EXERCISE

THE UNTOLD STORY

 • Individuals who exercised had 1· 49 (43·2%) fewer
days of poor mental health in the past month than
individuals who did not exercise but were otherwise
matched for several physical and sociodemographic
characteristics.

EXERCISE AND • The largest associations were seen for popular team
sports (22·3% lower), cycling (21·6% lower), and
MENTAL aerobic and gym activities (20·1% lower), as well as
HEALTH durations of 45 min and frequencies of three to five
times per week.
• https://www.thelancet.com/journals/lanpsy/article/PIIS2
215-0366(18)30227-X/fulltext
. August 08, 2018
LEGS POWER YOUR BRAIN

• The study involved restricting 4 month old male mice from

using their hind legs, but not their front legs, over a period of
28 days. 
• Limiting physical activity decreased the number of neural stem
cells by 70 percent compared to a control group of mice, which
were allowed to roam.
• Reducing exercise also seems to impact two genes, one of
which, CDK5Rap1, is very important for the health of
mitochondria
• The study was used to better help astronauts in space and
people suffering with Alzheimer's disease
Frontiers in Neuroscience 2018 (DOI: 10.3389/fnins.2018.00336)
GROWTH
CURVE AND
DOUBLING
TIME
NEURONS
HOW MICE LINKED TO HUMANS

• The research shows that using the legs, particularly

in weight-bearing exercise, sends signals to the brain
that are vital for the production of healthy neural
cells, essential for the brain and nervous system.
• Prospective studies indicate that physical inactivity is
one of the most frequent avoidable risk factors for
developing AD. Moreover, elevated physical activity
levels are associated with a lower risk of AD. The AD
patient who undertook exercise training showed
decreased neuropsychiatric symptoms, improvement
in cognitive function, and a slower decline in the
activities of daily life.
Frontiers in Neuroscience 2018 (DOI: 10.3389/fnins.2018.00336)
MICE STUDY
2.0
 LINKS TO
ALZHEIMER'S AGAIN
• We chose voluntary wheel running as it closely
mimics the choices humans have when exercising
because animals dictate the time, speed, and
distance of running throughout the experiment. Some
rats voluntarily run up to an astounding 20 km in one
night!
• The brain region showing the earliest and most
sustained neurotrophic upregulation in response to
exercise was the hippocampus. The hippocampus is a
brain region important in learning and memory and is
a target for early deterioration in neurodegenerative
diseases like Alzheimer’s disease.
BRAIN DERIVED
NEUROTROPHIC FACTOR
(BDNF)

• In situ hybridization measures
of BDNF messenger RNA
(mRNA) found a 20%
increased abundance
of BDNF mRNA from control
levels in the hippocampus
after 2–7 nights of running
Exercise and Sport Sciences Reviews: 
April 2002 - Volume 30 - Issue 2 - p 75-
79
 • This (microbial) community can weigh up to 2 kg
and are composed of roughly 100 trillion
microorganisms, including 1000 different species
of known bacteria with more than 3 million genes
• Mice with varying gut bacteria were made to
EXERCISE AND swim till failure. Study Results: SPF, 81.6, BF 67.2
YOUR GUT min, GF 39.0,

Exercise and Sport Sciences Reviews: 

January 2017 - Volume 45 - Issue 1 - p 41–47
 • yes: exercise does produce a more
diverse microbiota and does seem to reduce
pathogenic bacterial communities and
increase good communities. This represents
SO DOES a cycle whereby exercise manifests
EXERCISE a microbiota that enhances the colonization
of more health-promoting bacteria, reduces
IMPROVE THE the burden of pathogenic bacteria, and
GUT? improves exercise performance.

Exercise and Sport Sciences Reviews: 

January 2017 - Volume 45 - Issue 1 - p 41–47
 WHAT DOES THE
BIBLE HAVE TO SAY?
• 1 Corinthians 9:27

But I keep under my body, and bring

it into subjection: lest that by any
means, when I have preached to
others, I myself should be a
castaway.
• Proverbs 31:17

Who can find a virtuous

woman? … She girdeth her loins
with strength, and strengtheneth
her arms.
• 1 Timothy 4:8

For bodily exercise profiteth little:

but godliness is profitable unto all
things, having promise of the life
that now is, and of that which is to
come.
• 1 Corinthians 6:19

What? know ye not that your body is

the temple of the Holy Ghost which
is in you, which ye have of God, and
ye are not your own?
KEEP YOUR TEMPLE FIT!