bonds
Figure 2.6
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Chemical Reactions
Chemical reactions occur when there is a
formation or breaking of chemical bonds between
atoms, ions, molecules, or compounds.
Reactants: substances that enter into the reaction
Products: substances that result from the reaction
A+B C+D
Reactants Product
Figure 2.8
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Exchange reaction:
• combination of synthesis and decomposition
reactions
• Example: AB + CD AC + BD
• Example: HCl + NaOH NaCl + H2O
Energy
Energy is the capacity to do work.
Work is the moving of matter.
Kinetic energy is energy in motion
Potential energy is stored energy
Chemical Energy
Chemical energy is a form of potential energy
stored in chemical bonds
Food molecules such as glucose contain
potential energy
An example of a reaction that releases energy is
the breakdown of ATP (adenosine triphosphate)
to ADP (adenosine diphosphate) and a
phosphate group
ATP ADP + P
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pH Scale
Figure 2.9
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Inorganic Chemistry versus Organic
Chemistry
Inorganic chemistry deals with those substances
that do not contain carbon
Organic chemistry is the study of carbon-
containing substances
Exception: some carbon containing compounds
are not organic in that they do not also contain
hydrogen, such as CO2 (carbon dioxide)
Organic Molecules
Carbon’s ability to form covalent bonds with
other atoms makes it possible the formation of
large, diverse, complicated molecules for life.
The four major groups of organic molecules
essential to living organisms are carbohydrates,
lipids, proteins, and nucleic acids.
Carbohydrates 1
Characteristics of Carbohydrates
• Contain C, H, O
• H:O is a 2:1 ratio
• Example: C6H12O6
Carbohydrates 2
Disaccharide:
• 2 sugars
• Example: glucose + fructose = sucrose
• Example: glucose + galactose = lactose
Polysaccharide:
• many sugars
• Example: starch, grain, vegetables, glycogen
Carbohydrates 3
Figure 2.11a
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Functions of Carbohydrates
Short-term energy storage
Converted to glucose quickly
Glucose is used to make ATP (energy)
Brain cells require glucose
Characteristics of Lipids
Contain C, H, O
Contain a lower proportion of oxygen to carbon
than do carbohydrates
Insoluble in water
Examples: fats, oils, cholesterol, triglycerides,
phospholipids
Functions of Lipids
Long term energy storage
Insulates against heat loss
Protective cushion for organs
Cholesterol is part of the cell membrane
structure
Types of Lipids
Saturated:
• single covalent bonds between carbon atoms
• Examples: beef, pork, whole milk, cheese, eggs
Unsaturated:
• one or more double covalent bonds between carbons
• Examples: olive oil, fish oil, sunflower oil
Triglycerides
Figure 2.12
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Fatty Acids
Figure 2.13
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Phospholipids
Figure 2.14
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Characteristics of Proteins
Contains C, H, O, N
Amino acids are the building blocks
20 different naturally occurring amino acids
Amino acids contain an amine (NH2) group and
carboxyl group
Amino acids are not stored, so a daily supply is
required
Figure 2.16
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Linear Sequence of Amino Acids in
a Protein
Figure 2.16c
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Protein Folding
Functions of Proteins
Used to make skin, hair, nails, muscles
Part of the hemoglobin molecule
Act as enzymes
Immune system functions
Muscle contractions (actin and myosin)
Part of the cell membrane
Protein Denaturation
Protein denaturation occurs when the hydrogen
bonds that maintain shape of a protein are
broken and the protein becomes nonfunctional.
Factors that can cause denaturation are: high
temperatures and/or improper pH
Enzymes
Enzymes are organic catalysts that increase the
rate at which biochemical reactions proceed
without the enzyme being permanently changed.
Enzymes work by lowering the energy of
activation.
Figure 2.17
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Enzyme Action
Figure 2.18
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Nucleic Acids
Composed of C, H, O, N, P
Examples: DNA (deoxyribonucleic acid) and RNA
(ribonucleic acid)
Nucleotides are the building blocks
Nucleotides are composed of a nitrogen base,
phosphate, and 5-carbon sugar
Structure of DNA
Figure 2.19
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Structure of ATP
Figure 2.20
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