Pirolul

..
N

CH3
N
O
HO

N
O

C - CH2 - CH2 - CH - C

OH

HO

NH2

C - CH2 - CH2 - CH2 - NH2

Pyracetamum
Piracetam
Nootropil

CH2 - C

O
NH2

Polyvinilpirolidonum
Polivinilpirolidona
Polividon,
Hemodez
N

- CH - CH2 -

Cyanocobalaminum
Cianocobalamin Vit. B 1 2
H

H
H3C

CH2OH

OH

H3C

O
O-P-O

CH3
O
CH3
C
CH2 - CH2 - C - NH2

H2N - C - H2C - H2C

B
H2N - C - H2C
N
H3C
O

N
Co

H3C
O

H2N - C - H2C - H2C

H2N - C - H2C

CH3CH3

CH - CH3

CH2

CH3
N

N
D

CH2 - CH2 - C - NH
CH3
O
CH2 - C - NH2
O

B
N

HN
D

corin
H
H
H

6 7

H3C

5 4

1
3

NH
2

5,6-dimetilbenzimidazol

OH

H3C

CH2OH
H

OH
O - P - OH

OH
CH - CH3
CH2
NH2

-D-ribofuranozilfosfat

D-1-aminopropanol-2
2

I.

Nucleotid:
H3C

CH2OH

OH

H3C

II.

OH
O - P - OH

Cobamid:

O
O
CH3
CH3
C
CH2 - CH2 - C - OH

HO - C - H2C - H2C
HN
B
C - H2C
N
H3C
O

N
Co

H3C
O

HO - C - H2C
O

CH3

HO - C - H2C - H2C

N
D

A
CH3CH3

CH2 - CH2 - C - OH
CH3
O
CH2 - C - NH2
O

N OH

NO

OH

Co

3
NaO3S

SO3Na

N O
O

NaO3S

2
Co + + 2 NH4SCN

SO3Na

NaO3S

nitrozo- -sare

SO3Na

3
Co +

coloratie rosie.

Co(SCN)2 + 2 NH4+

Coloratie albastru-verzui.

361

548

= 3,0 - 3,4 ;

361

278

= 1,7 - 1,88

Lincomycini hydrochloridum
Clorhidrat de lincomicin
8

C3H7

CH3

HO - CH

4
5

3
2

* C - NH - CH

. HCl
O H
HO
H
OH H
S - CH3
H
OH
H

CH3

. H2O

Cl orh i d rat d e 6,8- di d ehi d roxi - 6-[(2S ,4R)- 1-meti l - 4- p rop i lp i rol i d in -2- carb oxami d o]- 1me ti l ti o- D- eri tro- - D-gal acto- octap i ran ozi d mon oh i d rat

Clindamycini hydrochloridum
Clorhidrat de clindamicin
8

C3H7

4
5

CH3
HC - Cl

3
2

* C - NH - CH

. HCl . H2O
O H
H
OH H
S - CH3
H
OH
H

HO

CH3

Cl orh id rat d e 7-cl or 6,7,8-tri d eh i d roxi -N- [(2S ,4R)- 1-meti l - 4- p rop i lp i rol i d in -2carb oxami d o]- 1- me ti l ti o- ,L -treo- D-gal acto- octap i ran ozi d mon oh i d rat

Derivai ai prolinei
H3C
O
H

COOH
H

Captoprilum
H3C

R
COOH
H

H
CH2 - SH

C
N

Captopril

C
O

H
C

COOH
H

1-[(2S)-3-mercapto-2-metilpropionil]-L-prolin

Enalaprilum
Enalapril
H

H2C - H2C - C - N
O

CH3

H5C2O

COOH

COOH

COOH

Maleatul esterului etilic 1- [N-[(S)-1- carboxi -3-fenilpropil ]-L-alanil ]-L-prolin-1

CH3

H2C = C - COOH +

CH3 - C - S - H2C - CH - COOH

CH3 - C - SH

SOCl2

COOH

CH3

CH3

CH3 - C - S - H2C - CH - COCl

COOH

CH3 - C - S - H2C - CH - CO
CH3

NH3 CH3 - OH

COOH

N
HS - H2C - CH - CO
CH3

KIO3 + 5 KI + 3 H2SO4 3 I2 + 3 K2SO4 + 3 H2O

2 R-SH + I2 R-S-S-R + 2 HI
H2N

O
C - CH = CH - COOC2H5

CH3

C
C

O
COOCH2-C6H5

H
H

C - H2C - C - N
O

CH3

H5C2O

H2
Raney-Ni

CH3

C
C

H5C2O

COOCH2-C6H5

H2C - H2C - C - N

O
COOH

H2C - H2C - C - N
O

H5C2O

C
C
N

CH3

O
COOH
H

H2C - C - N
C
HO

C
C
N

CH3
O
COOH
H