Meningkatkan Imunitas

saat Wabah COVID-19

Gaga Irawan Nugraha
Fakultas Kedokteran, Universitas Padjadjaran
 Daya tahan
Tubuh

Usia
Nutrisi

Daya tahan
Tubuh

Usia
Nutrisi
1. Jenis
a) Makronutrient : Karbohidrat, lemak, protein
b) Mikronutrient: Vitamin dan mineral
2. Jadwal
3. Jumlah
 Skin

Mucous
First line membrane

Secretion of skin
and mucous
membrane
Non-Specific
Phagocytic white
blood cells Vitamin
A
Antomicrobial
Second line Protein
Defense
Mechanism
The inflammatory
response

Lymphocytes

Specific Third line

Antibodies

-Suplementasi vitamin A mengurangi morbiditas dan mortalitas karena campak, diare, dan
infeksi HIV pada anak
-Suplementasi vitamin A juga mengurangi morbiditas karena malaria dan Tuberculosis
 Skin

First line Mucous

membrane

Secretion of skin
and mucous
membrane
Non-Specific
Phagocytic white
blood cells β-Karoten

Second line Antomicrobial

Protein
Defense
Mechanism
The inflammatory
response

Lymphocytes

Specific Third line

Antibodies

-Suplementasi oral Fe tidak berhubungan dengan berkurangnya morbiditas dan insiden

infeksi termasuk malaria
 Skin

Mucous
First line membrane

Secretion of skin
and mucous
membrane
Non-Specific
Phagocytic white
blood cells Vitamin
C
Antomicrobial
Second line Protein
Defense
Mechanism
The inflammatory
response

Lymphocytes

Specific Third line

Antibodies
 Skin

Mucous
First line membrane

Secretion of skin
and mucous
membrane
Non-Specific
Phagocytic white
blood cells Vitamin E

Antomicrobial
Second line Protein
Defense
Mechanism
The inflammatory
response

Lymphocytes

Specific Third line

Antibodies
 Skin

Mucous
First line membrane

Secretion of skin
and mucous
membrane
Non-Specific
Phagocytic white
blood cells Zinc

Antomicrobial
Second line Protein
Defense
Mechanism
The inflammatory
response
Berperan pada
sintesis protein
Lymphocytes (replikasi DNA,
Specific Third line transkripsi RNA,
regulasi gen)
Antibodies

-Suplementasi Zn mengurangi durasi diare dan insiden diare dan pneumonia

-Menurunkan mortalitas pada Balita
 Skin

Mucous
First line membrane

Secretion of skin
and mucous
membrane
Non-Specific
Phagocytic white
blood cells Fe

Antomicrobial
Second line Protein
Defense
Mechanism
The inflammatory
response

Lymphocytes

Specific Third line

Antibodies
 Skin

Mucous
First line membrane

Secretion of skin
and mucous
membrane
Non-Specific
Phagocytic white
blood cells EPA dan
DHA
Antomicrobial
Second line Protein
Defense
Mechanism
The inflammatory
response

Lymphocytes

Specific Third line

Antibodies

-Pemberian EPA dan DHA >10% dari asupan lemak - immunosupresif

-Direkomendasikan pemberian yang lebih moderat; <10% meningkatkan fungsi imun
 Penyakit
penyerta

Nutrisi

Daya tahan
Tubuh

Usia
 Penyakit
penyerta

Aktivitas
Nutrisi
Fisik

Daya tahan
Tubuh

Usia
 Penyakit
penyerta

Aktivitas
Nutrisi
Fisik

Daya tahan
Tubuh

Usia Aktivitas
Fisik
 Penyakit
penyerta

Aktivitas
Nutrisi
Fisik

Daya tahan
Tubuh

Usia Merokok

Tidur /
Istirahat
Hatur
Nuhun...................