AgHBe

AgHBs AgHBc Replicare

infectiozitate in hepatocit Virus slbatic

AC HBs ACHBe
Vindecare Incetarea
AC HBc IgM
Imunizare replicarii
Infectie acut
AC HBc IgG
Interpretare in context
 Fereastra serologic in infectia HBV

AgHBs ACHBs
 AgHBs pozitiv

IgM HBc

pozitiv negativ

Hepatit Caut IgG

acut VHB

pozitiv negativ

Hepatit cronic EROARE

HBV
 AgHBs negativ

IgM HBc

pozitiv negativ

Caut IgG HBc

Hepatit
acut VHB pozitiv negativ
Fereastr serologic HBs
Mutant HBs Caut AC HBs Caut alt
virus
pozitiv negativ

Imunizare anti HBV Infectie ocult HBV

 IgM HBc pozitiv

AgHBe

pozitiv negativ
Replicare viral intens
Virus slbatic Caut HBV DNA

HBV DNA pozitiv HBV DNA negativ

Replicare viral intens Incetarea replicrii virale

Virus mutant
AC anti HBe
pozitiv negativ
Seroconversie HBe Fereastr serologic HBe
 Hepatita acut cu VHB cu debarasare de virus

Simptomatic

AgHBe anti-HBe

Total anti-HBc

AgHBs IgM anti-HBc anti-HBs

0 4 8 12 16 20 24 28 32 36 52 100
Sptmni dup contact infectant
 Hepatita acut cu VHB evoluia ctre cronicizarea infeciei

Acut Cronic
(6 luni) (ani)
AgHBe anti-HBe
HBsAg
Total anti-HBc

IgM anti-HBc

0 4 8 12 16 20 24 28 32 36 52 ani
Sptmni dup contact infectant
Coinfecia VHB - VHD

Simptomatologie

ALT

anti-HBs
IgM anti-HDV

ARN-VHD

AgHBs
anti-VHD totali

Timp de la contact infectant

 Suprainfecie VHD

Icter

Simptomatologie

anti-VHD total
ALT

ARN-VHD
AgHBs

IgM anti-VHD

Timp de la contact infectant

Infecia cu VHC care se limiteaz
anti-
HCV
+/-Simptomatologie

ARN-VHC

ALT

Normal

0 1 2 3 4 5 6 1 2 3 4
Luni Ani
Timp de la contactul infectant
Infecia cu VHC care cronicizeaz

anti-HCV
+/-Simptomatologie

ARN-VHC

ALT

Normal
0 1 2 3 4 5 6 1 2 3 4
Luni Ani

Timp de la contactul infectant