TRATAMENTUL FICATULUI GRAS NON-ALCOOLIC LA

ADULT

Autor: student (a) Brinza Elena

Grupa: M1826

Coordonator: prof. disciplina

gastroenterologie Alina Jucov
 Ficatul gras non-alcoolic

Ficatul gras non-alcoolic, include entități clinico-morfologice și

evolutiv diferite, care au la bază steatoza hepatică
macroveziculară și absența consumului de alcool.
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Photo courtesy of Joseph
Pulcini, M.D.
 Terapia FGNA
Tera
pia
Ciroza hepatică/ Cancer hepatic
com
plic
ațiil
or
Medicamente Steatohepatita non-alcoolică
hepatice

Steatoza hepatică non-alcoolică

Modificare regimului de viață
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 The prevalence of nonalcoholic fatty liver disease (NAFLD) is likely to increase
over time due to the epidemics of obesity and diabetes. Presently, there is no
definitive treatment for NAFLD. Based on available evidence, vitamin E (RRR-α-
tocopherol) is only recommended in NASH adults without diabetes or cirrhosis
and with aggressive histology. 

 The effects of vitamin E have been evaluated in several experimental

nutritional models of NAFLD. In mice fed with methionine-choline-deficient
(MCD) diet, vitamin E attenuated steatohepatitis, as evidenced by decreased
liver enzymes and diminished histological steatosis and necroinflammation .
This was associated with reduction in MDA, enhanced superoxide dismutase
activity, and downregulation of genes related to inflammation, apoptosis, and
fibrosis.

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Pierderile energetice a unui om de 60 kg in diferite
activitati (kcal/ora)
Somn 50
Culcat, nedormind 65

Citire in glas 90
Lucrul casnic 120-240
Mers rapid 300
Fuga 360
Innot 180-400 3 ori/sapt cite 30
Patinaj 180-600 min de alergare =
4 saptamini de
Cu bicicleta 210-540
sala
Schierea 420
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 Alimentele recomandate in ficatul gras –
alimentele lipotrope
Proteinele bogate in Brinza de vaci, carnea/pestele negras, crupele
metionina/colina de ovas, hrisca, faina de soie

Grasimele vegetale cu continut de Ulei de flaorea soarelui, de porumb, de masline,

acizi grasi nesaturati si lecitina de soie

Vitaminele grupului B, C, P Favorizeaza acumularea glicogenului in ficat,

normalizeaza metabolismul colesterolului.

 Bă uturi fă ră fructoză
 Consum moderat de cafea
NASH
 Efort moderat timp de 30 min/ 3-5 ori/să ptă mina
 Somn 7-9 ore/noapte
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 Bibliografie

• Harrison 2022
• https://msmps.gov.md/wp-content/upload
s/2020/07/14773-PCN20Ficatul20gras20n
on-alcoolic20final.pdf
• https://www.worldgastroenterology.org/N
AFLD-NASH.html
• https://www.ncbi.nlm.nih.gov/pmc/
articles/PMC4984672/

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