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Introducere

1. 111= Dr. Haras Monica Andreia, 2012, Particularități ale osteoporozei la pacienții cu
tireotoxicoze, Teză de doctorat - rezumat

2. 5= Manuela Russu, 2007, Seria Ghiduri Clinice pentru Obstretică și Ginecologie.


Terapia menopauzei

3. 10= Corina Cristina Morcov, 2012, Influenţa compoziţiei corporale şi a greutăţii asupra
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1. 4= Prof. Dr. Eusebie Zbranca, 2008, Endocrinologie: ghid de diagnostic și tratament


în bolile endocrine, Ediția a III-a, p.207-225,382-389

Cap 1

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Hăulică Haulică I. Fiziologie umană, ediția a III-a. București, ed. Polirom,2007, 664-667.

Cap 2 toate sunt cu 200 in fata

Poza 210= G. Donald Whedon, Robert Proulx Heaney, ENCYCLOPEDIA BRITANNICA,


2012, Bone anatomy

Os 200= cautare poza

Poza 211 OpenStax College , Illustration from Anatomy & Physiology, Jun 19, 2013.

Poza 212

Poza 213= 3 cu wiliam

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1. 9 . Prof. Dr. Eusebie Zbranca, 2008, Endocrinologie: ghid de diagnostic și tratament


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Cap 3

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6. Cummings SR, Melton III LJ. Epidemiology and outcomes of osteoporotic fractures.
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7. WHO Study Group. Assessment of fracture risk and its application to postmenopausal
osteoporosis.World Health Organ Tech Ser 1984;8437.

8. Kanis JA. Diagnosis of osteoporosis and assessment of fracture risk. Lancet


2002;359:1929-36.

9. Close J, Ellis M, Hooper R, Glucksman E, Jackson S, Swift C. Prevention of falls in the


elderly trial (PROFET): a randomised controlled trial. Lancet 1999;353:93-7.

10. Hind K, Burrows M. Weight-bearing exercise and bone mineral accrual in children and
adolescents: a review of controlled trials. Bone, 2007;40(1):14- 27.

11. Compston J. How to manage osteoporosis after the menopause. Best Pract Res Clin
Rheumatol 2005; 19:1007-19.

12. Dennison E, Cole Z, Cooper C. Diagnosis and epidemiology of osteoporosis. Curr


Opinion Rheumatol 2005; 17:456-61
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Introducere ce am scos

Reid a studiat relaţia între ţesutul adipos şi os. Astfel autorul arată în lucrarea sa că
greutatea corporală are impact atât asupra turnover-ului osos cât şi asupra densităţii osoase,
fiind un important factor de risc pentru fracturile vertebrale şi de şold. Greutatea corporală
influenţează atât prin masa grasă cât şi prin masa slabă densitatea minerală osoasă. Masa
grasă acţionează prin mai multe mecanisme, odată prin presiunea scheletală ce o exercită, apoi
prin asocierea cu secreţia de hormoni activi pe os de către celulele beta pancreatice ca:
insulina, amilina, precum şi secreţia de către adipocite: a estrogenilor şi leptinei (Reid
2008).[10]
Actual este mai puţin clar modul în care diferite compartimente ale organismului
influenţează masa osoasă, uneori rezultatele diferitelor studii fiind conflictuale. Datele din
literatură demonstrează că masa slabă este un factor de predicţie mai bun pentru masa osoasă
decât masa grasă şi greutatea corporală totală, atât la femeile pre cât si postmenopauzale. Alţi
autori descriu masa slabă ca fiind mai predictivă la femei decât la bărbaţi (Jankowska şi colab.
2001).[10]