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Introducere ce am scos
Reid a studiat relaţia între ţesutul adipos şi os. Astfel autorul arată în lucrarea sa că
greutatea corporală are impact atât asupra turnover-ului osos cât şi asupra densităţii osoase,
fiind un important factor de risc pentru fracturile vertebrale şi de şold. Greutatea corporală
influenţează atât prin masa grasă cât şi prin masa slabă densitatea minerală osoasă. Masa
grasă acţionează prin mai multe mecanisme, odată prin presiunea scheletală ce o exercită, apoi
prin asocierea cu secreţia de hormoni activi pe os de către celulele beta pancreatice ca:
insulina, amilina, precum şi secreţia de către adipocite: a estrogenilor şi leptinei (Reid
2008).[10]
Actual este mai puţin clar modul în care diferite compartimente ale organismului
influenţează masa osoasă, uneori rezultatele diferitelor studii fiind conflictuale. Datele din
literatură demonstrează că masa slabă este un factor de predicţie mai bun pentru masa osoasă
decât masa grasă şi greutatea corporală totală, atât la femeile pre cât si postmenopauzale. Alţi
autori descriu masa slabă ca fiind mai predictivă la femei decât la bărbaţi (Jankowska şi colab.
2001).[10]