1.

Synthetically derived peptide that is used in a wide range of skincare and makeup
products.

Despite claims being made for acetyl hexapeptide-8 (argireline), there is a clinical study
revealing that this ingredient is not even remotely as effective as dermatological procedures in
reducing signs of aging.

Other studies on topical use of a moisturizer containing a 10% concentration of acetyl

hexapeptide-8 have shown it does not penetrate beyond the uppermost layers of skin, even
after several hours. That means it cannot affect factors in the underlying layers that lead to the
formation of expression lines.

On the other hand, research has shown this peptide can penetrate further into skin if specific
formulary steps are followed, including the type of emulsion (a higher water content showed
greater penetration). However, even then the peptide wasnt showing results equivalent to
cosmetic corrective procedures.

Still, like all peptides, acetyl hexapeptide-8 has water-binding properties and theoretical skin-
restoring ability. Its not a throwaway ingredient, but neither is it as miraculous as the
manufacturer would lead you to believe.

1. Peptid derivat sintetic care este utilizat ntr-o gam larg de produse de ngrijire a
pielii i produse de machiaj.

n ciuda preteniilor fcute pentru acetil hexapeptida-8 (argirelin), exist un studiu clinic care
arat c acest ingredient nu este la fel de eficient ca i procedurile dermatologice n reducerea
semnelor de mbtrnire.

Alte studii privind utilizarea local a unui hidratant care conine o concentraie de 10% acetil
hexapeptid-8 au artat c nu penetreaz dincolo de straturile superioare ale pielii, chiar dup
mai multe ore. Aceasta nseamn c nu poate afecta factorii din straturile care stau la baza
care duc la formarea liniilor de expresie.

Pe de alt parte, cercetrile au artat c aceast peptid poate ptrunde mai departe n piele
dac se respect paii specifici ai formulei, inclusiv tipul de emulsie (un coninut mai mare de
ap a artat o penetrare mai mare). Cu toate acestea, chiar i atunci, peptida nu a prezentat
rezultate echivalente cu procedurile corective cosmetice.

Totui, la fel ca toate peptidele, acetil hexapeptida-8 are proprieti de legare la ap i

capacitate teoretic de restaurare a pielii. Nu este un ingredient care arunc n aer, dar nici nu
este la fel de miraculos ca productorul s te fac s crezi.

References for this information:

Cutaneous and Ocular Toxicology, March 2015, pages 46-52
European Journal of Pharmaceutical Sciences, February 2015, pages 27-35
Dermatologic Therapy, September-October 2007, issue 5, pages 343-349
International Journal of Cosmetic Science, October 2002, issue 5, pages 303-310
 2. A neuropeptide sold under the commercial name of Argireline, is used as a muscle
relaxer. Also known as AHA-3.

Commonly referred to as Botox in a jar because its believed to inhibit the release of
neurotransmitters and relax the facial muscles- thus reducing expression lines and wrinkles.
Unfortunately, proof of the ingredients benefits is scarce. However, one study published in
the International Journal of Cosmetic Science did show a 10% concentration of Argireline to
reduce wrinkles by 30% over a 30-day period. You'll mostly find this ingredient in skin care
products designed to combat the signs of againg, such as anti-aging treatment, facial
moisturizer/lotion, concealer, eye cream and foundation.

Because Argireline is a recently discovered ingredient within the skincare arena, very little is
known regarding is safety and effectiveness. However, it should be noted that, unlike Botox,
which targets specific muscles, Argireline (assuming it works) will relax all muscles of the
face. Theoretically speaking, this could also lead to facial sagging because the
neurotransmitter release that Argireline inhibits, is also known to maintain facial firmness.
Thus, those concerned with facial sagging should approach this ingredient with caution.

2. O neuropeptid vndut sub denumirea comercial de Argireline, este utilizat ca relaxant

muscular. De asemenea, cunoscut sub numele de AHA-3.

Se numete n mod obinuit "botox ntr-un borcan" deoarece se crede c inhib eliberarea
neurotransmitorilor i relaxeaz muchii faciali - reducnd astfel liniile de expresie i
ridurile. Din pcate, dovada beneficiilor ingredientului este rar. Cu toate acestea, un studiu
publicat n Jurnalul Internaional de tiine Cosmetice a artat o concentraie de 10% a
Argireline pentru a reduce ridurile cu 30% pe o perioad de 30 de zile. Vei gsi mai ales
acest ingredient n produsele de ngrijire a pielii, concepute pentru a combate semnele de
aging, cum ar fi tratamentul anti-mbtrnire, hidratant facial / loiune, agent de ngrijire a
pielii, crem de ochi i fundaie.

Deoarece Argireline este un ingredient recent descoperit n cadrul gamei de ngrijire a pielii,
foarte puine sunt cunoscute n ceea ce privete sigurana i eficacitatea. Cu toate acestea,
trebuie remarcat faptul c, spre deosebire de Botox, care vizeaz muchii specifici, Argireline
(presupunnd c funcioneaz) va relaxa toti muchii feei. Din punct de vedere teoretic, acest
lucru ar putea duce, de asemenea, la cderea feei, deoarece eliberarea neurotransmitorului
pe care Argireline l inhib, este, de asemenea, cunoscut pentru a menine fermitatea feei.
Astfel, cei care se confrunt cu antiaging facial ar trebui s abordeze acest ingredient cu
pruden.
https://www.truthinaging.com/ingredients/acetyle-hexapeptide-8