INTRODUCERE Protetica dentar, ca specializare nou aprut, este considerat un domeniu deosebit de important n medicina dentar. n cadrul acesteia, edentaia total face obiectul unor ample cercetri clinice. Aparatul dento-maxilar la edentatul total prezint o serie de modificri de form i structur, cu repercusiuni asupra suportului protezrii i al funciilor acestuia. Examinarea minuioas, clinic i paraclinic a tuturor elementelor componente ale cmpului protetic edentat total, creeaz premisele unei integrri favorabile a pieselor protetice, dar mai ales ne scutesc de eecurile terapeutice ulterioare. Posibilitile terapeutice propuse azi acestor pacieni difer foate mult. Hotrtor n acest sens sunt posibilitile materiale ale pacienilor. Medicina dentar actual, n Romnia, se regsete aproape n totalitate n sectorul privat. Rmne totui o categorie mare de pacieni, ale cror mijloace financiare nu permit tratamente stomatologice costisitoare. Programul Sanodentaprim, aflat n plin derulare, ne pune n situaia unor alternative terapeutice clasice. Chiar dac implantologia oral a ctigat cu certitudine n ziua de azi teren, fiind o component important a tratamentului proprotetic chirurgical, situaia financiar a acestor pacieni defavorizai conduce ca alternativ terapeutic spre protezarea total clasic. Rezolvarea prin metode clasice pune la grea ncercare, att rbdarea pacientului dar i pregtirea temeinic a corpului medical. n ceea ce privete cercetrile clinice, radiologice i imagistice ale cmpului protetic, personal am urmrit trei direcii: I. Pornind de la examinarea atent a elementelor cmpului protetic edentat total pentru o reuit n amprentarea acestora, mi-am propus s vizualizez ''minusurile'' aprute n realizarea clasic, n laboratorul de tehnic dentar a acestor linguri individuale. II. A doua direcie urmrit n realizarea protezelor dentare l reprezint determinarea relaiilor intermaxilare. Acurateea n verificarea corectitudinii determinrii clinice a DVO realizat prin analiza cefalometric recomand aceast investigaie imagistic ca fiind un bun mijloc de examinare a relaiilor intermaxilare n cazul pacienilor edentai total neprotezai. Aceste direcii de cercetare m-au ajutat s cresc calitatea actului terapeutic prin protezare total clasic pentru a oferi i acestor pacieni bucuria reintegrrii sociale. III. Cea de-a treia direcie a cercetrilor mele a vizat latura subiectiv a pacienilor inclui n studiu, vis- a-vis de percepia acestora fa de calitatea vieii lor dup aplicarea protezelor dentare. Succesul protezrii depinde, deci, de muli factori. Pe lng calitatea cmpului protetic, a actului medical, a modului n care medicul trateaz fiecare caz n parte, maniera de cooperare medic-pacient, hotrtoare n reuita tratamentului sunt: personalitatea pacientului, nivelul lui de cultur i inteligen, starea psihic n legtur cu acceptarea i adaptarea la protezele dentare. M bucur s constat c rezultatul muncii mele i a colegilor mai tineri, studenii, a fost apreciat de ctre pacieni, care consider c piesele protetice executate contribuie n foarte mare msur la mbuntirea calitii vieii. Iat deci, c actul medical bine condus capt valoare n ochii pacienilor, iar respectul i recunotina fa de medicul de medicin dentar este n cretere. Pe de alt parte, marea satisfacie profesional generat de cercetrile personale, const n deschiderea de noi orizonturi n mbuntirea calitii amprentrii i n acurateea determinrii relaiilor intermaxilare, dou elemente deosebit de importante n calitatea actului terapeutic oferit de protezarea total. CONTRIBUIA PERSONAL
Ipoteza de lucru/obiective Edentaia total este poate cea mai mutilant stare patologic a sistemului stomatognat, deoarece perturb toate funciile acestuia avnd consecine asupra ntregului organism. Pentru a putea vorbi de o reuit n restaurarea protetic a edentatului total trebuie s plecm de la o cunoatere amnunit a cmpului protetic, respectiv a componentelor, precum i a morfologiei acestuia. Instalarea edentaiei totale trebuie privit ca nceputul unui proces evolutiv de perturbare a echilibrului fiziologic, generat de mbtrnirea constant a structurilor anatomice ale ntregului organism, cu implicaii i asupra aparatului dento-maxilar, aspect ce poate declana un stres permanent care plaseaz mai ales persoanele n vrst ntr-o stare de labilitate psiho-somatic. Terapia edentaiei totale a fost, este i va fi mereu o preocupare a specialitilor, fiind considerat ca un domeniu complex, de o dificultate deosebit, ntruct nu se rezum numai la conceperea i realizarea unor piese protetice, ci constituie o adevarat terapie specific ce se adreseaz unei infirmiti dintre cele mai variate. Obiectivele cercetrii au fost urmtoarele: pornind de la analiza suportului muco-osos la edentatul total, s realizm linguri individuale ct mai precise pentru a putea nregistra cu maximum de exactitate suprafaa zonei de sprijin la aceti pacieni; de a vizualiza dac exist o corelaie ntre poziia papilei interincisive pe de o parte i lungimea, limea i adncimea bolii palatine pe de alta; de a verifica cu ajutorul cefalometriei laterale dac determinarea clinic a dimensiunii verticale de ocluzie a fost sau nu una corect; s nregistreze percepia pacienilor edentai total asupra calitii vieii n contextul infirmitii generate de starea de edentaie, precum i n ce msur aceasta se mbuntete la 6 luni dup purtarea protezelor dentare. Metodologie general n studiile ntreprinse pe perioada cercetrii, am inclus pacieni care fac parte din Programul Sanodentaprim, program care promoveaz Sntatea Oral prin creterea accesabilitii populaiei defavorizate la serviciile de stomatologie n cadrul parteneriatului dintre UMF Iuliu Haieganu i Primria Cluj Napoca. Grupul int se refer la persoane instituionalizate (cmine de btrni, cmine de copii, etc), pensionari, omeri i tineri pn n 26 ani ce nu realizeaz venituri. Din acest grup int de peste 1400 de pacieni, intrai n evidena Catedrei de Reabilitate Oral, Sntate Oral i Managementul Cabinetului Dentar n intervalul aprilie 2010 februarie 2012, am selectat pacienii cu edentaie total bimaxilar. Numrul pacienilor inclui n loturi pentru fiecare studiu n parte a fost diferit, n funcie de obiectivele urmrite pe segmentele de cercetare alese. Fiecrui pacient i s-a ntocmit o fi de observaie, iar apoi acetia au completat / semnat un consimmnt informat n vederea efecturii unui act medical i cte un consimmnt diferit pentru intrarea n fiecare studiu. De asemenea, metodele de lucru utilizate de-a lungul cercetrii difer pentru fiecare studiu n parte, n funcie de specificul acestuia i vor fi prezentate la capitolele respective.
Studiul 1. Analiza suportului muco-osos la edentatul total Introducere Aparatul dento-maxilar la edentatul total prezint o serie de modificri de form i structur, cu repercusiuni asupra suportului protezrii i al funciilor acestuia. Pentru a putea vorbi de o reuit n restaurarea protetic a edentatului total trebuie s plecm de la o cunoatere amnunit a cmpului protetic, respectiv a componentelor, precum i a morfologiei acestuia. De asemenea, importante sunt i particularitile individuale ale fiecrui cmp protetic edentat total. Material i metod n studiu au fost inclui 52 pacieni diagnosticai cu edentaie total bimaxilar. Pacienii au fost examiani clinic i apoi au fost amprentai dup tehnica clasic, folosind linguri standard de diverse mrimi n funcie de dimensiunile cmpurilor protetice, iar ca material de amprent s-a utilizat alginatul. Pe amprentele preliminare am trasat limitele cmpului protetic cu ajutorul unui marker, dup tehnica cunoscut. Amprentele numerotate corespunztor fiecrei persoane intrate n studiu au fost scanate la Departamentul de Ingineria Proiectrii i Robotic al Facultii de Construcii de Maini din cadrul Universitii Tehnice din Cluj-Napoca pentru a obine modele virtuale 3D, iar ulterior linguri individuale 3D ideale. Digitizarea amprentelor s-a realizat cu ajutorul unui scaner 3D portabil cu autopoziionare. Dimensiunile reduse ale amprentelor dentare precum i suprafeele neregulate au necesitat o atenie deosebit n procesul de digitizare, precum i software i hardware adecvate. Amprentele au fost digitizate cu ajutorul scanerului laser 3D VIUScan, datele obinute fiind mai apoi prelucrate n Catia V5. Pentru dimensiuni ale piesei de sub 150 mm 3 productorul scanerului garanteaz o precizie de 50 m, precizie de scanare care a fost atins i n cazul scanrii amprentelor dentare. Pe fiecare imagine scanat corespunztoare modelului virtual s-a marcat: numrul curent, nume- prenume, vrsta, sexul pacientului (M-masculin, F-feminin). Prin examinarea clinic i analiza modelului virtual 3D am urmrit caracteristicile crestelor edentate maxilare privind simetria, nlimea, limea; caracteristicile bolii palatine (adncime, lungime, lime, form, prezena/absena torusului palatin i localizarea acestuia), caracteristicile tuberozitilor maxilare (prezena retentivitilor uni, bilaterale, tuberoziti prezente, neretentive, procidente, absente); caracteristicile crestei mandibulare edentate din punct de vedere a simetriei, nlimii, limii, direciei fa de planul mediosagital, formei, precum i caracteristicile tuberculului piriform: direcie fa de creast, volum. Dup scanare, aceleai amprente au fost turnate pe loc pentru a obine modele preliminarii. Ulterior, n laboratorul de tehnic dentar, pe modelele astfel obinute s-au confecionat linguri individuale clasice. Aceste linguri individuale obinute clasic n laborator s-au scanat. Apoi, cele dou imagini 3D, reprezentnd lingura individual ideal, respectiv lingura individual clasic, s-au comparat, pentru a vizualiza ''minusurile'' aprute n realizarea clasic n laboratorul de tehnic dentar a lingurilor individuale. Rezultate Analiza suportului muco-osos la edentatul total maxilar a evideniat urmtoarele: creste edentate cu o nlime medie de 4-6 mm (75% dintre pacienii examinai), cu simetrie pstrat (80% cazuri), rotunjite (73% cazuri); bolta palatin cu o lungime cuprins ntre 4,5-4,9 cm (55% dintre cazuri), lime cuprins ntre 4- 4,9 cm (84% dinte cazuri), adncime cuprins ntre 10-14 mm (56% dintre cazuri), fr torus palatin prezent, cu forma literei U; tuberozitile maxilare au fost n 95% dintre cazuri prezente, i cel mai frecvent erau retentive bilateral n 70% din cazuri. La mandibul, cmpul protetic edentat total a fost caracterizat de creste edentate simetrice (42 cazuri), n forma de U (34 cazuri), iar direcia crestei a fost n 38 de cazuri descendent spre distal. Crestele edentate au prezentat o nlime medie n 34 de cazuri, respectiv o lime medie n 38 de cazuri. Ca urmare a centralizrii datelor, s-a constatat o direcie orizontal a tuberculului piriform n 38 de cazuri, respectiv o direcie oblic n 14 cazuri. n ceea ce privete volumul tuberculului piriform n 8 cazuri acesta a fost voluminos, n 32 de cazuri acesta a avut un volum mediu, iar n 12 cazuri acesta a fost redus ca volum. Dup analiza suportului muco-osos, n partea a doua a studiului, am fcut o analiz a deviaiei care s pun n eviden, prin instrumente matematice, diferena ntre suprafeele lingurilor individuale clasice i ideale, scanate i aliniate. Diferenele semnificative aprute dup interpretarea hrilor de culori au fost evideniate la maxilar n zona tuberozitilor, iar la mandibul, n zona tubercului piriform.
Studiul 2. Papila interincisiv indicator al resorbiei maxilarului n edentaia total Introducere Odat cu pierderea unitilor dentare la edentat procesul alveolar, numit de Beltrami i os dentar, sufer remanieri, osul de neoformaie umplnd alveola i astfel devine creasta alveolar, sau cum mai apare n literatur, creasta edentat. Imediat dup pierderea unitilor masticatorii, osul maxilar sufer fenomene de atrofie i resorbie osoas. Aceste fenomene vor influena negativ stabilitatea viitoarelor piese protetice. Material i metod n studiu au fost inclui 52 pacieni diagnosticai cu edentaie total. Am inclus n studiu doar pacienii cooperani i care, n urma examenului clinic prezentau: arcade dentare n form de U simetria arcadelor pstrat Au fost exclui din studiu: pacienii necooperani pacienii care au purtat anterior proteze dentare pacienii care n urma examenului clinic endobucal au prezentat: alt form a arcadelor dentare dect U arcade asimetrice absena bridelor canine prezena torusului maxilar n timpul examenului clinic am surprins pe obiectivul aparatului foto poziia papilei interincisive, iar n finalul examinrii fiecare din cei 52 de pacieni au fost amprentai, n vederea confecionrii modelelor de studiu. Modelele astfel obinute au fost scanate la Departamentul de Ingineria Proiectrii i Robotic al Facultii de Construcii de Maini din cadrul Universitii Tehnice din Cluj-Napoca i s-au realizat modele de studiu 3D. 1. Determinarea clinic i pe fotografie a poziiei papilei interincisive: posterior (pe versantul palatinal al crestei edentate n zona frontal); pe mijlocul crestei edentate; anterior (pe versantul vestibular al crestei edentate frontale). Studiul modelelor 3D obinute dup scanarea modelelor de studiu a cuprins urmtoarele msurtori: a. Lungimea bolii palatine (LBP): de la tangent la proeminena maxim de pe versantul vestibular al crestei edentate n dreptul frenului buzei superioare pn la linia tangent la faa distal a tuberozitilor n anul retrotuberozitar. b. Adncimea bolii palatine la nivel molar (ABP): adncime msurat la unirea treimii mijlocii cu treimea distal a palatului dur. c. Limea bolii palatine (lBP): limea maxim la unirea treimii mijlocii cu treimea anterioar pe versanii externi ai crestei edentate. Rezultate Cei 52 de pacieni luai n studiu (26 femei, 26 barbai), aveau vrste cuprinse ntre 40 i 85 ani. Variaia poziiei papilei la sexul feminin arat n felul urmtor: La o vechime a edentaiei cuprins ntre 0 i 2 ani predomin poziia pe mijlocul crestei n 13 cazuri, poziia posterioar n 5 cazuri. Nu exist nici un caz n care poziia papilei s fie anterior. La o vechime a edentaiei cuprins ntre 3 i 5 ani predomin poziia pe mijlocul crestei n 3 cazuri. Nu exist poziie anterioar sau posterioar la nici unul din cazuri la aceast vechime a edentaiei. La o vechime a edentaiei de peste 5 ani am observat 4 cazuri n care poziia papilei era una anterioar, respectiv 1 caz n care papila avea o poziie pe mijlocul crestei. La femei exist o asociere semnificativ statistic ntre poziia papilei i grupele de edentaie, testul exact al lui Fisher, p=0.002<0.05-semnificativ statistic. Variaia poziiei papilei la sexul masculin relev urmtoarele: La o vechime a edentaiei cuprins ntre 0 i 2 ani predomin poziia pe mijlocul crestei n 12 cazuri, poziia posterioar n 5 cazuri i 2 cazuri n care poziia papilei a fost una anterioar. La o vechime a edentaiei cuprins ntre 3 i 5 ani predomin poziia anterioar n 3 cazuri, poziia pe mijlocul crestei 1 caz. Nu exist o poziionare posterioar la nici un caz la aceast vechime a edentaiei. La o vechime a edentaiei de peste 5 ani am observat 1 caz n care poziia papilei era una anterioar, respectiv 2 cazuri n care papila avea o poziie pe mijlocul crestei. Nu s-a semnalat o poziionare posterioar la nici un caz la aceast vechime a edentaiei. La brbai nu am avut suficiente dovezi pentru a pune n eviden o asociere semnificativ statistic ntre poziia papilei i grupele de edentaie, testul exact al lui Fisher, p=0.094>0.05-nesemnificativ statistic. Indicatorul LBP (lungime bolta palatin) are valori medii n scdere de la primul interval de vechime pn la ultimul. Indicatorul lBP (lime bolta palatin) are valori medii n scdere de la primul interval de vechime pn la ultimul. Indicatorul ABP (adncime bolta palatin) are valori medii n scdere de la primul interval de vechime pn la ultimul.
Studiul 3. Verificarea corectitudinii determinrii clinice a dimensiunii verticale de ocluzie cu ajutorul cefalometriei laterale Introducere Determinarea dimensiunii verticale de ocluzie este o etap deosebit de important n tratamenntul edentaiei totale prin proteze dentare. Literatura de specialitate propune astzi o multitudine de tehnici, unele mai simple, altele mai complexe. Au fost propuse multe metode pentru a determina dimensiunea vertical. Fie c vorbim de utilizarea poziiei fiziologice de repaus, de deglutiie, de probe fonetice, de msurtori faciale, nici una din aceste metode nu stabilete o dimensiune vertical matematic corect. Preocuparea multor autori a fost orientat spre gsirea unor modaliti de pstrare a acestei dimensiuni dinainte de pierderea unitilor dentare. n acest sens, Swenson propune confecionarea unei mti de acrilat, pstrnd astfel dimensiunile faciale ale pacienilor. Silverman recomand tatuarea pe mucoasa fix n zona frontal att la maxilar, ct i la mandibul a dou puncte. Msurarea distanei dintre ele n poziia de R.C. i I.M. va fi nregistrat i pstrat n fia fiecrui pacient. Material i metod Material (pacieni) n studiu au fost inclui 19 pacieni cu vrsta cuprins ntre 60-69 ani, care prezentau edentaie total bimaxilar, cu o vechime a edentaiei cuprins ntre 0 i 2 ani. Am inclus n studiu: pacienii cooperani pacienii care n urma examenului clinic al extremitii cefalice la inspecie din norma lateral prezentau un profil drept pacienii pentru care nu am avut nregistrat i pstrat DVO anterior strii de edentat (documente preextracionale) pacienii cu simetrie facial pstrat Au fost exclui din studiu: pacienii necooperani pacienii care au purtat anterior proteze dentare pacienii care n urma examenului clinic al extremitii cefalice la inspecie din norma lateral prezentau un profil convex sau concav pacienii cu malformaii ale masivului facial. Metoda de lucru 1. Determinarea clinic a dimensiunii verticale de ocluzie Pacienii au fost aezai pe fotoliul dentar cu trunchiul n poziie vertical i cu capul nesprijinit n tetier. Totodat am asigurat o atmosfer linitit n cabinet, cutnd s nlturm orice stare de tensiune pe care pacienii ar fi putut s o aib. Dimensiunea vertical de ocluzie s-a determinat pornind de la dimensiunea vertical de repaus. 2. A urmat apoi realizarea cefalometriilor laterale pe suport electronic i analiza acestora, urmnd protocolul de analiz cefalometric. Axiograful computerizat Cadiax, prin softul aferent, are posibilitatea de a realiza i analiza cefalometric, prin activarea sistemului Cadias. Rezultate Analiza cefalometriilor laterale pentru pacienii luai n studiu a artat c n doar 7 cazuri DVO determinat clinic a fost una corect. n 9 cazuri DVO a fost supradimensionat, iar n 3 cazuri s-a constatat c DVO a fost subdimensionat. Cefalometriile laterale executate persoanelor de sex masculin arat o determinare corect a DVO n 5 cazuri. Supraevaluarea clinic s-a produs n 4 cazuri, iar subdimensionarea apare n 3 cazuri. La sexul frumos n schimb DVO clinic a fost stabilit corect n 2 cazuri, iar n 5 cazuri DVO a fost supradimensionat clinic.
Studiul 4. mbuntirea calitii vieii la pacientul edentat total dup protezare Introducere n 1998, OMS definete calitatea vieii astfel: calitatea vieii este dat de percepia indivizilor asupra situaiilor lor sociale n contextul sistemelor de valori culturale n care triesc, i n dependen de propriile lor trebuine, standarde i aspiraii. O definiie mai complex este dat de I. Mrginean n 2002. Domnia sa, definea calitatea vieii prin ansamblul elementelor care se refer la situaia fizic, economic, social, cultural, politic, de sntate etc. n care triesc oamenii, coninutul i natura activitilor pe care le desfoar, caracteristicile relaiilor i proceselor sociale la care particip, bunurile i serviciile la care au acces, modelele de consum adoptate, modul i stilul de via, evaluarea mprejurrilor i rezultatelor activitilor care corespund ateptrilor populaiei, precum i strile subiective de satisfacie i insatisfacie, fericire, frustare, etc. Totui, declaraiile celor investigai evideniaz o mare importan acordat sntii n aprecierea fcut de ei, chiar dac aceast apreciere este de cele mai multe ori subiectiv. Material i metod n studiu au fost inclui 120 pacieni, diagnosticai cu edentaie total bimaxilar. Am inclus n studiu doar pacienii cooperani i care la examenul clinic prezentau edentaie total bimaxilar, neprotezat. Au fost exclui din studiu pacienii necooperani precum i pacienii care au purtat anterior proteze dentare. Pacienii edentai total bimaxilar au completat 2 chestionare identice alctuite din 23 itemi. Ambele chestionare urmresc s surprind percepia pacienilor cu privire la tulburrile masticatorii, fonatorii, fizionomice i psihice induse de starea de edentaie, modul n care aceste aspecte: influeneaz starea de sntate oro-dentar influeneaz calitatea vieii contribuie la modificarea n sens negativ a imaginii i a stimei de sine influeneaz viaa social, viaa profesional determin apariia unor comportamente evitative (pacienii nu vorbesc n public, nu mnnc dect n familie, etc) pot fi corectate prin tratament de specialitate, prin purtarea pieselor protetice. Primul chestionar a fost completat de ctre pacieni anterior confecionrii protezelor dentare i conine datele personale ale fiecrui repondent, precum i intervalul scurs (n luni) de la pierderea ultimelor uniti dentare, iar cel de-al doilea chestionar a fost oferit spre completare la 6 luni dup confecionarea, aplicarea protezelor i finalizarea etapelor de retu efectuate la nivelul pieselor protetice. Rezultate Absena unitilor dentare determin n cele mai multe cazuri o imposibil secionare a alimentelor i o triturare deficitar a acestora. Astfel, majoritatea pacienilor chestionai ntmpin reale dificulti n actul masticator (83-foarte multe, 37-multe). Dup protezare, raportul se modific substanial: 74 persoane din totalul de 120 chestionate semnaleaz dificulti puine n actul masticator sau chiar nesemnificative - 9 cazuri. Sunt, totui, pacieni care semnaleaz dificulti n actul masticator i dup aplicarea protezelor dentare i efectuarea retuurilor necesare (33 - multe i doar 4 persoane - f multe). Situaia oro-dentar a pacienilor intrai n studiul anterior protezrii, impunea preponderent consumul de alimente lichide, precum i a celor moi-pstoase. Ulterior, la 6 luni dup aplicarea pieselor protetice, consistena alimentelor ingerate s-a modificat treptat, pacienii chestionai fcnd meniunea c ingereaz, pe lng alimente moi pstoase, i alimente solide (33 cazuri). Ca urmare a dificultilor pe care pacienii le ntmpin n actul masticator, pacienii chestionai au fost nevoii s nghit alimentele fr a le tritura suficient (foarte des - 33 cazuri, respectiv des - 87 cazuri). Odat cu intrarea n uz a protelor dentare, 5 pacieni chestionai rspund c n rare cazuri sunt nevoii s nghit mncarea nemestecat, iar 114 reusesc s rectige plcerea de a efectua actul masticator. O persoan nu a raspuns la aceast ntrebare dup aplicarea protezelor dentare. Dup extracia ultimelor uniti dentare, treptat, fizionomia feei s-a modificat n ru la nivelul obrajilor i buzelor foarte mult-29 cazuri, respectiv mult-91 cazuri. Dup aplicarea protezelor dentare aspectul fizionomic al feei s-a mbuntit ca percepie mult -84 cazuri, foarte mult-36 cazuri. Treptat, dup pierderea unitilor dentare, 66 dintre pacienii chestionai apreciaz c fizionomia feei este n foarte mare msur afectat, n timp ce 54 dintre pacieni conider c faciesul este mbtrnit n mare msur. Purtarea protezelor dentare confer pacienilor un aspect ntinerit n foarte mare msur - 80 cazuri, n mare msur - 36 cazuri. La aceeai ntrebare, doi pacieni percep ntinerirea facial n mic msur, n timp ce ali doi pacieni nu percep modificri semnificative n ceea ce privete aspectul ntinerit al extremitii faciale. Tulburrile de vorbire i pronunie, odat cu pierderea dinilor, sunt percepute ca fiind multe - 95 cazuri, respectiv foarte multe - 25 cazuri. Dificultile de vorbire i pronunie s-au mbuntit mult - 76 cazuri i foarte mult - 44 cazuri la 6 luni dup aplicarea pieselor protetice. Pierderea unitilor dentare a contribuit la modificarea n sens negativ a imaginii i a stimei de sine n 22 cazuri - foarte mult, mult - 91 cazuri i puin n 7 cazuri. Prin purtarea protezelor dentare pacienii i-au recptat ncrederea n propria persoan, fcnd meniunea c piesele protetice le-au modificat n sens pozitiv imaginea (26 cazuri - foarte mult, mult - 90 cazuri i puin n 4 cazuri). n ce privete viaa social i inseria n grupul de prieteni, acestea sunt afectate odat cu pierderea unitilor dentare foarte mult - 36 cazuri, respectiv mult - 84 cazuri. Purtarea protezelor dentare l face pe pacientul purttor al acestor piese protetice un participant activ la viaa social, mbuntindu-i-o (foarte mult - 39 cazuri, respectiv mult - 81 cazuri). Viaa de cuplu, anterior protezrii, a fost afectat: foarte mult - 31 cazuri, mult - 30 cazuri, puin - 44 cazuri i nesemnificativ - 15 cazuri. Ulterior, ca urmare a purtrii protezelor dentare, acest aspect s-a mbuntit foarte mult - 32 cazuri, mult - 49 cazuri, puin- 21 cazuri, nesemnificativ - 18 cazuri. Starea de sntate oro-dentar, dup pierderea unitilor dentare, este perceput ca fiind precar - 104 cazuri, respectiv satisfctoare - 16 cazuri. Dup protezare, starea de sntate oro-dentar este apreciat ca fiind foarte bun - 5 cazuri, bun - 107 cazuri i satisfctoare - 8 cazuri. Subiecii chestionai apreciaz n ansamblu calitatea vieii dup pierderea unitilor dentare ca fiind precar - 106 cazuri i n 14 cazuri ca fiind satisfctoare. Calitatea vieii dup aplicarea pieselor protetice este perceput ca fiind foarte bun - 2 cazuri, bun - 110 cazuri i satisfctoare - 8 cazuri. Pacienii chestionai anterior protezrii consider c tratamentul stomatologic va contibui la mbuntirea calitii vieii n foarte mare msur - 38 cazuri, respectiv n mare msur - 82 cazuri. Rezultatul muncii noastre a fost apreciat de ctre pacienii care au afirmat c piesele protetice au contribuit la mbuntirea calitii vieii: foarte mult - 74 cazuri, respectiv mult - 46 cazuri.
CONCLUZII GENERALE
1. Cunoaterea i examinarea amnunit a elementelor morfo-structurale ale cmpului protetic mandibular edentat total ajut practicianul n stabilirea cu exactitate a zonei de sprijin i de succiune. 2. Analiza suportului muco-osos ofer o bun perspectiv asupra prognosticului pentru fiecare caz n parte. 3. Analiza suportului muco-osos prin rezultatele obinute constituie un material didactic util pentru a pune n eviden marea variabilitate a cmpurilor protetice examinate. 4. Compararea scanrilor celor dou linguri individuale clasice, respectiv 3D arat necesitatea imperioas de realizare a unor linguri individuale ideale. 5. Realizarea lingurilor individuale ideale 3D ofer premisele unei amprentri finale de mare acuratee. 6. Papila interincisiv poate fi considerat un indicator incert al resorbiei maxilare n cazul pacienilor edentai total. 7. Limea bolii palatine (lBP) poate fi considerat marker al resorbiei osoase maxilare, la ntreg lotul studiat, acest indicator scade ca valoare medie odat cu creterea vechimii edentaiei totale. 8. Adncimea bolii palatine (ABP) este un indicator al resorbiei osoase maxilare, valorile acestui indicator scznd odat cu creterea vechimii edentaiei. 9. Lungimea bolii palatine (LBP) poate fi considerat, de asemenea, indicator al resorbiei maxilare. 10. Acurateea n verificarea corectitudinii determinrii clinice a DVO realizat prin analiza cefalometric recomand aceast investigaie imagistic ca fiind un bun mijloc de examinare a relaiilor intermaxilare n cazul pacienilor edentai total neprotezai. 11. Analiza cefalometric elimin erorile umane i criteriile subiective ale medicului n stabilirea corect a DVO. 12. Analiza cefalometric este o metod obiectiv n determinarea DVO. 13. Analiza cefalometric trebuie s fie utilizat n faza clinic de determinare a relaiilor intermaxilare la edentatul total neprotezat. 14. Hotrtoare n reuita tratamentului sunt personalitatea pacientului, nivelul lui de cultur i inteligen, starea psihic n legatur cu acceptarea i adaptarea la protezele dentare. 15. Niciodat un edentat total protezat prin proteze clasice dentare nu va putea avea capacitatea masticatorie a unui dentat. 16. Protezele dentare clasice, dac sunt corect confecionate, rspund n mare msur cerinelor fizionomice. 17. Cu ajutorul tratamentului prin proteze dentare pacientul i rectig stima de sine, putndu-se reintegra n viaa social.
ORIGINALITATEA SI CONTRIBUTIILE INOVATIVE ALE TEZEI
Cercetarea de fa conine o serie de elemente care-i confer un caracter original i inovativ, prin aportul adus etapelor clinice de realizare a pieselor protetice. Studiile din cadrul tezei de doctorat contribuie la perfecionarea celor mai importante faze clinice din algoritmul terapeutic, influennd pozitiv integrarea protezelor dentare n funcionalitatea aparatului dento- maxilar. Compararea scanrilor celor dou linguri individuale clasice, respectiv analiza fiierelor 3D, evideniaz reale deficiene n confecionarea lingurilor individuale dup tehnica clasic n laboratorul de tehnic dentar. n urma cercetrii ntreprinse, propun confecionarea unor linguri individuale ideale cu ajutorul software-ului 3D CATIA V5 pentru a crea premisele unei amprentri funcionale perfecte. Metoda propus se ncadreaz perfect n utilizarea mijloacelor moderne i inovatoare de tratament care au cunoscut o dezvoltare important n ultimii ani. De asemenea, cercetarea a demonstrat c analiza cefalometric este o metod imagistic obiectiv n stabilirea cu acuratee a corectitudinii determinrii clinice a dimensiunii verticale de ocluzie. Tocmai de aceea consider c determinarea DVO cu ajutorul analizei cefalometrice ar trebui s fie o etap obligatorie n tratamentul edentatului total prin protezarea clasic. Buna precizie n determinarea DVO cu ajutorul cefalometriei laterale constituie astfel un instrument obiectiv n terapia edentaiei totale. Prin urmare, cercetrile efectuate n cadrul acestei teze doctorale deschid noi perspective spre mbuntirea etapelor clinice n elaborarea pieselor protetice, cu aplicabilitate n mod curent i pe scar larg, astfel nct proteza dentar clasic s asigure un status sanogen dentar de excepie.
DOCTORAL SCHOOL
SUMMARY OF THE PHD. THESIS Clinical, radiological, and imagistic research of the totally endentulous prosthetic field PhD Student Dan, Buhel PhD Scientific Coordinator Floarea, Fildan
ClujNapoca, 2013
SUMMARY
INTRODUCTION 13 CURRENT STATE OF KNOWLEDGE
1. The totally edentulous prosthetic field 17 1.1. General considerations 17 1.2. The jaw prosthetic field 17 1.2.1. The support area 17 1.2.1.1. The bone substrate 17 1.2.1.2. The mucous substrate 20 1.2.2. The succion area 20 1.2.2.1. The passive mobile mucosa 20 1.2.2.2. The mobile mucosa 20 1.3. The prothetic field of the jaw 20 1.3.1. The support area 20 1.3.1.1. The bone substrate 20 1.3.1.2. The mucous substrate 21 1.3.2. The succion area 22 1.3.2.1. The passive mobile mucosa 22 1.3.2.2. The mobile mucosa 22 2. Disorder of the main functions of the dento-maxilar apparatus of the TE TTEedentulous patient 23 2.1. Chewing disorders 23 2.2. Physiognomic disorders 24 2.3. Phonetic disorders 24 2.4. Psychic disorders 25 3. Determining the vertical dimention of the lower floor of the face 27 3.1. General considerations 27 3.2. Definitions 27 3.3. Determining conditions 28 3.3.1. Patient's condition 28 3.3.2. Preprothetical conditions 28 3.3.3. Analysis of the occlusion patterns 29 3.4. Methods of determining the vertical dimention of the occlusion 30
PERSONAL CONTRIBUTION
1. Working hypothesis /objectives 37 2. General methodology 37 3. Study 1 The analysis of the mucous-bone support in the totally edentulous patient 39 3.1. Introduction 39 3.2. Working hypothesis/Obiectives 41 3.3. Material and method 42 3.4. Results 45 3.5. Discutions 53 3.6. Conclusions 56 4. Study 2 - The interincisive papilla indicator of the jaw's reabsorbtion in the full edentention 57 4.1. Introduction 57 4.2. Working hypothesis/objectives 58 4.3. Material and method 58 4.4. Results 64 4.5. Discutions 73 4.6. Conclusions 74 5. Study 3 - Verification of the correctness of the clinical determination of the vertical dimention of occlusion by means of the lateral cefalometrics 77 5.1. Introduction 77 5.2. Working hypothesis/objectives 78 5.3. Material and method 79 5.4. Results 88 5.5. Discutions 89 5.6. Conclusions 91 6. Study 4 - The improvement of the quality of life in the totally edentulous patient after prosthesis 93 6.1. Introduction 93 6.2. Working hypothesis/objectives 96 6.3. Material and method 96 6.4. Results 97 6.5. Discutions 104 6.6. Conclusions 108 7. General conclusions 109 8. Originalitaty and inovative contributions of the thesis 111
ABREVIATIONS 11 ANNEXED 113 REFERENCES 123
KEYWORDS: totally edentulous, custom tray, vertical dimension of occlusion, prosthetic rehabilitation, oro-dental health, chewing disorders, psysionomical disorders, phonetic disorders, psychiatric disorders, quality of life
INTRODUCTION
Dental prosthetics, asa a newly emerging specialty, is considered an extremely important field in dental medicine. Within this field, totally edentation makes the study of ample clinical research. The dento-maxillary apparatus in the totally edentulous patient presents a series of modifications in form and structure, with repercussions over the support of the prosthesis and its function. Careful examination, clinical and paraclinical of all the composing elements of the totally edentulous prosthetic field creates the premises of a favorable integration of the prosthetic pieces, but mostly prevent us from ulterior therapeutic failures. The therapeutic possibilities proposed to these patients nowadays differ considerably. A decisive factor in this sense are the material means of the patients. Currently, dental medicine in Romania belongs o the private sector. A large category of patients remains, however, whose financial means do not allow costly stomatological treatments. The Sanodentarprim program, currently underway, confronts us with classical therapeutic alternatives. Even through oral implantology has certainly gained terrain nowadays, being an important component of the surgical prosthetic treatment, the financial situation of these disvavored patients leads towards the classical full prosthesis as a therapeutic alternative. Solving the problem through classical methods puts to the test both the patient's patience and the thorough training of the medical body. As far as clinical, radiological, and imagistic research of the prothetic fied is concerned, I have personally followed three directions: I. Starting from the careful examination of the elements of the totally edentulous prosthetic field, in order to succeed in printing these, I have set out to visualize the "minuses" which have shown up in the classical approach, in the dental technique laboratories of these individual custom trays. II. The second direction followed in creating the dental prosthesis is represented by the determination of intermaxillary relations. The accuracy in verifying the correctness of the clinical determining of DVO, carried out through the cefalometric analysis recomnds this imagistic investigation as a good means to examine the intermaxilary relations in the case of totally edentulous patients without prosthesis. These directions of research have helped me increase the quality of the therapeutic act through classical total prosthesis in order to offer these patients as well the joy of social reintegration. III. The third direction of my research has aimed for the subjective side of the patients included in the stdy, regarding their perception towards the quality of their life after the application of the denatl prosthesis. The succcess of the prosthesis depends, thus, on many factors. Besides the quality of the prosthetic field, of the way in which the doctor treats every individual case, the doctor-patient manner of cooperation, decisive in the success of the treatment are: the patient's personality, their level of culture and intelligence, the psychological state regarding accepting and adapting to the dental prosthesis. I am happy to see that the result of my work and of my younger colleagues, the students, was appreciated by many patients who consider that the prosthetic pieces executed contribute to a great extent to the improvement of the quality of life. The well conducted medical act does, hence, gain value in the eyes of the patients, and their respect and gratitude towards the dental medicine doctor is on the rise. On the other hand, the great professional satisfaction generated by personal research consists in the opening of new horizons in the improvement of the quality of imprinting and the accuracy of determining the intermaxilary relations, two very important elements in the quality of the therapeutic act offered by full prosthesis. PERSONAL CONTRIBUTION
Working hypothesis/obiectives Full edentation is perhaps the most mutilating pathological state of the stomatognat system, as it perturbs all the latter's functions, bearing consequences on the entire body. In order to speak about success in the prosthetic restoring of the totally edentulous patient, we must start from the thorough knowledge of the prosthetic field, of itsrespective components, as well as its morphology. The onset of the full edentation must be regarded as the beginning of an evolutive process of perturbing the physiological balance, generated by the constant aging of the anatomical structures of the entire organism, with implications over the dento-maxillary apparatus, an aspect which can set off a permanent state of stress, which put older persons in particular in a state of psycho-somatic lability. The therapy of full edentation was, is and will always be a preoccupation of the specialists, being considered a complex domain, of particular difficulty, as it does not limit itself to the conception and creation of certain prostehetic pieces alone, but constitutes a true specific therapy which addresses one of the most varied infirmities. The objectives of the research were the following: starting from the analysis of the mucous-bone support in the totally edentulous patient, we should create individual custom trays, as precise as possible, in order to be able to record, with maximum exactness the surface of the support are in these patients; to visualize whether or not there exists a correlation between the position of the interincisive papilla on the one hand and the length, width, and depth of the pallatal arch, on the other; to varify with the hep of lateral cefalometrics if the clinical determination of the vertical dimention of the occlusion was a correct one or not; to record the perception of the totally edentulous patients of the quality of life in the context of the infirmity generated by the edentulous state, as well as the extent to which this perception improves six months after wearing thr dental prosthesis.
General Metodology In the studies carried out during my research, I have included patients who are part of the Sanodentaprim Program, a program which promotes Oral Health by increasing the disadvantaged population's access to stomatological services as part of the partnership between UMF Iuliu Haieganu and the Cluj Napoca Town Hall. The target group refers to institutionalised persons (old persons homes, children's homes, etc), retired people, unemployed people, and young people under the age of 26 who do not have any income. From this target group of over 1400 patients, registered with the Faculty of Oral rehabilitation, Oral Health, and the Management of the Dental Office, during April 2010-February 2012, we have selected patients with bimaxillary full edentation. The number of patients included in the lots for each particular study was different, depending on the objectives followed on the chosen segments of research. Each patient had an observation chart drawn out, and they subsequently filled out/signed an informed consent towards the performing of a medical act and a different consent form each, for entering each study. Also, the working methods used throughout the research differ for each particular study, depending on the latter's specificity, and will be presented in the respective chapters.
Study 1. The analysis of the mucous-bone support of the totally edentulous patient Introduction The dento-maxillary apparatus in the totally edentulous patient presents a series of modifications in form and structure, with repercussions over the support of the prosthesis and its functions. In order to speak about success in the prosthetic restauration of the totally edentulous patient, we must depart from a detailed knowledge of the prosthetic field, and its respective components, as well as from its morphology. Also of importance are the individual particularities of each totally edentulous prosthetic field. Material and method 52 patients diagnosed with full bimaxillary edentation have been included in the study. The patients have been examined clinically and were then printed after the classical technique, using standard custom trays of various sizes depending on the size of the prosthetic fields; alginate was used as printing material. On the preliminary prints, we have traced the limits of the prosthetic field by means of a marker, after the known technique. The prints numbered according to each person who has entered the study were scanned in the Department of the Engineering of Projection and Robotics of the Faculty of Machine Constructions within the Technical University in Cluj-Napoca in order to obtain virtual 3D models, and later 3D ideal individual custom trays. The digitization of prints was realized with the help of a portable 3D scanner with self-positioning. The reduced dimentions of the dental prints, as well as the irregular surfaces necessitated special attention in the digitization process, as well as the proper software and hardware. The prints were digitized with the help of the 3D laser scanner VIUScan, the date obtained being then processed in Catia V5. For dimentions of the piece under 150 mm 3, the producer of the scanner guarantees a precision of 50 m, a scaning precision which was attained in the case of scanning dental prints as well.
On each image scanned corresponding with the virtual model, the following were marked: the current name, surname, name, age sex of the patient. ( M-masculin, F-feminin). Through clinical examination and analysis of the 3D virtual model, we have followed the traits of the maxillary edentulous crests regarding the symmetry, height, width; the characteristics of the pallatine arch (depth, length, width, shape, presence/absence of the pallatine torus and its localization), the characteristics of the maxillary tuberosities (the presence of uni.bilateral retentiveness, tuberosities present, nonretentive, procidentous, absent); the characteristics of the mandibular edentulous crest from the point of view of the symmetry, height, width, direction towards the mediosagital plan, shape, as well as the characteristics of the piriform tubercule: direction in relation to the crest, volume.
After scanning, the same prints were cast on the spot in order to obtain preliminary models. Subsequently, in the dental technique laboratory, classical individual custom trays were thus made. These individual custom trays obtained clasically in the laboratory were scanned. Then, the two 3D images, representing the ideal custom tray, and, respectively, the classical custom tray, were compared, in order to visualize the "minuses" shown up in the classical realization in the dental technique laboratory of the custom trays. Results The analysis of the mucous-bone support in the totally edentulous maxillary patient has highlighted the following: edntulous crests with a medium height of 4-6 mm (75% of the examined patients), with preserved symmetry (80% of the cases), rounded (73% cases); the pallatine arch with a length between 4,5-4,9 cm (55% of the cases), width between 4-4,9 cm (84% of the cases), depth between 10-14 mm (56% of the cases), without pallatine torus present, in the shape of the letter U; the maxillary tuberosities were present in 95% of the cases, and most frequently were retentive bilaterally in 70% of the cases. In the mandibula, the totally edentulous prosthetic field was characterised by symmetrical edented crests (42 cases), in U shape (34 cases), and the direction of the crest was in 38 cases descendent towards distal. The edentulous crests presented a medium height in 34 cases, a medium width in 38 of the cases. As a consequence of centralising the data, a horizontal direction of the piriform tubercule was noted in 38 cases, and an oblique direction in 14 cases, respectively. Regarding the volume of the piriform tubercule in 8 cases this was voluminous, in 32 cases, it had a medium volume, and in 12 cases, it was reduced in volume. After the analysis of the mucous-bone support, in the second part of the study, I performed an analysis of the deviation which would highlight, through mathematical instruments, the difference between the surfaces of the individual custom trays, classical and ideal, scanned and aligned. The significant differences which have shown up after the interpretation of the color maps have been highlighted at the maxillary in the area of the tuberosities, and in the mandibulla, in the area of the piriform tubercule.
Study 2. The interincisive pupilla indicator of the reabsorption of the maxillary in the full edentation Introduction Along with the loss of dental units in the edentulous patient, the alveolar process, called by Beltrami dental bone as well, suffers changes, the neoformation bone filling the alveola and thus becomes the alveolary crest, or as it appears in the literature, the edentulous crest. Immediately after the loss of masticating units, the macillary bone suffers pheoemenons of atrophy and bone reabsortion. These phenonema will influence negatively the stability of future proteic pieces. Material and method 52 pacieni diagnosed with full edentation have been included in the study. I have included in the study only compliant patients and who, following the treatment, presented: U shaped dental arcades the symmetry of the arcade maintained The following have been excluded from the study: uncooperative patients patients who have previously worn dental prosthesis pacients who following the endobuca clinical exam have presented: another shape of the dental arcades than U asymmetrical arcades the absence of canine brides the presence of the maxillary torus During the clinical exam I have captured on the camera lens the position of the interincisive papilla, and at the end of the examination, each of the 52 patients have been printed, with the purpose of making study models. The models thus obtained were scanned in the Department of Project Engineering and Robotics of the Faculty of Machine Construction within the Technical University in Cluj-Napoca, and 3D study models were created. 1. The clinical determination and on the photograph ofthe interincisive papilla position: posterior (on the pallatinal side of the edentulous crest in the frontal zone); in the middle of the crest edentulous; anterior (on the vestibular side of the frontal edentulous crest).
The study of the 3D models obtained after scanning the study models comprised the following measurements: a. The length of the pallatine arch (LPA): from the tangent to the maximum prominence on the vestibulary side of the edentulous crest in line with the upper lip up to the tangent to the distal face of the tuberosity in the retrotuberose ditch. b. The depth of the pallatine arch (DPA): depth measured the union of the middle thirs with the distal third of the hard pallate. c. The width of the pallatine arch (WPA): the maximum width at the union of the miffle third with the anterior theird on the external sides of the edentulous crest. Results The 52 patiente taken into the study (26 women, 26 men) had ages between 40 and 85 years. The variation of the position of th papilla in the female gender looks ad follows: When the indentation is 0 to 2 years old, the position in the middle of the crest predominates in 13 cases, the posterior position in 5 cases. There is no case in which the position of the papilla is anterior. When the indentation is between 3 and 5 years old, the position in the middle of the crest predominates in 3 cases. There is no anterior or posterior position in any of the cases when the edentation is this old. When the edentation is over 5 years old, I have noticed cases in which the position of the papilla was an anterior one, and one case, respectively, in which the papilla had a position in the middle of the crest. In women, there is a significant association between the position of the papilla and the edentulous groups, Fisher's exact test, p=0.002<0.05, statistically significant. The variation of the position of the papilla in the masculine gender reveals the following: When the edentation is between 0 and 2 years old, the position on the middle of the crest predominates in 12 cases, the posterior position in 5 cases and 2 cases in which the position of the papilla was an anterior one. When the edentation is between 3 and 5 years old, the anterior position predominates in 3 cases, the position on the middle of the crest, 1 case. There is no posterior position in any of the cases when the edentation is this old. When the edentation os over 5 years old, I have noted a case in which the position of the papilla was an anterior one, and two cases, respectively, in which the papilla had a position in the middle of the crest. No posterior position in any of the cases when the edentation is this old. In men, we did not have sufficient evidence in order to highlight a statistically significant association between the position of the papilla and the edentation, Fisher's exact test, p=0.094>0.05- statistically insignificant. The LPA indicator (length of the pallatine arch) has middle values decreasing from the first interval of age until the last. The (DPA) (depth of the pallatine arch) indicator has middle values decreasing from the first interval of age until the last.
Study 3. Verifying the correctness of the clinical determination of the vertical dimension of occlusion with the help of lateral cefalometry Introduction Determining the vertical dimention of occlusion is an especially important stage in the treatment of full edentation through dental prosthesis. The specialist literature proposes today a multitude of techniques, some more simple, others more complex. Many methods were suggested for determining the vertical dimension. Whether we speak about using the physiological position of rest, of swallowing, of phonetic proofs, facial measurements, none of these methods establishes a mathematically correct vertical dimension. Many author's preoccupation was oriented towards finding certain ways of keeping these dimensions before the loss of dental units. Thus, Swenson proposes the confectioning of an acryllic mask, as such maintaining the facial dimentions of the patients. Silverman recommends tatooing on the fixed mucosa in the frontal area both in the maxillary, and the mandibula, of two points. The measurement of the distance between them in the position of R.C. and I.M. will be registered and kept in each patient's chart. Material and method Material (pacients) In the study, 19 patients have been included, aged between 60-69 years, who presented full bimaxillary edentation, the edentation being between 0 and 2 years old. I have included in the study: compliant patients pacients who following the clinical exam of the cefalic extremity at an inspection from the lateral norm presented a right profile patients for whom I did not have a registered DVO kept on file prior to the edentulous state (preextraction documents) patients with kept facial symmetry I have excluded from the study: uncompliant patients patients who have previously worn dental prosthesis patients who following the clinical exam of the cefalic extremity upon inspection from the lateral norm presented a convex or concave profile patients with malformations of the facial massive Working method 1. The clinical determination of the vertical dimension of occlusion The patients were seated on the dental chair with their trunks in a vertical position and with the head resting against the headrest. At the same time, we provided a quiet atmosphere in the cabinet, seeking to remove any state of tension the patients might experience. The vertical dimension of occlusion was determined starting from the vertical rest position. 2. The performing of the lateral cefalometrics followed, on an electronic format, and their analysis, following the cefalometric analysis protocol. The computerised axiograph Cadix, through the associated softwear, has the possibility of performing the cefalometric analysis, by activating the Cadias system. Results The analysis of the lateral cefalometrics for the patients studied has shown that in only seven cases DVO clinically determined was correct. In 9 cases DVO was overdimensioned, and in 3 cases it was noted that DVO was underdimensioned. The lateral cefaometrics executed on male sex persons shows a correct determination of the DVO in 5 cases. The clinical superevaaluation was produced in 4 cases, and the subdimentioning appears in 3 cases. In the female sex, on the other hand, the clinical DVO was correctly established in 2 cases, and in 5 cases DVO was clinically overdimentioned.
Study 4. Improving the quality of life in the totally edentulous patient after prosthesis Introduction In 1998, OMS defines the quality of life thus: "the quality of life is given by the individuals' perception of their social situations in the context of the system of cultural values they live in, and in dependence with their own needs, standards, and aspirations". A more complex definition is given by I. Mrginean in 2002. He defines the quality of life through "the ensemble of elements which refer to the physical, economic, social, cultural, political, health situation etc. in which people live, the content and nature of the activities they perform, the characteristics of the relations and social processes in they participate, the goods and services they have access to, the consumption models adopted, the way of life and lifestyle, the evaluation of circumstances and the results of the activities which correspond the the expectations of the population, as well as the subjective states of satisfaction and insatisfaction, happiness, frustration,etc. Still, the statements of those investigated highlight the great importance awarded to health in their considerations, even though this appreciation is subjective most of the times. Material and method 120 patients diagnosed with bimaxillary full edentation have been included in the study. I have included in the study only compliant patients and who, upon the clinical examination, presented bimaxillary full edentation without prosthesis. I have excluded from the study uncompliant patients as well as patients who have previously worn dental prosthesis. The totally bimaxillary edentulous patients have filled out 2 identical questionnaires made up of 23 items. Both questionnaires aim to glean the patients' perception regarding chewing disorders, as well as sounding, physiognomical, and psychological disorders induced by edentulous state, the way in which these aspects: influence the oro-dental state of health influence the quality of life contribute to the modification in a negative sense of the self image and self image influence the social life, professional life determines the apparition of avoiding behavior (patients do not speak in public, only eat in the family, etc) can be corrected through specialized treatment, by wearing prosthetic pieces. The first questionnaire was filled by the patients prior to the making of dental prosthesis and contains the personal information of every person answering, as well as the interval (in months) bewteen the loss of the last denatl units, and the second questionnaire was offered for completion 6 months after the making, the application of the prosthesis and the finalising of the touch-up stages performed at the level of the prosthetic pieces. Results The absence of dental units determines in most cases the impossibility to section foods and a deficient chewing of the latter. Thus, the majority of patients questionned encounter real difficulties in the chewing act (83- very many, 37-many). After the application of the prosthesis, the raport changes substantially: 74 persons out of a total of 120 questionned signal few difficulties in the chewing act or even insignificant ones --9 cases. There are, however, patients, who signal difficulties in the chewing act even after the application of dental prosthesis and the performance of the necessary touch-ups (33 - many and just 4 persons - very many). The oro-dental situation of the patient who have enetered the study prior to the application of the prosthesis demanded the preponderent consumption of liquid foods, as well as that of soft-pasty ones. Subsequently, six months after the application of the prosthetic pieces, the consistency of the foods ingested has changed gradually, the patients questionned noting that they ingest, alongside soft pasty foods, solid foodds as well (33 cases). As a consequence of the difficulties the patients encounter in the chewing act, the patients questionned were obliged to swallow the foods without sufficiently chewing them (very often --33 cases, 87 cases, often, respectively). Once the dental prosthesis used, 5 patients questionned answer that in rare cases are they obliged to swallow the food unchewed, and 114 manage to regain the pleasure of chewing. One person did not answer this question after the application of the denatl prosthesis. After the extraction of the last dental units, gradually, the physiognomy of the face has changed for the worse, at the level of the chheks and lips very much --29 cases, much --91 cases. After the application of the denatl prosthesis, the psysiognomic aspect o the face has improved as perceived a lot --84 cases, a significant lot --36 cases. Gradually, after the loss of the dental units, 66 patients questionned note that the psysiognomy of the face is affected to a great extent, while 54 of the patients consider that the face has aged to a great extent. Wearing dental prosthesis confers a youthful aspect to patients to a very large extent -80 cases, to a large extent -36 cases. To the same question, two patients perceive facial rejuvenation to a little extent, while teo other patients do not perceive semnificant changes regarding the rejuvenated aspect of the facial extremity. The speaking and pronounciation disorders, alongside the loss of teeth, are perceived as many - 95 cases, and very many, respectively - 25 cases. The difficulties in speaking and pronounciation have improved a lot - 76 cases and and greatly- 44 cases 6 months after the application of dental prosthesis. The loss of dental units has contributed to the modification in the negative sense of the image and self- esteem in 22 cases --to a very large extent, a large extent -91 cases, and little in 7 cases. By wearing dental prosthesis, the patients have regained confidence in their own person, making the mention that the prosthetic pieces have modified their image in a positive sense (26 cases --to a very great extent, to a great extent - 90 cases and to a little extent in 4 cases). As far as the social life and insertion in the group of friends is concerned, these are affected with the loss of dental units to a very great extent -36 cases, to a great extent --84 cases. Wearing dental prosthesis makes the patient wearing these prosthetic pieces an active participant in social life, improving it (to a very great extent -39 cases, to a great extent --81 cases). Couple life, prior to prosthesis, was affected: to a very large extent --31 cases, to a large extent --30 cases, to a little extent --44 cases, and insignificantly --15 cases. Subsequently, as a consequence of wearing denatl prosthesis, this aspect was improved to a very large extent -32 cases, to a large extent -49 cases, to a little extent -- 21 cases, insignificantly -18 cases. The oro-denatl state of health, after the loss of dental units, is perceived as being precarious --104 cases, respectively satisfactory --16 cases. After the prosthesis, the oro-dental state of health is rated as very good --5 cases, good -107 cases, and satisfactory --8 cases. The subjects questionned appreciate the overall quality of life after the loss of dental units as being precarious -106 cases and in 14 cases as being satisfactory. The quality of life after the application of the prosthetic pieces is perceived as being very good 2 cases, good-110 cases and satisfactory - 8 cases. The patients questionned previous to the application of the prosthesis consider that the stomatological treatment will contribute to the improvement of the quality of life to a very large extent - 38 cases, respectively to a large extent - 82 cases. The results of our work was appreciated by the patients who have affirmed that the prosthetic pieces have contributed to the improvement of the quality of life: to a very great extent -74 cases, to a great extent, respectively -46 cases.
GENERAL CONCLUSIONS
1. Knowledege of and thorough examination of the morfo-structual elements of the totally edentulous prosthetic field help the patient in establishing exactly the support area and the succion area. 2. The analysis of the mucous-bone support offers a good perspective of the prognosis for each particular case. 3. Through the results obtained, the analysis of the mucous-bone support constitutes a useful didactic material in order to emphasize the great variability of the prosthetic fields examined. 4. Comparing the scans of the two custom trays, classical and 3D, respectively, shows the imperative necessity of creating ideal custom trays. 5. The creation of the ideal 3D custom trays offers the premises of a final printing of great accuracy. 6. The interincisive papilla can be considered an uncertain indicator of the maxillary reabsorption in the case of totally edentulous patients. 7. The width of the pallatine arch (WPA) ma be considered a marker of the bone maxillary absorption, in the entire lot studied, this indicator decreases as a medium value along with the increase of the age of the total edentation. 8. The depth of the pallatine arch (DPA) is an indicator of the he bone maxillary absorption, the values of this indicator decreasing along with the increase of the edentation's age. 9. The length of the pallatine arch (LPA) may be considered, as well, an an indicator of the maxillary absorption. 10. The accuracy in the verification of the clinical determination of DVO realized through the cefalometric analysis recommends this imagistic investigation as a good means of examining the intermaxillary relations in the case of totally edentulous patients without prosthesis. 11. The cefalometric analysis eliminates human errors and the subjective criteria of the doctor in the correct establishment of the DVO. 12. The cefalometric analysis is an objective method in determining DVO. 13. The cefalometric analysis must be used in the clinical phase of determining the intermaxillary relations in the totally edentulous patient without prosthesis. 14. Crucial in the success of the treatment are the patient's personality, level of culture and intelligence, the psychological state regarding the acceptance and adaptation to dental prosthesis. 15. A totally edentulous patient with classical prosthesis will never be able to have the chewing capacity of a dentulous patient. 16. Classical dental prosthesis, if correctly made, respond to a great extent to physiognomical demands. 17. By means of the treatment with dental prosthesis, the patient regains their self-esteem, being able to become reintegrated in social life. ORIGINALITY AND INNOVATIVE CONTRIBUTIONS OF THE THESIS
The current research contains a series of elements which confer upon it an original and innovative character, by means of the contribution brought to the clinical stages of the realization of the prosthetic pieces. The studies within the Ph.D. thesis contribute to the perfecting of the most important clinical phases in the therapeutic algorhythm, bearing a positive influence on the integration of dental prosthesis in the functioning of the dento-maxillary apparatus. The comparison of the scans of the two custom trays, the classical one, and the analysis of the 3D files, highlight real defficiencies in the making of custom trays according to the classical technique in the denatl technique laboratory. Following the research undertaken, I propose the making of ideal custom trays with the help of the 3D CATIA V5 software in order to create the premises of perfect functional printing. The method proposed falls perfectly within the use of modern and innovative means of treatment which have known an important development in the past years. Also, the research has demonstrated that the cefalometric analysis is an objective imagistic method in the establishment with accuracy of the clinical determination of the vertical dimention of the occlusion. This is precisely why I consider that th determination of DVO with the help of the cefalometric analysis should be a mandatory stage in the treatment of the totally edentulous patient through classical prosthesis. The good precision in determining the DVO with the help of lateral cefalometrics thus an objective instrument in the thereapy of total edentation. Therefore, the research carried out under the scope of this doctoral research open new perspectives towards the improvment of the clinical stages in the elaboration of prosthetic pieces, with current and large scale applicability, so that the classical dental prosthesis can assure an exceptional sanogenic status.