Sunteți pe pagina 1din 67

STEP 1:

Understand the problem:

5) (20) You have a wild type camel and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 White fur 636 Sharp teeth 280 White fur and yellow eyes 260 Wild type 66 White fur, yellow eyes and sharp teeth 74 Yellow eyes 26 White fur and sharp teeth 34 Total 2000 (6) Define the genes, their alleles and phenotypes.

STEP 1: This is a typical test cross problem where you will be expected to determine the linkage of the genes involved, distances between them, and whether interference exists.
5) (20) You have a wild type camel and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 White fur 636 Sharp teeth 280 White fur and yellow eyes 260 Wild type 66 White fur, yellow eyes and sharp teeth 74 Yellow eyes 26 White fur and sharp teeth 34 Total 2000 (6) Define the genes, their alleles and phenotypes.

STEP 1: First, define the alleles. There appears to be different genes, each with two alleles, so let's assign each a letter and write them below.
5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 White fur 636 Sharp teeth 280 White fur and yellow eyes 260 Wild type 66 White fur, yellow eyes and sharp teeth 74 Yellow eyes 26 White fur and sharp teeth 34 Total 2000 (6) Define the genes, their alleles and phenotypes.

STEP 1: First, define the alleles. There appears to be different genes, each with two alleles, so let's assign each a letter and write them below.
5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 White fur 636 Sharp teeth 280 White fur and yellow eyes 260 Wild type 66 White fur, yellow eyes and sharp teeth 74 Yellow eyes 26 White fur and sharp teeth 34 Total 2000 (6) Define the genes, their alleles and phenotypes.

W_ wild type fur Y _ wild type eyes T_ wild type teeth

ww white fur yy yellow eyes tt sharp teeth

STEP 1: First, define the alleles. There appears to be different genes, each with two alleles, so let's assign each a letter and write them below.
5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 White fur 636 Sharp teeth 280 White fur and yellow eyes 260 Wild type 66 White fur, yellow eyes and sharp teeth 74 Yellow eyes 26 White fur and sharp teeth 34 Total 2000 (6) Define the genes, their alleles and phenotypes.

W_ wild type fur Y _ wild type eyes T_ wild type teeth

ww white fur yy yellow eyes tt sharp teeth

STEP 1: First, define the alleles. There appears to be different genes, each with two alleles, so let's assign each a letter and write them below.
5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 White fur 636 Sharp teeth 280 White fur and yellow eyes 260 Wild type 66 White fur, yellow eyes and sharp teeth 74 Yellow eyes 26 White fur and sharp teeth 34 Total 2000 (6) Define the genes, their alleles and phenotypes.

CONGRATS! You just received SIX POINTS.


ww white fur yy yellow eyes tt sharp teeth

W_ wild type fur Y _ wild type eyes T_ wild type teeth

STEP 2: Now let's list the alleles involved in each of the gametes that made each variety of camel. For example, a wild type camel will be WYS, while a totally recessive camel will have the alleles wys.
5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 White fur 636 Sharp teeth 280 White fur and yellow eyes 260 Wild type 66 White fur, yellow eyes and sharp teeth 74 Yellow eyes 26 White fur and sharp teeth 34 Total 2000 (6) Define the genes, their alleles and phenotypes.

W_ wild type fur Y _ wild type eyes T_ wild type teeth

ww white fur yy yellow eyes tt sharp teeth

STEP 2: Now let's list the alleles involved in each of the gametes that made each variety of camel. For example, a wild type camel will be WYT, while a totally recessive camel will have the alleles wyt.
5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Sharp teeth 280 WYt White fur and yellow eyes 260 wyT Wild type 66 WYT White fur, yellow eyes and sharp teeth 74 wyt Yellow eyes 26 WyT White fur and sharp teeth 34 wYt Total 2000 (6) Define the genes, their alleles and phenotypes.

W_ wild type fur Y _ wild type eyes T_ wild type teeth

ww white fur yy yellow eyes tt sharp teeth

STEP 3: Now, we need to find the parentals and double recombinants. The parental varieties (two of them) will have largest number of individuals, while the two double recombinants will have the smallest number.
5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Sharp teeth 280 WYt White fur and yellow eyes 260 wyT Wild type 66 WYT White fur, yellow eyes and sharp teeth 74 wyt Yellow eyes 26 WyT White fur and sharp teeth 34 wYt Total 2000 (6) Define the genes, their alleles and phenotypes.

W_ wild type fur Y _ wild type eyes T_ wild type teeth

ww white fur yy yellow eyes tt sharp teeth

STEP 3: Now, we need to find the parentals and double recombinants. The parental varieties (two of them) will have largest number of individuals, while the two double recombinants will have the smallest number.
5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt parentals White fur 636 wYT Sharp teeth 280 WYt White fur and yellow eyes 260 wyT Wild type 66 WYT White fur, yellow eyes and sharp teeth 74 wyt Yellow eyes 26 WyT dbl. recomb. White fur and sharp teeth 34 wYt Total 2000 (6) Define the genes, their alleles and phenotypes.

W_ wild type fur Y _ wild type eyes T_ wild type teeth

ww white fur yy yellow eyes tt sharp teeth

STEP 4: Now it's time to find the gene order. The clearest way to find this is through trial and error. List the parental alleles in all possible orders as done below:
5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt parentals White fur 636 wYT Sharp teeth 280 WYt White fur and yellow eyes 260 wyT Wild type 66 WYT White fur, yellow eyes and sharp teeth 74 wyt Yellow eyes 26 WyT dbl. recomb. White fur and sharp teeth 34 wYt Total 2000 (6) Define the genes, their alleles and phenotypes.

W_ wild type fur Y _ wild type eyes T_ wild type teeth

ww white fur yy yellow eyes tt sharp teeth

STEP 4: Now it's time to find the gene order. The clearest way to find this is through trial and error. List the parental alleles in all three possible orders as done below:
5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt parentals White fur 636 wYT Sharp teeth 280 WYt White fur and yellow eyes 260 wyT Wild type 66 WYT White fur, yellow eyes and sharp teeth 74 wyt Yellow eyes 26 WyT dbl. recomb. White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

W y t w YT W t y w T y

TWy t wY

STEP 4: During a meiosis, a process known as crossing over will sometimes occur where two parental chromosomes cross and exchange portions of their chromosomes, generating recombinants. If this process happens twice, double recombinants result.
5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt parentals White fur 636 wYT Sharp teeth 280 WYs White fur and yellow eyes 260 wtS Wild type 66 WYS White fur, yellow eyes and sharp teeth 74 wys Yellow eyes 26 WtS dbl. recomb. White fur and sharp teeth 34 wYs Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

W y t w YT W t y w T y

TWy t wY

STEP 4: Since we have listed possible orders for the parental chromosomes, we can predict what the double recombinants would be for each by drawing zig-zag lines connecting each. Let's try the first one.

W y t w Y T

STEP 4: Since we have listed possible orders for the parental chromosomes, we can predict what the double recombinants would be for each order by drawing zig-zagging arrows. Let's try the first one.

W y t w Y T

WYt

STEP 4: Now, let's compare these double recombinants we generated to the actual double recombinants we found previously. If these allele combinations are the same, this is the correct order.

W y t w Y T

WYt

wyT

STEP 4: Now, let's compare these double recombinants we generated to the actual double recombinants we found previously. If these allele combinations are the same, this is the correct order.

W y t w Y T
Actual Double Recombinants: Yellow eyes White fur and sharp teeth 26 34

WYt

wyT

WyT wYt

STEP 4: Now, let's compare these double recombinants we generated to the actual double recombinants we found previously. If these allele combinations are the same, this is the correct order.

W y t w Y T
Actual Double Recombinants: Yellow eyes White fur and sharp teeth 26 34

WYt

wyT

WyT wYt

STEP 4:

This combination didn't work. Let's try another.

Actual Double Recombinants: Yellow eyes White fur and sharp teeth 26 34 WyT wYt

STEP 4:

This combination didn't work. Let's try another.

Possible Order #2

W t y w T Y
Actual Double Recombinants: Yellow eyes White fur and sharp teeth 26 34 WyT wYt

STEP 4:

This combination didn't work. Let's try another.

Possible Order #2

W t y w T Y
Actual Double Recombinants: Yellow eyes White fur and sharp teeth 26 34

WTy

wTY

WyT wYt

STEP 4:

Possible Order #2

W t y w T Y
Actual Double Recombinants: Yellow eyes White fur and sharp teeth 26 34

WTy

wTY

WyT wYt

STEP 4:

Notice how the combination of alleles is the same.

Possible Order #2

W t y w T Y
Actual Double Recombinants: Yellow eyes White fur and sharp teeth 26 34

WTy

wTY

WyT wYt

STEP 4:

Notice how the combination of alleles is the same.

Possible Order #2

W t y w T Y
Actual Double Recombinants: Yellow eyes White fur and sharp teeth 26 34

WTy

wTY

WyT wYt

STEP 4: map.

Now that we know the order of the genes on a chromosome, we can draw a

W t y

STEP 4: map.

Now that we know the order of the genes on a chromosome, we can draw a

W t y

STEP 4: Draw 3 lines through the oval (these will demonstrate your gene locations) and label them in order. It does not matter what version of the gene you use (capital or lowercase/wild type or recessive). The relative spacing doesn't really matter here either.

W t y

STEP 4: Draw 3 lines through the oval (these will demonstrate your gene locations) and label them in order. It does not matter what version of the gene you use (capital or lowercase/wild type or recessive). The relative spacing doesn't really matter here either.

W t y

STEP 4: Draw 3 lines through the oval (these will demonstrate your gene locations) and label them in order. It does not matter what version of the gene you use (capital or lowercase/wild type or recessive). The relative spacing doesn't really matter here either.

t y

STEP 4: Draw 3 lines through the oval (these will demonstrate your gene locations) and label them in order. It does not matter what version of the gene you use (capital or lowercase/wild type or recessive). The relative spacing doesn't really matter here either.

w t y

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T.

w t y

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T. - Write the parentals as done below (in the correct order):

W t y w T Y

w t y

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T. We will IGNORE Y for now. - Write the parentals as done below (in the correct order): - Determine the results of one crossing over event between W and T.

W t w T

w t y

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T. We will IGNORE Y for now. - Write the parentals as done below (in the correct order): - Determine the results of one crossing over event between W and T.

W t w T

WT

wt

w t y

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T. We will IGNORE Y for now. - Now look at the list showing the number of individuals with each allele combination:

W t w T

WT

wt

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Sharp teeth 280 WYt White fur and yellow eyes 260 wyT Wild type 66 WYT White fur, yellow eyes and sharp teeth 74 wyt Yellow eyes 26 WyT White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T. We will IGNORE Y for now. -Now look at the list showing the number of individuals with each allele combination: - Note every allele combination that possesses either a WT or a wt

W t w T

WT

wt

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Sharp teeth 280 WYt White fur and yellow eyes 260 wyT Wild type 66 WYT White fur, yellow eyes and sharp teeth 74 wyt Yellow eyes 26 WyT White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T. We will IGNORE Y for now. -Now look at the list showing the number of individuals with each allele combination: - Note every allele combination that possesses either a WT or a wt

W t w T

WT

wt

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Sharp teeth 280 WYt White fur and yellow eyes 260 wyT Wild type 66 WYT White fur, yellow eyes and sharp teeth 74 wyt Yellow eyes 26 WyT White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T. We will IGNORE Y for now. -Now look at the list showing the number of individuals with each allele combination: - Note every allele combination that possesses either a WT or a wt

W t w T

WT

wt

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Add these numbers Sharp teeth 280 WYt together and divide by White fur and yellow eyes 260 wyT the total number of Wild type 66 WYT individuals: White fur, yellow eyes and sharp teeth 74 wyt Yellow eyes 26 WyT White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T. We will IGNORE Y for now. -Now look at the list showing the number of individuals with each allele combination: - Note every allele combination that possesses either a WT or a wt

W t w T

WT

wt

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Add these numbers Sharp teeth 280 WYt together and divide by White fur and yellow eyes 260 wyT the total number of Wild type 66 WYT individuals: White fur, yellow eyes and sharp teeth 74 wyt 66 + 74 + 26 + 34 Yellow eyes 26 WyT 2000 White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T. We will IGNORE Y for now. -Now look at the list showing the number of individuals with each allele combination: - Note every allele combination that possesses either a WT or a wt

W t w T

WT

wt

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Add these numbers Sharp teeth 280 WYt together and divide by White fur and yellow eyes 260 wyT the total number of Wild type 66 WYT individuals: White fur, yellow eyes and sharp teeth 74 wyt 66 + 74 + 26 + 34 Yellow eyes 26 WyT 2000 White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T. We will IGNORE Y for now. -Now look at the list showing the number of individuals with each allele combination: - Note every allele combination that possesses either a WT or a wt

W t w T

WT

wt

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Add these numbers Sharp teeth 280 WYt together and divide by White fur and yellow eyes 260 wyT the total number of Wild type 66 WYT individuals: White fur, yellow eyes and sharp teeth 74 wyt 200 Yellow eyes 26 WyT 2000 White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T. We will IGNORE Y for now. -Now look at the list showing the number of individuals with each allele combination: - Note every allele combination that possesses either a WT or a wt

W t w T

WT

wt

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Add these numbers Sharp teeth 280 WYt together and divide by White fur and yellow eyes 260 wyT the total number of Wild type 66 WYT individuals: White fur, yellow eyes and sharp teeth 74 wyt 1 Yellow eyes 26 WyT 10 White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T. We will IGNORE Y for now. -Now look at the list showing the number of individuals with each allele combination: - Note every allele combination that possesses either a WT or a wt

W t w T

WT

wt

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Add these numbers Sharp teeth 280 WYt together and divide by White fur and yellow eyes 260 wyT the total number of Wild type 66 WYT individuals: White fur, yellow eyes and sharp teeth 74 wyt 10% or Yellow eyes 26 WyT 10centimorgans White fur and sharp teeth 34 wYt (10cM) Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

STEP 5: Now we need to determine the distances between each of the genes. Let's start with W and T. We will IGNORE Y for now. -Now look at the list showing the number of individuals with each allele combination: - Note every allele combination that possesses either a WT or a wt

W t w T

WT

wt

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT This is the distance Sharp teeth 280 WYt between W and T! White fur and yellow eyes 260 wyT Wild type 66 WYT White fur, yellow eyes and sharp teeth 74 wyt 10% or Yellow eyes 26 WyT 10centimorgans White fur and sharp teeth 34 wYt (10cM) Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

Label this distance on the map of our chromosome:

w t y

We find the distance between T and Y the same way!

w t y

We will IGNORE W for now since we will be finding the distance between T and Y. - Now look at the list showing the number of individuals with each allele combination:

yt Y T

Yt

yT

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Sharp teeth 280 WYt White fur and yellow eyes 260 wyT Wild type 66 WYT White fur, yellow eyes and sharp teeth 74 wyt Yellow eyes 26 WyT White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

We will IGNORE W for now since we will be finding the distance between T and Y. -Now look at the list showing the number of individuals with each allele combination: -Since the single recombinants will have Yt or yT, let's highlight those.

yt Y T

Yt

yT

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Sharp teeth 280 WYt White fur and yellow eyes 260 wyT Wild type 66 WYT White fur, yellow eyes and sharp teeth 74 wyt Yellow eyes 26 WyT White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

We will IGNORE W for now since we will be finding the distance between T and Y. -Now look at the list showing the number of individuals with each allele combination: -Since the single recombinants will have Yt or yT, let's highlight those.

yt Y T

Yt

yT

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Add these numbers Sharp teeth 280 WYt together and divide by White fur and yellow eyes 260 wyT the total number of Wild type 66 WYT individuals: White fur, yellow eyes and sharp teeth 74 wyt 280+260+26+34 Yellow eyes 26 WyT 2000 White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

We will IGNORE W for now since we will be finding the distance between T and Y. -Now look at the list showing the number of individuals with each allele combination: -Since the single recombinants will have Yt or yT, let's highlight those.

yt Y T

Yt

yT

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Add these numbers Sharp teeth 280 WYt together and divide by White fur and yellow eyes 260 wyT the total number of Wild type 66 WYT individuals: White fur, yellow eyes and sharp teeth 74 wyt 600 Yellow eyes 26 WyT 2000 White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

We will IGNORE W for now since we will be finding the distance between T and Y. -Now look at the list showing the number of individuals with each allele combination: -Since the single recombinants will have Yt or yT, let's highlight those.

yt Y T

Yt

yT

5) (20) You have a wild type camel (brown fur, black eyes, and normal teeth) and cross it to a camel that is homozygous for white fur, yellow eyes and sharp teeth. The progeny of that cross are as follows: Yellow eyes and sharp teeth 624 Wyt White fur 636 wYT Add these numbers Sharp teeth 280 WYt together and divide by White fur and yellow eyes 260 wyT the total number of Wild type 66 WYT individuals: White fur, yellow eyes and sharp teeth 74 wyt 30% or 30cM Yellow eyes 26 WyT White fur and sharp teeth 34 wYt Total 2000 (9) For the genes that are linked, draw a map with the distance between the genes.

Add the distance of T and Y (30cM) to the map as well and we've completed our map!

w t y

Add the distance of T and Y (30cM) to the map as well and we've completed our map!

w t y

Now let's check for interference:

w t y

Now let's check for interference: - Take the sum of the double recombinants

w t y

Now let's check for interference: - Take the sum of the double recombinants

Yellow eyes White fur and sharp teeth

26 +34 60

WyT wYt

w t y

Now let's check for interference: - Take the sum of the double recombinants - Divide by the total number of individuals

Yellow eyes White fur and sharp teeth

26 +34 60

WyT wYt

w t y

Now let's check for interference: - Take the sum of the double recombinants - Divide by the total number of individuals

Yellow eyes White fur and sharp teeth

26 +34 60

WyT wYt

60/2000 = 3/100

w t y

Now let's check for interference: - Take the sum of the double recombinants - Divide by the total number of individuals - Divide this number by the product of the distances (in decimal form)

Yellow eyes White fur and sharp teeth

26 +34 60

WyT wYt

60/2000 = 3/100

w t y

Now let's check for interference: - Take the sum of the double recombinants - Divide by the total number of individuals - Divide this number by the product of the distances (in decimal form)

Yellow eyes White fur and sharp teeth

26 +34 60

WyT wYt

60/2000 = 3/100 0.10 x 0.30

w t y

Now let's check for interference: - Take the sum of the double recombinants - Divide by the total number of individuals - Divide this number by the product of the distances (in decimal form)

Yellow eyes White fur and sharp teeth

26 +34 60

WyT wYt

60/2000 = 3/100 0.10 x 0.30

= 1

w t y

Now let's check for interference: - Take the sum of the double recombinants - Divide by the total number of individuals - Divide this number by the product of the distances (in decimal form)

Yellow eyes White fur and sharp teeth

26 +34 60

WyT wYt

60/2000 = 3/100 0.10 x 0.30

= 1

w t y

This number is our CoC (coefficient of coincidence)

Now let's check for interference: - Take the sum of the double recombinants - Divide by the total number of individuals - Divide this number by the product of the distances (in decimal form)

Yellow eyes White fur and sharp teeth

26 +34 60

WyT wYt

60/2000 = 3/100 0.10 x 0.30

= 1

w t y

This number is our CoC (coefficient of coincidence) The CoI (coefficient of interference) is defined as: 1 - CoC

Now let's check for interference: - Take the sum of the double recombinants - Divide by the total number of individuals - Divide this number by the product of the distances (in decimal form)

Yellow eyes White fur and sharp teeth

26 +34 60

WyT wYt

60/2000 = 3/100 0.10 x 0.30

= 1

w t y

This number is our CoC (coefficient of coincidence) The CoI (coefficient of interference) is defined as: 1 CoC So our CoI = 1 CoC

Now let's check for interference: - Take the sum of the double recombinants - Divide by the total number of individuals - Divide this number by the product of the distances (in decimal form)

Yellow eyes White fur and sharp teeth

26 +34 60

WyT wYt

60/2000 = 3/100 0.10 x 0.30

= 1

w t y

This number is our CoC (coefficient of coincidence) The CoI (coefficient of interference) is defined as: 1 CoC So our CoI = 1 CoC =11=0

Now let's check for interference: - Take the sum of the double recombinants - Divide by the total number of individuals - Divide this number by the product of the distances (in decimal form)

Yellow eyes White fur and sharp teeth

26 +34 60

WyT wYt

60/2000 = 3/100 0.10 x 0.30

= 1

w t y

This number is our CoC (coefficient of coincidence) The CoI (coefficient of interference) is defined as: 1 CoC So our CoI = 1 CoC =11=0 Since our CoI = 0, there is no interference! Two more points!

Tips and Hints for Gettin' an A in Genetics Complete ALL the practice tests Know every problem through and through if you don't understand a step in a practice problem, ask! This is a simple example; it is likely that the problems on your tests will have tricks in them, so be able to identify and respond to tricks Office hours and Genetics Problem Solvers are KEY Take clear lecture notes (copy everything Holmgren says on the board) Set aside a whole week to study for your tests Get plenty of sleep before the test, and bring food to keep up your energy during the exam The first test is probably the most difficult exam of the entire Bio210 sequencemeaning there is a great deal of room to do well Even if you're clueless, at least make an attempt. Partial credit is generous in this class! Show your work