TOXOPLASMOZA

O zoonoz cosmopolit produs de

Toxoplasma gondii.

. Protozoa C. Sporozoa O. Eucoccidiida F. Toxoplasmidae

Afectate + 350 specii

Oochisturile 12-13x10-11 m, elipsoidale; Sporularea n mediu extern; Tachizoiii 5-6x2-3 m, form de arc, multiplicare rapid, nglobai n pseudochiti; Bradizoiii semilunari, multiplicare foarte lent, nglobai n chitii intracelulari;

Diagrammatic illustration of a Toxoplasma gondii trophozoite in a macrophage of a vertebrate.

Toxoplasma gondii tissue cyst containing 8 20 parasites

Ciclul biologic

Ciclul complet feline = g.d. Variate vertebrate g.i. Infestarea g.d. Carnivorism Bradizoii, tachizoii Oochisturi In intestin = merozoii A,B,C, D,E = gametocii ou / zigot oochistul mediul exterior sporulare = 2 sporochiti x 4 sporozoii

Oochisturile mature G.i. sporozoii celulele org. endodiogenie = celule fiice tachizoii pseudochiti bradizoii chiti Localizare es. neuronal es. muscular Viscere Pp = 3-10-21 zile

Diagnostic i tratament

Coproscopic flotaie; Bioproba; Intradermoreacia, Histopatologic; Serologic - Dye test (Sabin-Feldman)

Tratament:

La pisic nu exist medicamente cu eficacitate de 100%; o combonaie de pirimetamin i sulfadiazin distruge tachizoii; Clindamicina eficient n toxoplasmoz la murine, iar la pisic reduce eliminarea de oochisturi; Sulfadiazina 30 mg/kg; Acidul folinic 5 mg/kg.

La om Corticosteroizi; Pirimetamin+sulfadiazin; Acidul folinic

SARCOSPORIDIOZELE

Produse de specii de Sarcocystis cu localizare n musculatura striat la ierbivore, omnivore, roztoare, psri, reptile, peti i om. . Protozoa C. Sporozoa O. Eucoccidiida F. Sarcocystidae

Sarcocystis bovihominis - bovine, om, S. bovicanis - bovine, cine; S. bovifelis - bovine, pisic; S. suihominis porc, om; S. suicanis porc, cine; S. ovicanis oaie, cine; S. ovifelis oaie, pisic; S. equicanis cal, cine; S. fayeri cal, cine; S. neurona cal, cal; S. cuniculi iepure, pisic; S. rileyi ra, cine; S. horvathi gin, cine

Sarcocystis cruzi oocyst

Sarcocystis cruzi oocysts in the feces of an infected dog.

A section of tongue showing three sarcocysts.

A sarcocyst in the muscle of a human.

Sarcochitii = tubii Miescher Elemente alungite efilate la extremiti Bradizoii = corpusculii Rainey in centru Metrocii la periferie Oochisturile ovoide / elipsoide 11-20 / 9-16 m Pp. 5-14 zile

Ciclul biologic

G.d. = omul, cinele, pisica mm. cu chiti i.s. bradizoii macro gamei zigotul oochistul sporuleaz in interiorul tubului digestiv mediul ext. G.i. = ierbivorele i omnivorele Migraia cu trei etape schizogonice 1- aa. Cecale, colonice, renale etc. meroni I cu tachizoii I 2 endoteliul capilar al organelor meroni IIcu tachizoii II 3 monocite meroni III cu tachizoii III Instalarea tachizoii III fibra mm. Sarcochitii = tubii Miescher

Diagnostic i tratament

Coproscopic flotaie oochisturi; Histologic Serologic

SARCOCISTI

Amprolium; Salinomicin; Oxitertraciclin; Halofuginon la capr i oaie. Pirimetamin i Trimetoprim + Sulfametoxazol la om

CRIPTOSPORIDIOZA

Protozooz a mamiferelor, psrilor, reptilelor i petilor produs de

Cryptosporidium spp. . Protozoa C. Sporozoa O. Eucoccidiida F. Cryptosporidiidae

mamifere

C. parvum, C. muris; C. baileyi, C. meleagridis; C. serpentis;

psri

reptile

peti

C. nasorum.

Oochisturile
Ovoide 4-8 / 4-6 m

Membran dubl

Ciclul biologic

Asemntor cu al altor coccidii - dar

ataarea in marginea in perie a enterocitelor n lumen se elimin oochisturi sporulate Autoinfecie Pp. = 3-4 zile

Cryptosporidium parvum: a oochist; b ciclul evolutiv

Ataarea criptosporidiilor la celula epitelial intestinal

Criptosporidie ataat la marginea n perie enterocitar

Diagnostic i tratament

Coproscopic: Flotaie metoda Anderson Preparate directe imersie Frotiuri colorate

Serologic: IFI, IFD Histologic Examenul raclatului de mucoas

Tratament:
Paramomycin