Patologia esofagului i a Patologia esofagului i a

stomacului. stomacului.
STONAC, ESOFAC NORNA
Tabloul histologic normal al esofagului.
NUCOASA CASTR!C NORNAL (regiunea fundica)
Anomalii de dezvoltare a esofagului (atrezia esofagiana,
fistule esofagotraheale.)
Esofagita de reflux: tablou
macroscopic i endoscopic.
ESOFACUL BARRET
Pathogene Pathogeneza za
Adenocarcinom Adenocarcinomului esofagian ului esofagian
Barrett's esophagus Barrett's esophagus
(intestinal type) (intestinal type)
Barrett's with dysplasia Barrett's with dysplasia
(Carcinoma in (Carcinoma insitu) situ)
!nvasive adenocarcinoma !nvasive adenocarcinoma
ReIlux Esophagitis
CARC!NON ESOFAC!AN
CARC!NON ESOFAC!ANtablou microscopic.
aricele esofagiene
Autoimmune Gastritis
H. pylori Gastritis
CASTR!TA ACUT
CASTR!TA ACUT (!NF!LTRA]!A LEUCOC!TAR)
ormal ormal
Increased Attack Increased Attack
- - Hyperacidity Hyperacidity
Weak deIense Weak deIense
- - Helicobacter pylori Helicobacter pylori**
- - Stress, drugs, Stress, drugs, smoking smoking
!athogenesis
CASTR!TA
NENETR!ER
ULCER CASTR!C CRON!C
CER CASTR!C CRON!C
CER CASTR!C CRON!C N ACT!ZARE.
Cranulation tissue Cranulation tissue
]esutul de granula[ie
Zone of fibrous scarring Zone of fibrous scarring
ona cicatrizarii fibroase
POL!P H!PERPLAST!C CASTR!C
PO!P ADENONATOS CASTR!C
ADENOCARC!NON CASTR!C
ADENOCARC!NON CASTR!C
CARC!NON CASTR!C cu celule n inel de pecete.